Inositol 1,4,5-trisphosphate receptor type 1 (Q21107812)

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mammalian protein found in Homo sapiens
  • ITPR1
  • IP3 receptor isoform 1
  • IP3 receptor
  • InsP3R1
  • IP3R 1
  • type 1 inositol 1,4,5-trisphosphate receptor
  • inositol 1,4,5-triphosphate receptor, type 1
  • protein phosphatase 1, regulatory subunit 94
  • type 1 InsP3 receptor
  • inositol 1,4,5-trisphosphate receptor type 1
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Language Label Description Also known as
English
Inositol 1,4,5-trisphosphate receptor type 1
mammalian protein found in Homo sapiens
  • ITPR1
  • IP3 receptor isoform 1
  • IP3 receptor
  • InsP3R1
  • IP3R 1
  • type 1 inositol 1,4,5-trisphosphate receptor
  • inositol 1,4,5-triphosphate receptor, type 1
  • protein phosphatase 1, regulatory subunit 94
  • type 1 InsP3 receptor
  • inositol 1,4,5-trisphosphate receptor type 1

Statements

molecular function
protein binding
determination method
IPI
7 references
retrieved
8 April 2019
stated in
IRBIT suppresses IP3 receptor activity by competing with IP3 for the common binding site on the IP3 receptor
GOA
curator
UniProt
UniProt protein ID
Q14643
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14643
determination method
IPI
retrieved
8 April 2019
stated in
An IRBIT homologue lacks binding activity to inositol 1,4,5-trisphosphate receptor due to the unique N-terminal appendage
GOA
curator
UniProt
UniProt protein ID
Q14643
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14643
determination method
IPI
retrieved
8 April 2019
stated in
The Bcl-2 protein family member Bok binds to the coupling domain of inositol 1,4,5-trisphosphate receptors and protects them from proteolytic cleavage
GOA
curator
UniProt
UniProt protein ID
Q14643
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14643
determination method
IPI
retrieved
8 April 2019
stated in
Antagonism of Beclin 1-dependent autophagy by BCL-2 at the endoplasmic reticulum requires NAF-1
GOA
curator
UniProt
UniProt protein ID
Q14643
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14643
determination method
IPI
retrieved
8 April 2019
stated in
The homocysteine-inducible endoplasmic reticulum (ER) stress protein Herp counteracts mutant α-synuclein-induced ER stress via the homeostatic regulation of ER-resident calcium release channel proteins
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14643
determination method
IPI
retrieved
8 April 2019
stated in
Phosphorylation of inositol 1,4,5-trisphosphate receptors by protein kinase B/Akt inhibits Ca2+ release and apoptosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14643
determination method
IPI
retrieved
8 April 2019
stated in
Mitochondria-associated endoplasmic reticulum membrane (MAM) integrity is required for insulin signaling and is implicated in hepatic insulin resistance
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14643
determination method
IPI
cell component
biological process

Identifiers

RefSeq protein ID
 
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                    Retrieved from "https://www.wikidata.org/w/index.php?title=Q21107812&oldid=2022931402"