Protein tyrosine phosphatase receptor type M (Q21108320)

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mammalian protein found in Homo sapiens

protein tyrosine phosphatase, receptor type, mu polypeptide
PTPRM
protein tyrosine phosphatase mu
receptor-type tyrosine-protein phosphatase mu

Language	Label	Description	Also known as
English	Protein tyrosine phosphatase receptor type M	mammalian protein found in Homo sapiens	protein tyrosine phosphatase, receptor type, mu polypeptide PTPRM protein tyrosine phosphatase mu receptor-type tyrosine-protein phosphatase mu

Statements

1 reference

13 November 2019

UniProt protein ID

Immunoglobulin-like fold

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P28827

Fibronectin type III superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P28827

Immunoglobulin-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P28827

Protein-tyrosine phosphatase-like

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P28827

Concanavalin A-like lectin/glucanase domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P28827

Fibronectin type III, protein family

1 reference

based on heuristic

inferred from protein domain or family

Tyrosine specific protein phosphatases domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Immunoglobulin subtype, protein family

1 reference

based on heuristic

inferred from protein domain or family

MAM domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

PTP type protein phosphatase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein-tyrosine phosphatase, catalytic domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

immunoglobulin-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Immunoglobulin domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein-tyrosine phosphatase, active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

phosphoprotein phosphatase activity

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

phosphatase activity

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

cadherin binding

determination method

1 reference

9 May 2019

Dynamic interaction of PTPmu with multiple cadherins in vivo

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

protein binding

determination method

3 references

9 May 2019

The receptor protein-tyrosine phosphatase PTPmu interacts with IQGAP1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

9 May 2019

The PTPmu protein-tyrosine phosphatase binds and recruits the scaffolding protein RACK1 to cell-cell contacts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

9 May 2019

Dynamic interaction of PTPmu with multiple cadherins in vivo

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

identical protein binding

determination method

1 reference

9 May 2019

Intramolecular interactions between the juxtamembrane domain and phosphatase domains of receptor protein-tyrosine phosphatase RPTPmu. Regulation of catalytic activity

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

protein tyrosine phosphatase activity

determination method

5 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

8 April 2019

Involvement of nectin in inactivation of integrin alpha(v)beta(3) after the establishment of cell-cell adhesion

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

8 April 2019

Synergistic effects of methylnaltrexone with 5-fluorouracil and bevacizumab on inhibition of vascular endothelial growth factor-induced angiogenesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

8 April 2019

Cell-cell adhesion mediated by a receptor-like protein tyrosine phosphatase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

transmembrane receptor protein tyrosine phosphatase activity

determination method

1 reference

9 May 2019

Intramolecular interactions between the juxtamembrane domain and phosphatase domains of receptor protein-tyrosine phosphatase RPTPmu. Regulation of catalytic activity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

hydrolase activity

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

protein tyrosine phosphatase activity

determination method

6 references

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

9 May 2019

Involvement of nectin in inactivation of integrin alpha(v)beta(3) after the establishment of cell-cell adhesion

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

9 May 2019

Synergistic effects of methylnaltrexone with 5-fluorouracil and bevacizumab on inhibition of vascular endothelial growth factor-induced angiogenesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

9 May 2019

Cell-cell adhesion mediated by a receptor-like protein tyrosine phosphatase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

determination method

1 reference

9 May 2019

The receptor protein-tyrosine phosphatase PTPmu interacts with IQGAP1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

integral component of membrane

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

integral component of plasma membrane

determination method

1 reference

9 May 2019

Cloning, expression and chromosomal localization of a new putative receptor-like protein tyrosine phosphatase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

perinuclear region of cytoplasm

determination method

1 reference

9 May 2019

The conserved immunoglobulin domain controls the subcellular localization of the homophilic adhesion receptor protein-tyrosine phosphatase mu

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

determination method

1 reference

9 May 2019

Impaired flow-induced dilation in mesenteric resistance arteries from receptor protein tyrosine phosphatase-mu-deficient mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

plasma membrane

determination method

1 reference

9 May 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

biological process

dephosphorylation

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

retina layer formation

determination method

1 reference

9 May 2019

The receptor protein tyrosine phosphatase mu, PTPμ, regulates histogenesis of the chick retina

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

protein dephosphorylation

determination method

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

8 April 2019

Intramolecular interactions between the juxtamembrane domain and phosphatase domains of receptor protein-tyrosine phosphatase RPTPmu. Regulation of catalytic activity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

8 April 2019

Cell-cell adhesion mediated by a receptor-like protein tyrosine phosphatase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

negative regulation of endothelial cell migration

determination method

1 reference

9 May 2019

Synergistic effects of methylnaltrexone with 5-fluorouracil and bevacizumab on inhibition of vascular endothelial growth factor-induced angiogenesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

negative regulation of endothelial cell proliferation

determination method

1 reference

9 May 2019

Synergistic effects of methylnaltrexone with 5-fluorouracil and bevacizumab on inhibition of vascular endothelial growth factor-induced angiogenesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

negative regulation of angiogenesis

determination method

1 reference

9 May 2019

Synergistic effects of methylnaltrexone with 5-fluorouracil and bevacizumab on inhibition of vascular endothelial growth factor-induced angiogenesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

signal transduction

determination method

1 reference

9 May 2019

PTPmu signaling via PKCdelta is instructive for retinal ganglion cell guidance

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

homophilic cell adhesion via plasma membrane adhesion molecules

determination method

1 reference

9 May 2019

Cell-cell adhesion mediated by a receptor-like protein tyrosine phosphatase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

retinal ganglion cell axon guidance

determination method

1 reference

9 May 2019

PTPmu signaling via PKCdelta is instructive for retinal ganglion cell guidance

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

peptidyl-tyrosine dephosphorylation

determination method

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

protein dephosphorylation

determination method

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

9 May 2019

Intramolecular interactions between the juxtamembrane domain and phosphatase domains of receptor protein-tyrosine phosphatase RPTPmu. Regulation of catalytic activity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

9 May 2019

Cell-cell adhesion mediated by a receptor-like protein tyrosine phosphatase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28827

determination method

immunoglobulin domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P28827

fibronectin type III

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P28827

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P28827

immunoglobulin-like domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P28827

Tyrosine specific protein phosphatases domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P28827

Protein-tyrosine phosphatase, active site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P28827

PTP type protein phosphatase domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P28827

immunoglobulin subtype

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P28827

Protein-tyrosine phosphatase, catalytic

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P28827

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

8 February 2020

1 reference

8 February 2020

1 reference

8 February 2020

1 reference

8 February 2020

1 reference

8 February 2020

1 reference

8 February 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000331418

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000331418

ENSP00000463325

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000463325

ENSP00000382927

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000382927

ENSP00000382933

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000382933

ENSP00000462176

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000462176

ENSP00000462809

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000462809

ENSP00000463558

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000463558

ENSP00000464128

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000464128

PDB structure ID

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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