Transporter 1, ATP binding cassette subfamily B member (Q21106702)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q03518

P-loop containing nucleoside triphosphate hydrolase

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q03518

antigen peptide transporter, subunit TAP1

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q03518

tapasin

1 reference

Transporter Classification Database ID

3.A.1.209.1

retrieved

2 October 2019

hierarchical database ID heuristic

AAA proteins

1 reference

ABC transporter-like, protein family

1 reference

ABC transporter type 1, transmembrane domain, protein family

1 reference

ABC transporter, conserved site, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

1 January 2018

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

protein homodimerization activity

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

ABC-type peptide transporter activity

ISS

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03518&geneProductId=UniProtKB:Q03518

4 references

1 January 2018

Identification of sequences in the human peptide transporter subunit TAP1 required for transporter associated with antigen processing (TAP) function

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03518&geneProductId=UniProtKB:Q03518

1 January 2018

Detection of TAP family dimerizations by an in vivo assay in mammalian cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03518&geneProductId=UniProtKB:Q03518

1 January 2018

Assembly and function of the two ABC transporter proteins encoded in the human major histocompatibility complex

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03518&geneProductId=UniProtKB:Q03518

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03518&geneProductId=UniProtKB:Q03518

MHC class Ib protein binding

1 reference

1 January 2018

HLA-F is a predominantly empty, intracellular, TAP-associated MHC class Ib protein with a restricted expression pattern

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

12 references

1 January 2018

Tapasin interacts with the membrane-spanning domains of both TAP subunits and enhances the structural stability of TAP1 x TAP2 Complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

1 January 2018

Structural arrangement of the transmission interface in the antigen ABC transport complex TAP.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

1 January 2018

Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

1 January 2018

Adaptor Aly and co-adaptor Thoc5 function in the Tap-p15-mediated nuclear export of HSP70 mRNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

1 January 2018

Redox regulation facilitates optimal peptide selection by MHC class I during antigen processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

1 January 2018

Specific targeting of the EBV lytic phase protein BNLF2a to the transporter associated with antigen processing results in impairment of HLA class I-restricted antigen presentation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

1 January 2018

A mechanism of viral immune evasion revealed by cryo-EM analysis of the TAP transporter

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

1 January 2018

The varicellovirus UL49.5 protein blocks the transporter associated with antigen processing (TAP) by inhibiting essential conformational transitions in the 6+6 transmembrane TAP core complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

1 January 2018

Varicelloviruses avoid T cell recognition by UL49.5-mediated inactivation of the transporter associated with antigen processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

1 January 2018

The first N-terminal transmembrane helix of each subunit of the antigenic peptide transporter TAP is essential for independent tapasin binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

1 January 2018

The varicellovirus UL49.5 protein blocks the transporter associated with antigen processing (TAP) by inhibiting essential conformational transitions in the 6+6 transmembrane TAP core complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

1 January 2018

Varicelloviruses avoid T cell recognition by UL49.5-mediated inactivation of the transporter associated with antigen processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

MHC class I protein binding

IPI

1 reference

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03518&geneProductId=UniProtKB:Q03518

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03518&geneProductId=UniProtKB:Q03518

5 references

1 January 2018

Varicelloviruses avoid T cell recognition by UL49.5-mediated inactivation of the transporter associated with antigen processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

1 January 2018

Identification of sequences in the human peptide transporter subunit TAP1 required for transporter associated with antigen processing (TAP) function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

1 January 2018

Assembly, intracellular localization, and nucleotide binding properties of the human peptide transporters TAP1 and TAP2 expressed by recombinant vaccinia viruses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

Identification of sequences in the human peptide transporter subunit TAP1 required for transporter associated with antigen processing (TAP) function

peptide antigen binding

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

1 reference

1 January 2018

Structure of the ABC ATPase domain of human TAP1, the transporter associated with antigen processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

ATPase-coupled transmembrane transporter activity

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03518&geneProductId=UniProtKB:Q03518

ABC-type peptide antigen transporter activity

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

peptide transmembrane transporter activity

3 references

1 January 2018

Modulation of the antigenic peptide transporter TAP by recombinant antibodies binding to the last five residues of TAP1

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03518&geneProductId=UniProtKB:Q03518

1 January 2018

Assembly, intracellular localization, and nucleotide binding properties of the human peptide transporters TAP1 and TAP2 expressed by recombinant vaccinia viruses

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03518&geneProductId=UniProtKB:Q03518

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03518&geneProductId=UniProtKB:Q03518

ABC-type peptide transporter activity

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

5 references

1 January 2018

Identification of sequences in the human peptide transporter subunit TAP1 required for transporter associated with antigen processing (TAP) function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

1 January 2018

Assembly and function of the two ABC transporter proteins encoded in the human major histocompatibility complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

1 January 2018

Detection of TAP family dimerizations by an in vivo assay in mammalian cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

peptide transmembrane transporter activity

4 references

1 January 2018

Modulation of the antigenic peptide transporter TAP by recombinant antibodies binding to the last five residues of TAP1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

1 January 2018

Assembly, intracellular localization, and nucleotide binding properties of the human peptide transporters TAP1 and TAP2 expressed by recombinant vaccinia viruses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

integral component of membrane

cell component

3 references

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03518&geneProductId=UniProtKB:Q03518

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03518&geneProductId=UniProtKB:Q03518

17 October 2017

Multiple regions of the transporter associated with antigen processing (TAP) contribute to its peptide binding site

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03518&geneProductId=UniProtKB:Q03518

endoplasmic reticulum membrane

2 references

3 references

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03518&geneProductId=UniProtKB:Q03518

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03518&geneProductId=UniProtKB:Q03518

17 October 2017

Defining the membrane proteome of NK cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03518&geneProductId=UniProtKB:Q03518

4 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

1 January 2018

Identification of sequences in the human peptide transporter subunit TAP1 required for transporter associated with antigen processing (TAP) function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

1 January 2018

Molecular architecture of the TAP-associated MHC class I peptide-loading complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

1 January 2018

Detection of TAP family dimerizations by an in vivo assay in mammalian cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

integral component of endoplasmic reticulum membrane

4 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

1 January 2018

Identification of sequences in the human peptide transporter subunit TAP1 required for transporter associated with antigen processing (TAP) function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

1 January 2018

Membrane localization of transporter associated with antigen processing (TAP)-like (ABCB9) visualized in vivo with a fluorescence protein-fusion technique

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

1 January 2018

Assembly, intracellular localization, and nucleotide binding properties of the human peptide transporters TAP1 and TAP2 expressed by recombinant vaccinia viruses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03518&geneProductId=UniProtKB:Q03518

microtubule organizing center

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

phagocytic vesicle membrane

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

endoplasmic reticulum-Golgi intermediate compartment membrane

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

integral component of membrane

4 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

1 January 2018

Multiple regions of the transporter associated with antigen processing (TAP) contribute to its peptide binding site

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

MHC class I peptide loading complex

1 reference

1 January 2018

Molecular architecture of the TAP-associated MHC class I peptide-loading complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

Ensembl genome database project

endoplasmic reticulum

3 references

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

adaptive immune response

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

immune system process

1 reference

1 January 2018

antigen processing and presentation of peptide antigen via MHC class I

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

antigen processing and presentation of endogenous peptide antigen via MHC class I

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

4 references

1 January 2018

Identification of sequences in the human peptide transporter subunit TAP1 required for transporter associated with antigen processing (TAP) function

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03518&geneProductId=UniProtKB:Q03518

1 January 2018

Modulation of the antigenic peptide transporter TAP by recombinant antibodies binding to the last five residues of TAP1

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03518&geneProductId=UniProtKB:Q03518

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03518&geneProductId=UniProtKB:Q03518

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03518&geneProductId=UniProtKB:Q03518

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

cytosol to endoplasmic reticulum transport

1 reference

1 January 2018

An epitope-selective, transporter associated with antigen presentation (TAP)-1/2-independent pathway and a more general TAP-1/2-dependent antigen-processing pathway allow recognition of the HIV-1 envelope glycoprotein by CD8+ CTL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent

IMP

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03518&geneProductId=UniProtKB:Q03518

vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

transmembrane transport

1 reference

1 January 2018

antigen processing and presentation of endogenous peptide antigen via MHC class I

1 reference

1 January 2018

Identification of sequences in the human peptide transporter subunit TAP1 required for transporter associated with antigen processing (TAP) function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

5 references

1 January 2018

Identification of sequences in the human peptide transporter subunit TAP1 required for transporter associated with antigen processing (TAP) function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

1 January 2018

Modulation of the antigenic peptide transporter TAP by recombinant antibodies binding to the last five residues of TAP1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03518

Transporter Classification Database ID

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

language of work or name

English

3.A.1.209.1

2 references

Transporter Classification database

retrieved

13 March 2020