S100 calcium binding protein B (Q21108021)

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mammalian protein found in Homo sapiens

S-100 calcium-binding protein, beta chain
S-100 protein beta chain
S100B
S100 calcium-binding protein, beta (neural)
protein S100-B
S-100 protein subunit beta
S100 calcium-binding protein B

Language	Label	Description	Also known as
English	S100 calcium binding protein B	mammalian protein found in Homo sapiens	S-100 calcium-binding protein, beta chain S-100 protein beta chain S100B S100 calcium-binding protein, beta (neural) protein S100-B S-100 protein subunit beta S100 calcium-binding protein B

Statements

1 reference

13 November 2019

UniProt protein ID

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P04271

EF-hand domain pair

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P04271

auxiliary protein involved in transmembrane transport

1 reference

Transporter Classification Database ID

2 October 2019

based on heuristic

hierarchical database ID heuristic

EF-hand domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

S100/CaBP-9k-type, calcium binding, subdomain, protein family

1 reference

based on heuristic

inferred from protein domain or family

EF-Hand 1, calcium-binding site, protein family

1 reference

based on heuristic

inferred from protein domain or family

S100/Calbindin-D9k, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

calcium ion binding

determination method

4 references

8 April 2019

Astrocytosis and axonal proliferation in the hippocampus of S100b transgenic mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

8 April 2019

A novel calcium-sensitive switch revealed by the structure of human S100B in the calcium-bound form

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

protein homodimerization activity

determination method

3 references

8 April 2019

A novel calcium-sensitive switch revealed by the structure of human S100B in the calcium-bound form

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

8 April 2019

S100A6 and S100A11 are specific targets of the calcium- and zinc-binding S100B protein in vivo

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

metal ion binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

calcium-dependent protein binding

determination method

1 reference

8 April 2019

S100A6 and S100A11 are specific targets of the calcium- and zinc-binding S100B protein in vivo

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

protein binding

determination method

13 references

8 April 2019

S100A6 and S100A11 are specific targets of the calcium- and zinc-binding S100B protein in vivo

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

8 April 2019

Comparison of S100b protein with calmodulin: interactions with melittin and microtubule-associated tau proteins and inhibition of phosphorylation of tau proteins by protein kinase C

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

8 April 2019

LuTHy: a double-readout bioluminescence-based two-hybrid technology for quantitative mapping of protein-protein interactions in mammalian cells

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

8 April 2019

S100B and S100A6 differentially modulate cell survival by interacting with distinct RAGE (receptor for advanced glycation end products) immunoglobulin domains

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

8 April 2019

S100A6 and S100A11 are specific targets of the calcium- and zinc-binding S100B protein in vivo

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

8 April 2019

A human interactome in three quantitative dimensions organized by stoichiometries and abundances

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

8 April 2019

Next-generation sequencing to generate interactome datasets

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

8 April 2019

Towards a proteome-scale map of the human protein–protein interaction network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

8 April 2019

S100 proteins interact with the N-terminal domain of MDM2

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

8 April 2019

Structural and functional insights into RAGE activation by multimeric S100B

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

8 April 2019

Pooled-matrix protein interaction screens using Barcode Fusion Genetics

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

8 April 2019

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

identical protein binding

determination method

5 references

8 April 2019

S100A6 and S100A11 are specific targets of the calcium- and zinc-binding S100B protein in vivo

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

8 April 2019

Structural and functional insights into RAGE activation by multimeric S100B

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

8 April 2019

Pooled-matrix protein interaction screens using Barcode Fusion Genetics

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

8 April 2019

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

tau protein binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

signaling receptor binding

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

determination method

4 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

8 April 2019

S100A6 and S100A11 are specific targets of the calcium- and zinc-binding S100B protein in vivo

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

determination method

1 reference

8 April 2019

S100A6 and S100A11 are specific targets of the calcium- and zinc-binding S100B protein in vivo

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

extracellular region

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

neuronal cell body

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

perinuclear region of cytoplasm

determination method

determination method

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

8 April 2019

S100A6 and S100A11 are specific targets of the calcium- and zinc-binding S100B protein in vivo

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

extracellular space

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

biological process

determination method

1 reference

8 April 2019

Astrocytosis and axonal proliferation in the hippocampus of S100b transgenic mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

response to glucocorticoid

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

negative regulation of skeletal muscle cell differentiation

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

central nervous system development

determination method

1 reference

8 April 2019

Astrocytosis and axonal proliferation in the hippocampus of S100b transgenic mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

astrocyte differentiation

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

positive regulation of synaptic transmission

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

positive regulation of cell population proliferation

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

regulation of cell shape

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

positive regulation of apoptotic process

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

positive regulation of I-kappaB kinase/NF-kappaB signaling

determination method

1 reference

8 April 2019

S100 protein translocation in response to extracellular S100 is mediated by receptor for advanced glycation endproducts in human endothelial cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

regulation of neuronal synaptic plasticity

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

response to methylmercury

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

cell population proliferation

determination method

1 reference

1 January 2018

Astrocytosis and axonal proliferation in the hippocampus of S100b transgenic mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

innate immune response

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

cellular response to hypoxia

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

long-term potentiation

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

positive regulation of myelination

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04271

determination method

Identifiers

MeSH descriptor ID

0 references

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000291700

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000291700

ENSP00000380769

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000380769

ENSP00000356038

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000356038

PDB structure ID

1 reference

UniProt protein ID

21 March 2016

language of work or name

1 reference

UniProt protein ID

21 March 2016

language of work or name

1 reference

UniProt protein ID

21 March 2016

language of work or name

1 reference

UniProt protein ID

21 March 2016

language of work or name

1 reference

UniProt protein ID

21 March 2016

language of work or name

1 reference

UniProt protein ID

21 March 2016

language of work or name

1 reference

UniProt protein ID

21 March 2016

language of work or name

1 reference

UniProt protein ID

21 March 2016

language of work or name

1 reference

UniProt protein ID

21 March 2016

language of work or name

1 reference

UniProt protein ID

21 March 2016

language of work or name

1 reference

UniProt protein ID

21 March 2016

language of work or name

1 reference

UniProt protein ID

21 March 2016

language of work or name

1 reference

UniProt protein ID

21 March 2016

language of work or name

1 reference

UniProt protein ID

21 March 2016

language of work or name

Transporter Classification Database ID

2 references

Transporter Classification database

13 March 2020

Transporter Classification database

29 April 2020

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

25 May 2023

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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