CD200 molecule (Q21104677)

http://www.ebi.ac.uk/interpro/protein/P41217

Immunoglobulin-like domain superfamily

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P41217

OX-2 membrane glycoprotein

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P41217

Immunoglobulin subtype, protein family

1 reference

Immunoglobulin V-set domain, protein family

1 reference

immunoglobulin-like domain, protein family

1 reference

Immunoglobulin domain, protein family

1 reference

signaling receptor binding

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41217&geneProductId=UniProtKB:P41217

1 reference

9 May 2019

A secreted protein microarray platform for extracellular protein interaction discovery

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41217

protein homodimerization activity

IPI

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41217&geneProductId=UniProtKB:P41217

cell adhesion molecule binding

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41217&geneProductId=UniProtKB:P41217

protein binding involved in heterotypic cell-cell adhesion

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41217

glycosylated region protein binding

1 reference

9 May 2019

Lymphoid/neuronal cell surface OX2 glycoprotein recognizes a novel receptor on macrophages implicated in the control of their function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41217

integral component of membrane

TAS

cell component

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41217

integral component of plasma membrane

IEA

1 reference

9 May 2019

Characterization of the human homolog of the rat MRC OX-2 membrane glycoprotein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41217

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41217&geneProductId=UniProtKB:P41217

3 references

9 May 2019

The leukocyte/neuron cell surface antigen OX2 binds to a ligand on macrophages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41217

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41217

9 May 2019

The unusual distribution of the neuronal/lymphoid cell surface CD200 (OX2) glycoprotein is conserved in humans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41217

1 reference

9 May 2019

Distribution of the Immune Inhibitory Molecules CD200 and CD200R in the Normal Central Nervous System and Multiple Sclerosis Lesions Suggests Neuron-Glia and Glia-Glia Interactions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41217

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41217

1 reference

9 May 2019

Distribution of the Immune Inhibitory Molecules CD200 and CD200R in the Normal Central Nervous System and Multiple Sclerosis Lesions Suggests Neuron-Glia and Glia-Glia Interactions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41217

heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

biological process

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41217&geneProductId=UniProtKB:P41217

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41217&geneProductId=UniProtKB:P41217

homophilic cell adhesion via plasma membrane adhesion molecules

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41217&geneProductId=UniProtKB:P41217

negative regulation of macrophage activation

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41217&geneProductId=UniProtKB:P41217

negative regulation of leukocyte activation

IEA

1 reference

9 May 2019

CD200 and membrane protein interactions in the control of myeloid cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41217

negative regulation of cell population proliferation

TAS

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41217

negative regulation of NF-kappaB transcription factor activity

1 reference

9 May 2019

CD200 increases alternatively activated macrophages through cAMP-response element binding protein - C/EBP-beta signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41217

positive regulation of CREB transcription factor activity

1 reference

9 May 2019

CD200 increases alternatively activated macrophages through cAMP-response element binding protein - C/EBP-beta signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41217

positive regulation of transforming growth factor beta production

1 reference

9 May 2019

CD200 increases alternatively activated macrophages through cAMP-response element binding protein - C/EBP-beta signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41217

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41217

positive regulation of arginase activity

1 reference

9 May 2019

CD200 increases alternatively activated macrophages through cAMP-response element binding protein - C/EBP-beta signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41217

positive regulation of protein-glutamine gamma-glutamyltransferase activity

IGI

1 reference

9 May 2019

CD200 increases alternatively activated macrophages through cAMP-response element binding protein - C/EBP-beta signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41217

regulation of neuroinflammatory response

IGI

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41217

negative regulation of neuroinflammatory response

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41217

negative regulation of neuron death

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41217

negative regulation of matrix metallopeptidase secretion

1 reference

9 May 2019

Gingival Tissue Inflammation Promotes Increased Matrix Metalloproteinase-12 Production by CD200Rlow Monocyte-Derived Cells in Periodontitis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41217

negative regulation of macrophage migration

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41217

negative regulation of T cell migration

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41217