6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (Q21106016)

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mammalian protein found in Homo sapiens
  • PFKFB, cardiac
  • 6PF-2-K/Fru-2,6-P2ASE heart-type isozyme
  • fructose-2,6-bisphosphatase, cardiac isozyme
  • PFK/FBPase 2
  • 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2
  • 6PF-2-K/Fru-2,6-P2ase 2
  • PFKFB2
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Language Label Description Also known as
English
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
mammalian protein found in Homo sapiens
  • PFKFB, cardiac
  • 6PF-2-K/Fru-2,6-P2ASE heart-type isozyme
  • fructose-2,6-bisphosphatase, cardiac isozyme
  • PFK/FBPase 2
  • 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2
  • 6PF-2-K/Fru-2,6-P2ase 2
  • PFKFB2

Statements

molecular function
6-phosphofructo-2-kinase activity
determination method
IEA
EXP
IDA
TAS
8 references
retrieved
24 April 2018
stated in
Sequence and structure of the human 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase heart isoform gene (PFKFB2)
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O60825&geneProductId=UniProtKB:O60825
determination method
TAS
retrieved
24 April 2018
stated in
GOA
curator
UniProt
UniProt protein ID
O60825
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O60825&geneProductId=UniProtKB:O60825
determination method
IEA
retrieved
24 April 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O60825&geneProductId=UniProtKB:O60825
determination method
IEA
retrieved
24 April 2018
stated in
Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia
GOA
curator
UniProt
UniProt protein ID
O60825
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O60825&geneProductId=UniProtKB:O60825
determination method
IDA
retrieved
24 April 2018
stated in
Molecular cloning, sequence analysis, and expression of a human liver cDNA coding for fructose-6-P,2-kinase:fructose-2,6-bisphosphatase
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O60825&geneProductId=UniProtKB:O60825
determination method
EXP
retrieved
24 April 2018
stated in
Cloning, expression and chromosomal localization of a human testis 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O60825&geneProductId=UniProtKB:O60825
determination method
EXP
retrieved
24 April 2018
stated in
The kinase activity of human brain 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase is regulated via inhibition by phosphoenolpyruvate
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O60825&geneProductId=UniProtKB:O60825
determination method
EXP
retrieved
24 April 2018
stated in
Expression of human placental-type 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase in various cells and cell lines
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O60825&geneProductId=UniProtKB:O60825
determination method
EXP
6-phosphofructo-2-kinase activity
determination method
EXP
IBA
IDA
IEA
TAS
9 references
retrieved
10 September 2018
stated in
Sequence and structure of the human 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase heart isoform gene (PFKFB2)
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O60825&geneProductId=UniProtKB:O60825
determination method
TAS
retrieved
10 September 2018
stated in
GOA
curator
UniProt
UniProt protein ID
O60825
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O60825&geneProductId=UniProtKB:O60825
determination method
IEA
retrieved
10 September 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O60825&geneProductId=UniProtKB:O60825
determination method
IEA
retrieved
10 September 2018
stated in
Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia
GOA
curator
UniProt
UniProt protein ID
O60825
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O60825&geneProductId=UniProtKB:O60825
determination method
IDA
retrieved
10 September 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O60825&geneProductId=UniProtKB:O60825
determination method
IBA
retrieved
10 September 2018
stated in
Expression of human placental-type 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase in various cells and cell lines
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O60825&geneProductId=UniProtKB:O60825
determination method
EXP
retrieved
10 September 2018
stated in
Molecular cloning, sequence analysis, and expression of a human liver cDNA coding for fructose-6-P,2-kinase:fructose-2,6-bisphosphatase
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O60825&geneProductId=UniProtKB:O60825
determination method
EXP
retrieved
10 September 2018
stated in
The kinase activity of human brain 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase is regulated via inhibition by phosphoenolpyruvate
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O60825&geneProductId=UniProtKB:O60825
determination method
EXP
retrieved
10 September 2018
stated in
Cloning, expression and chromosomal localization of a human testis 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O60825&geneProductId=UniProtKB:O60825
determination method
EXP
biological process

Identifiers

 
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