HCLS1 associated protein X-1 (Q21107292)

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mammalian protein found in Homo sapiens

HSP1BP-1
HS1 binding protein
HAX1
HAX-1
HS1-binding protein 1
HS1-associating protein X-1
HCLS1-associated protein X-1
HCLS1 (and PKD2) associated protein

Language	Label	Description	Also known as
English	HCLS1 associated protein X-1	mammalian protein found in Homo sapiens	HSP1BP-1 HS1 binding protein HAX1 HAX-1 HS1-binding protein 1 HS1-associating protein X-1 HCLS1-associated protein X-1 HCLS1 (and PKD2) associated protein

Statements

1 reference

13 November 2019

UniProt protein ID

HS1-associating protein X-1

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O00165

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

protein N-terminus binding

determination method or standard

1 reference

8 April 2019

Evidence that HAX-1 is an interleukin-1 alpha N-terminal binding protein

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

protein binding

determination method or standard

11 references

8 April 2019

Mitochondrial functions and estrogen receptor-dependent nuclear translocation of pleiotropic human prohibitin 2

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

8 April 2019

Molecular interaction between HAX-1 and XIAP inhibits apoptosis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

8 April 2019

RAC3 is a pro-migratory co-activator of ERα

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

8 April 2019

hSav1 interacts with HAX1 and attenuates its anti-apoptotic effects in MCF-7 breast cancer cells

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

8 April 2019

Pelota interacts with HAX1, EIF3G and SRPX and the resulting protein complexes are associated with the actin cytoskeleton

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

8 April 2019

The classical swine fever virus N-terminal protease N(pro) binds to cellular HAX-1

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

8 April 2019

Grb7 binds to Hax‐1 and undergoes an intramolecular domain association that offers a model for Grb7 regulation

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

8 April 2019

Hax-1 identified as a two-pore channel (TPC)-binding protein

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

8 April 2019

Screening of binding proteins that interact with human Salvador 1 in a human fetal liver cDNA library by the yeast two-hybrid system

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

8 April 2019

Intracellular IL-1alpha-binding proteins contribute to biological functions of endogenous IL-1alpha in systemic sclerosis fibroblasts

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

interleukin-1 binding

determination method or standard

1 reference

8 April 2019

Evidence that HAX-1 is an interleukin-1 alpha N-terminal binding protein

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

nuclear membrane

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

nuclear envelope

determination method or standard

1 reference

8 April 2019

HAX-1, a novel intracellular protein, localized on mitochondria, directly associates with HS1, a substrate of Src family tyrosine kinases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

transcription regulator complex

determination method or standard

1 reference

8 April 2019

Interactions among HCLS1, HAX1 and LEF-1 proteins are essential for G-CSF-triggered granulopoiesis

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

mitochondrial intermembrane space

determination method or standard

1 reference

8 April 2019

Mitochondrial functions and estrogen receptor-dependent nuclear translocation of pleiotropic human prohibitin 2

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

mitochondrial outer membrane

determination method or standard

1 reference

8 April 2019

Mitochondrial functions and estrogen receptor-dependent nuclear translocation of pleiotropic human prohibitin 2

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

endoplasmic reticulum

determination method or standard

4 references

8 April 2019

HAX-1, a novel intracellular protein, localized on mitochondria, directly associates with HS1, a substrate of Src family tyrosine kinases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

determination method or standard

4 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

8 April 2019

HAX-1, a novel intracellular protein, localized on mitochondria, directly associates with HS1, a substrate of Src family tyrosine kinases

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

cytoplasmic vesicle

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

plasma membrane

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

biological process

regulation of apoptotic process

determination method or standard

1 reference

8 April 2019

Oxidative stress-induced signaling pathways implicated in the pathogenesis of Parkinson's disease

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

positive regulation of protein kinase B signaling

determination method or standard

1 reference

8 April 2019

Interactions among HCLS1, HAX1 and LEF-1 proteins are essential for G-CSF-triggered granulopoiesis

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

mitochondrion organization

determination method or standard

1 reference

8 April 2019

Mitochondrial functions and estrogen receptor-dependent nuclear translocation of pleiotropic human prohibitin 2

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

negative regulation of apoptotic process

determination method or standard

1 reference

16 July 2018

Mitochondrial functions and estrogen receptor-dependent nuclear translocation of pleiotropic human prohibitin 2

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00165&geneProductId=UniProtKB:O00165

determination method or standard

cellular response to cytokine stimulus

determination method or standard

1 reference

8 April 2019

Interactions among HCLS1, HAX1 and LEF-1 proteins are essential for G-CSF-triggered granulopoiesis

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

positive regulation of peptidyl-serine phosphorylation

determination method or standard

1 reference

8 April 2019

Interactions among HCLS1, HAX1 and LEF-1 proteins are essential for G-CSF-triggered granulopoiesis

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

regulation of actin filament polymerization

determination method or standard

1 reference

8 April 2019

Interactions among HCLS1, HAX1 and LEF-1 proteins are essential for G-CSF-triggered granulopoiesis

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

regulation of autophagy of mitochondrion

determination method or standard

1 reference

8 April 2019

Oxidative stress-induced signaling pathways implicated in the pathogenesis of Parkinson's disease

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

regulation of protein targeting to mitochondrion

determination method or standard

1 reference

8 April 2019

Oxidative stress-induced signaling pathways implicated in the pathogenesis of Parkinson's disease

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

positive regulation of peptidyl-tyrosine phosphorylation

determination method or standard

1 reference

8 April 2019

Interactions among HCLS1, HAX1 and LEF-1 proteins are essential for G-CSF-triggered granulopoiesis

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

positive regulation of granulocyte differentiation

determination method or standard

1 reference

8 April 2019

Interactions among HCLS1, HAX1 and LEF-1 proteins are essential for G-CSF-triggered granulopoiesis

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

positive regulation of phosphatidylinositol 3-kinase signaling

determination method or standard

1 reference

8 April 2019

Interactions among HCLS1, HAX1 and LEF-1 proteins are essential for G-CSF-triggered granulopoiesis

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

positive regulation of actin cytoskeleton reorganization

determination method or standard

1 reference

8 April 2019

Interactions among HCLS1, HAX1 and LEF-1 proteins are essential for G-CSF-triggered granulopoiesis

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

positive regulation of transcription by RNA polymerase II

determination method or standard

1 reference

8 April 2019

Interactions among HCLS1, HAX1 and LEF-1 proteins are essential for G-CSF-triggered granulopoiesis

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165

determination method or standard

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000329002

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000329002

ENSP00000403848

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000403848

ENSP00000411448

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000411448

ENSP00000435088

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000435088

ENSP00000394920

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000394920

ENSP00000433951

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000433951

0 references

Microsoft Academic ID

0 references

Sitelinks

Wikipedia(5 entries)

arwiki HAX1
dewiki HCLS1-assoziiertes Protein X-1
enwiki HAX1
ttwiki HAX1
ukwiki HAX1

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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