Protein tyrosine phosphatase non-receptor type 3 (Q21105040)

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mammalian protein found in Homo sapiens

protein-tyrosine phosphatase H1
PTP-H1
tyrosine-protein phosphatase non-receptor type 3
PTPN3
cytoskeletal-associated protein tyrosine phosphatase

Language	Label	Description	Also known as
English	Protein tyrosine phosphatase non-receptor type 3	mammalian protein found in Homo sapiens	protein-tyrosine phosphatase H1 PTP-H1 tyrosine-protein phosphatase non-receptor type 3 PTPN3 cytoskeletal-associated protein tyrosine phosphatase

Statements

1 reference

13 November 2019

UniProt protein ID

Ubiquitin-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P26045

Protein-tyrosine phosphatase-like

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P26045

FERM superfamily, second domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P26045

FERM/acyl-CoA-binding protein superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P26045

PDZ superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P26045

Protein-tyrosine phosphatase, non-receptor type-3, -4

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P26045

PH-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P26045

Tyrosine specific protein phosphatases domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Band 4.1 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

FERM central domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

FERM, C-terminal PH-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

PTP type protein phosphatase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

FERM, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

PDZ domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein-tyrosine phosphatase, catalytic domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

FERM domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

FERM conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein-tyrosine phosphatase, active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

sodium channel regulator activity

determination method or standard

1 reference

8 April 2019

Cardiac sodium channel Na(v)1.5 interacts with and is regulated by the protein tyrosine phosphatase PTPH1

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26045

determination method or standard

phosphoprotein phosphatase activity

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26045

determination method or standard

phosphatase activity

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26045

determination method or standard

phosphotyrosine residue binding

determination method or standard

1 reference

8 April 2019

Identification of the cell cycle regulator VCP (p97/CDC48) as a substrate of the band 4.1-related protein-tyrosine phosphatase PTPH1

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26045

determination method or standard

determination method or standard

1 reference

8 April 2019

Identification of the cell cycle regulator VCP (p97/CDC48) as a substrate of the band 4.1-related protein-tyrosine phosphatase PTPH1

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26045

determination method or standard

cytoskeletal protein binding

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26045

determination method or standard

protein binding

determination method or standard

12 references

8 April 2019

Identification of protein tyrosine phosphatases with specificity for the ligand-activated growth hormone receptor

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26045

determination method or standard

8 April 2019

Cardiac sodium channel Na(v)1.5 interacts with and is regulated by the protein tyrosine phosphatase PTPH1

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26045

determination method or standard

8 April 2019

PTPH1 cooperates with vitamin D receptor to stimulate breast cancer growth through their mutual stabilization

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26045

determination method or standard

8 April 2019

Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26045

determination method or standard

8 April 2019

Identification of the cell cycle regulator VCP (p97/CDC48) as a substrate of the band 4.1-related protein-tyrosine phosphatase PTPH1

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26045

determination method or standard

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26045

determination method or standard

8 April 2019

Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26045

determination method or standard

8 April 2019

A human MAP kinase interactome

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26045

determination method or standard

8 April 2019

Serine phosphorylation-dependent association of the band 4.1-related protein-tyrosine phosphatase PTPH1 with 14-3-3beta protein

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26045

determination method or standard

8 April 2019

Substrate specificity and plasticity of FERM-containing protein tyrosine phosphatases

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26045

determination method or standard

8 April 2019

Protein tyrosine phosphatase H1 is a target of the E6 oncoprotein of high-risk genital human papillomaviruses

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26045

determination method or standard

8 April 2019

Evidence for regulation of the tumor necrosis factor alpha-convertase (TACE) by protein-tyrosine phosphatase PTPH1

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26045

determination method or standard

protein tyrosine phosphatase activity

determination method or standard

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26045

determination method or standard

8 April 2019

Isolation of a cDNA clone encoding a human protein-tyrosine phosphatase with homology to the cytoskeletal-associated proteins band 4.1, ezrin, and talin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26045

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26045

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26045

determination method or standard

8 April 2019

Large-scale structural analysis of the classical human protein tyrosine phosphatome

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26045

determination method or standard

hydrolase activity

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26045

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26045

determination method or standard

cytoplasmic side of plasma membrane

determination method or standard

1 reference

8 April 2019

Subcellular localization of intracellular protein tyrosine phosphatases in T cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26045

determination method or standard

biological process

regulation of membrane depolarization during action potential

determination method or standard

1 reference

8 April 2019

Cardiac sodium channel Na(v)1.5 interacts with and is regulated by the protein tyrosine phosphatase PTPH1

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26045

determination method or standard

protein dephosphorylation

determination method or standard

3 references

8 April 2019

Isolation of a cDNA clone encoding a human protein-tyrosine phosphatase with homology to the cytoskeletal-associated proteins band 4.1, ezrin, and talin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26045

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26045

determination method or standard

8 April 2019

Identification of the cell cycle regulator VCP (p97/CDC48) as a substrate of the band 4.1-related protein-tyrosine phosphatase PTPH1

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26045

determination method or standard

liver regeneration

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26045

determination method or standard

regulation of sodium ion transmembrane transporter activity

determination method or standard

1 reference

8 April 2019

Cardiac sodium channel Na(v)1.5 interacts with and is regulated by the protein tyrosine phosphatase PTPH1

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26045

determination method or standard

negative regulation of membrane protein ectodomain proteolysis

determination method or standard

1 reference

8 April 2019

Evidence for regulation of the tumor necrosis factor alpha-convertase (TACE) by protein-tyrosine phosphatase PTPH1

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26045

determination method or standard

negative regulation of mitotic cell cycle

determination method or standard

1 reference

8 April 2019

Identification of the cell cycle regulator VCP (p97/CDC48) as a substrate of the band 4.1-related protein-tyrosine phosphatase PTPH1

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26045

determination method or standard

dephosphorylation

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26045

determination method or standard

peptidyl-tyrosine dephosphorylation

determination method or standard

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26045

determination method or standard

negative regulation of epidermal growth factor receptor signaling pathway

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26045

determination method or standard

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P26045

FERM conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P26045

Tyrosine specific protein phosphatases domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P26045

FERM, N-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P26045

FERM, C-terminal PH-like domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P26045

Band 4.1 domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P26045

FERM central domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P26045

Protein-tyrosine phosphatase, active site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P26045

PTP type protein phosphatase domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P26045

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P26045

Protein-tyrosine phosphatase, catalytic

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P26045

Identifiers

MeSH descriptor ID

subject named as

Protein Tyrosine Phosphatase, Non-Receptor Type 3T

0 references

D08.811.277.352.650.775.300.300

0 references

D12.776.476.564.300.300

0 references

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000363667

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000363667

ENSP00000395384

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000395384

ENSP00000416654

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000416654

ENSP00000262539

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000262539

PDB structure ID

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

25 May 2023

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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