Protein tyrosine phosphatase non-receptor type 12 (Q21109575)

http://www.ebi.ac.uk/interpro/protein/Q05209

protein-tyrosine phosphatase, non-receptor type-12

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q05209

Tyrosine specific protein phosphatases domain, protein family

1 reference

PTP type protein phosphatase domain, protein family

1 reference

Protein-tyrosine phosphatase, catalytic domain, protein family

1 reference

Protein-tyrosine phosphatase, active site, protein family

1 reference

Association of PTP-PEST with the SH3 domain of p130cas; a novel mechanism of protein tyrosine phosphatase substrate recognition

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05209

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05209

11 references

8 April 2019

Association of PTP-PEST with the SH3 domain of p130cas; a novel mechanism of protein tyrosine phosphatase substrate recognition

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05209

8 April 2019

Large-scale structural analysis of the classical human protein tyrosine phosphatome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05209

8 April 2019

Mutations in CD2BP1 disrupt binding to PTP PEST and are responsible for PAPA syndrome, an autoinflammatory disorder

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05209

8 April 2019

Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05209

8 April 2019

The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05209

8 April 2019

Identification of protein tyrosine phosphatases associating with the PDGF receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05209

8 April 2019

Activation of multiple proto-oncogenic tyrosine kinases in breast cancer via loss of the PTPN12 phosphatase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05209

8 April 2019

Charting the molecular links between driver and susceptibility genes in colorectal cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05209

8 April 2019

Association of PTP-PEST with the SH3 domain of p130cas; a novel mechanism of protein tyrosine phosphatase substrate recognition

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05209

8 April 2019

Regulation of epidermal growth factor receptor trafficking by lysine deacetylase HDAC6

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05209

8 April 2019

Charting the molecular network of the drug target Bcr-Abl

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05209

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05209

non-membrane spanning protein tyrosine phosphatase activity

IEA

1 reference

8 April 2019

Cloning and expression of PTP-PEST. A novel, human, nontransmembrane protein tyrosine phosphatase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05209

phosphoprotein phosphatase activity

protein tyrosine phosphatase activity

IEA

IDA

3 references

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05209

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05209

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05209

8 April 2019

Activation of multiple proto-oncogenic tyrosine kinases in breast cancer via loss of the PTPN12 phosphatase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05209

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05209

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05209

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05209

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05209

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05209

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05209

protein dephosphorylation

IEA

4 references

8 April 2019

Cloning and expression of PTP-PEST. A novel, human, nontransmembrane protein tyrosine phosphatase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05209

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05209

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05209

8 April 2019

Crystal Structure and Substrate Specificity of PTPN12

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05209

regulation of epidermal growth factor receptor signaling pathway

IDA

1 reference

8 April 2019

Crystal Structure and Substrate Specificity of PTPN12

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05209

peptidyl-tyrosine dephosphorylation

IMP

1 reference

8 April 2019

Crystal Structure and Substrate Specificity of PTPN12

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05209

cellular response to epidermal growth factor stimulus

IDA

1 reference

8 April 2019

Crystal Structure and Substrate Specificity of PTPN12

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05209

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05209

IMP

ERBB2 signaling pathway

1 reference

8 April 2019

negative regulation of ERBB signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05209

negative regulation of platelet-derived growth factor receptor-beta signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05209

cellular response to cytokine stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05209