Inositol 1,4,5-trisphosphate receptor type 3 (Q21107806)

From Wikidata

Jump to navigation Jump to search

mammalian protein found in Homo sapiens

inositol 1,4,5-trisphosphate receptor type 3
type 3 InsP3 receptor
ITPR3
insP3R3
IP3 receptor
inositol 1,4,5-triphosphate receptor, type 3
IP3 receptor isoform 3
IP3R 3
Type 3 inositol 1,4,5-trisphosphate receptor

Language	Label	Description	Also known as
English	Inositol 1,4,5-trisphosphate receptor type 3	mammalian protein found in Homo sapiens	inositol 1,4,5-trisphosphate receptor type 3 type 3 InsP3 receptor ITPR3 insP3R3 IP3 receptor inositol 1,4,5-triphosphate receptor, type 3 IP3 receptor isoform 3 IP3R 3 Type 3 inositol 1,4,5-trisphosphate receptor

Statements

1 reference

13 November 2019

UniProt protein ID

inositol trisphosphate receptor type 3

0 references

Mir domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q14573

RyR/IP3 receptor binding core, RIH domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q14573

inositol 1,4,5-trisphosphate receptors

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q14573

Inositol 1,4,5-trisphosphate/ryanodine receptor domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Ion transport domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

MIR motif domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

RyR/IP3R Homology associated domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

RIH domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity

determination method

5 references

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14573&geneProductId=UniProtKB:Q14573

determination method

26 September 2017

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14573&geneProductId=UniProtKB:Q14573

determination method

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14573&geneProductId=UniProtKB:Q14573

determination method

26 September 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14573&geneProductId=UniProtKB:Q14573

determination method

26 September 2017

Distinct localization and function of (1,4,5)IP(3) receptor subtypes and the (1,3,4,5)IP(4) receptor GAP1(IP4BP) in highly purified human platelet membranes

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14573&geneProductId=UniProtKB:Q14573

determination method

ion channel activity

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

protein binding

determination method

6 references

8 April 2019

TMEM203 Is a Novel Regulator of Intracellular Calcium Homeostasis and Is Required for Spermatogenesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

8 April 2019

Agonist-activated Ca2+ influx occurs at stable plasma membrane and endoplasmic reticulum junctions

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

8 April 2019

Human Golgi antiapoptotic protein modulates intracellular calcium fluxes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

8 April 2019

BAP1 regulates IP3R3-mediated Ca2+ flux to mitochondria suppressing cell transformation

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

8 April 2019

Modulation of Ca(2+) entry by polypeptides of the inositol 1,4, 5-trisphosphate receptor (IP3R) that bind transient receptor potential (TRP): evidence for roles of TRP and IP3R in store depletion-activated Ca(2+) entry

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

8 April 2019

Caveolin-1 scaffold domain interacts with TRPC1 and IP3R3 to regulate Ca2+ store release-induced Ca2+ entry in endothelial cells

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

inositol 1,3,4,5 tetrakisphosphate binding

determination method

1 reference

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

inositol hexakisphosphate binding

determination method

1 reference

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

inositol 1,4,5 trisphosphate binding

determination method

1 reference

26 September 2017

Primary structure, ligand binding, and localization of the human type 3 inositol 1,4,5-trisphosphate receptor expressed in intestinal epithelium

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14573&geneProductId=UniProtKB:Q14573

determination method

calcium ion binding

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

phosphatidylinositol binding

determination method

1 reference

26 September 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14573&geneProductId=UniProtKB:Q14573

determination method

inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity

determination method

6 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

8 April 2019

Distinct localization and function of (1,4,5)IP(3) receptor subtypes and the (1,3,4,5)IP(4) receptor GAP1(IP4BP) in highly purified human platelet membranes

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

inositol 1,4,5 trisphosphate binding

determination method

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

8 April 2019

Primary structure, ligand binding, and localization of the human type 3 inositol 1,4,5-trisphosphate receptor expressed in intestinal epithelium

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

integral component of membrane

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

endoplasmic reticulum membrane

determination method

5 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14573&geneProductId=UniProtKB:Q14573

determination method

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14573&geneProductId=UniProtKB:Q14573

determination method

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14573&geneProductId=UniProtKB:Q14573

determination method

26 September 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14573&geneProductId=UniProtKB:Q14573

determination method

26 September 2017

Agonist-activated Ca2+ influx occurs at stable plasma membrane and endoplasmic reticulum junctions

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14573&geneProductId=UniProtKB:Q14573

determination method

determination method

3 references

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14573&geneProductId=UniProtKB:Q14573

determination method

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14573&geneProductId=UniProtKB:Q14573

determination method

26 September 2017

Defining the membrane proteome of NK cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14573&geneProductId=UniProtKB:Q14573

determination method

receptor complex

determination method

1 reference

8 April 2019

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

plasma membrane

determination method

1 reference

26 September 2017

Agonist-activated Ca2+ influx occurs at stable plasma membrane and endoplasmic reticulum junctions

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14573&geneProductId=UniProtKB:Q14573

determination method

apical part of cell

determination method

1 reference

8 April 2019

Primary structure, ligand binding, and localization of the human type 3 inositol 1,4,5-trisphosphate receptor expressed in intestinal epithelium

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

integral component of plasma membrane

determination method

1 reference

8 April 2019

Distinct localization and function of (1,4,5)IP(3) receptor subtypes and the (1,3,4,5)IP(4) receptor GAP1(IP4BP) in highly purified human platelet membranes

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

platelet dense tubular network membrane

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

determination method

1 reference

8 April 2019

Primary structure, ligand binding, and localization of the human type 3 inositol 1,4,5-trisphosphate receptor expressed in intestinal epithelium

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

nuclear outer membrane

determination method

1 reference

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

determination method

1 reference

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

neuronal cell body

determination method

1 reference

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

endoplasmic reticulum membrane

determination method

6 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

8 April 2019

Agonist-activated Ca2+ influx occurs at stable plasma membrane and endoplasmic reticulum junctions

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

determination method

sarcoplasmic reticulum

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

cytoplasmic vesicle membrane

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

secretory granule membrane

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

biological process

sensory perception of umami taste

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

regulation of cardiac conduction

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

regulation of insulin secretion

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

platelet activation

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

response to calcium ion

determination method

1 reference

8 April 2019

Caveolin-1 scaffold domain interacts with TRPC1 and IP3R3 to regulate Ca2+ store release-induced Ca2+ entry in endothelial cells

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

sensory perception of bitter taste

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

transmembrane transport

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

sensory perception of sweet taste

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

inositol phosphate-mediated signaling

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

long-term potentiation

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

G protein-coupled receptor signaling pathway

determination method

1 reference

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

positive regulation of cytosolic calcium ion concentration

determination method

1 reference

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

protein homooligomerization

determination method

1 reference

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

protein heterooligomerization

determination method

1 reference

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

release of sequestered calcium ion into cytosol

determination method

1 reference

26 September 2017

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14573&geneProductId=UniProtKB:Q14573

determination method

determination method

1 reference

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14573&geneProductId=UniProtKB:Q14573

determination method

release of sequestered calcium ion into cytosol

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14573

determination method

Ion transport domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q14573

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q14573

RyR/IP3R Homology associated domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q14573

Inositol 1,4,5-trisphosphate/ryanodine receptor domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q14573

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q14573

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000363435

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000363435

ENSP00000475177

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000475177

PDB structure ID

1 reference

9 November 2015

http://www.uniprot.org/uniprot/P70227.txt?version=135

Transporter Classification Database ID

1 reference

based on heuristic

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q21107806&oldid=2022931398"