COP9 signalosome subunit 5 (Q21109641)

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mammalian protein found in Homo sapiens
  • testis secretory sperm-binding protein Li 231m
  • 38 kDa Mov34 homolog
  • COP9 constitutive photomorphogenic homolog subunit 5
  • COPS5
  • signalosome subunit 5
  • COP9 signalosome complex subunit 5
  • jun activation domain-binding protein 1
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Language Label Description Also known as
English
COP9 signalosome subunit 5
mammalian protein found in Homo sapiens
  • testis secretory sperm-binding protein Li 231m
  • 38 kDa Mov34 homolog
  • COP9 constitutive photomorphogenic homolog subunit 5
  • COPS5
  • signalosome subunit 5
  • COP9 signalosome complex subunit 5
  • jun activation domain-binding protein 1

Statements

molecular function
protein binding
determination method
IPI
23 references
retrieved
8 April 2019
stated in
Interaction of the stress protein p8 with Jab1 is required for Jab1-dependent p27 nuclear-to-cytoplasm translocation
GOA
curator
UniProt
UniProt protein ID
Q92905
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92905
determination method
IPI
retrieved
8 April 2019
stated in
Myeloma overexpressed 2 (Myeov2) regulates L11 subnuclear localization through Nedd8 modification
GOA
curator
UniProt
UniProt protein ID
Q92905
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92905
determination method
IPI
retrieved
8 April 2019
stated in
RIG-G as a key mediator of the antiproliferative activity of interferon-related pathways through enhancing p21 and p27 proteins
GOA
curator
UniProt
UniProt protein ID
Q92905
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92905
determination method
IPI
retrieved
8 April 2019
stated in
CSNAP Is a Stoichiometric Subunit of the COP9 Signalosome
GOA
curator
UniProt
UniProt protein ID
Q92905
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92905
determination method
IPI
retrieved
8 April 2019
stated in
Fank1 interacts with Jab1 and regulates cell apoptosis via the AP-1 pathway
GOA
curator
UniProt
UniProt protein ID
Q92905
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92905
determination method
IPI
retrieved
8 April 2019
stated in
JAB1 participates in unfolded protein responses by association and dissociation with IRE1
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92905
determination method
IPI
retrieved
8 April 2019
stated in
COP9 signalosome subunit 6 stabilizes COP1, which functions as an E3 ubiquitin ligase for 14-3-3σ
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92905
determination method
IPI
retrieved
8 April 2019
stated in
Structural insights into the COP9 signalosome and its common architecture with the 26S proteasome lid and eIF3.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92905
determination method
IPI
retrieved
8 April 2019
stated in
Cullin-RING ubiquitin E3 ligase regulation by the COP9 signalosome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92905
determination method
IPI
retrieved
8 April 2019
stated in
Jab1/CSN5, a component of the COP9 signalosome, regulates transforming growth factor beta signaling by binding to Smad7 and promoting its degradation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92905
determination method
IPI
retrieved
8 April 2019
stated in
Crystal structure of the human COP9 signalosome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92905
determination method
IPI
retrieved
8 April 2019
stated in
Defining the human deubiquitinating enzyme interaction landscape
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92905
determination method
IPI
retrieved
8 April 2019
stated in
RIG-G as a key mediator of the antiproliferative activity of interferon-related pathways through enhancing p21 and p27 proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92905
determination method
IPI
retrieved
8 April 2019
stated in
C10ORF97 is a novel tumor-suppressor gene of non-small-cell lung cancer and a functional variant of this gene increases the risk of non-small-cell lung cancer
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92905
determination method
IPI
retrieved
8 April 2019
stated in
Dynamic regulation of the COP9 signalosome in response to DNA damage
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92905
determination method
IPI
retrieved
8 April 2019
stated in
Human homologue of maid is a useful marker protein in hepatocarcinogenesis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92905
determination method
IPI
retrieved
8 April 2019
stated in
Thioredoxin modulates activator protein 1 (AP-1) activity and p27Kip1 degradation through direct interaction with Jab1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92905
determination method
IPI
retrieved
8 April 2019
stated in
COP9 signalosome controls the Carma1-Bcl10-Malt1 complex upon T-cell stimulation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92905
determination method
IPI
retrieved
8 April 2019
stated in
MOR is not enough: identification of novel mu-opioid receptor interacting proteins using traditional and modified membrane yeast two-hybrid screens
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92905
determination method
IPI
retrieved
8 April 2019
stated in
Characterization of the human COP9 signalosome complex using affinity purification and mass spectrometry
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92905
determination method
IPI
retrieved
8 April 2019
stated in
Interaction and colocalization of PGP9.5 with JAB1 and p27(Kip1)
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92905
determination method
IPI
retrieved
8 April 2019
stated in
Jab1, a novel protease-activated receptor-2 (PAR-2)-interacting protein, is involved in PAR-2-induced activation of activator protein-1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92905
determination method
IPI
retrieved
8 April 2019
stated in
K63-specific deubiquitination by two JAMM/MPN+ complexes: BRISC-associated Brcc36 and proteasomal Poh1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92905
determination method
IPI
cell component
biological process

Identifiers

 
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