CCR4-NOT transcription complex subunit 2 (Q21109876)

1 reference

8 April 2019

CNOT2 depletion disrupts and inhibits the CCR4-NOT deadenylase complex and induces apoptotic cell death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZN8

transcription coregulator activity

TAS

protein binding

7 references

8 April 2019

Depletion of mammalian CCR4b deadenylase triggers elevation of the p27Kip1 mRNA level and impairs cell growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZN8

8 April 2019

GW182 proteins directly recruit cytoplasmic deadenylase complexes to miRNA targets

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZN8

8 April 2019

Human Ccr4-Not complex is a ligand-dependent repressor of nuclear receptor-mediated transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZN8

8 April 2019

A human interactome in three quantitative dimensions organized by stoichiometries and abundances

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZN8

8 April 2019

Towards a proteome-scale map of the human protein–protein interaction network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZN8

8 April 2019

miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4-NOT

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZN8

8 April 2019

Isolation and characterization of human orthologs of yeast CCR4-NOT complex subunits

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZN8

cell component

membrane

1 reference

17 October 2017

Defining the membrane proteome of NK cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NZN8&geneProductId=UniProtKB:Q9NZN8

CCR4-NOT complex

1 reference

8 April 2019

Human Ccr4-Not complexes contain variable deadenylase subunits

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZN8

P-body

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZN8

CCR4-NOT core complex

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NZN8&geneProductId=UniProtKB:Q9NZN8

1 reference

17 October 2017

nucleus

Isolation and characterization of human orthologs of yeast CCR4-NOT complex subunits

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZN8

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZN8

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZN8

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZN8

8 April 2019

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZN8

1 reference

8 April 2019

membrane

HDA

1 reference

8 April 2019

Defining the membrane proteome of NK cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZN8

nuclear-transcribed mRNA poly(A) tail shortening

HDA

biological process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZN8

1 reference

8 April 2019

negative regulation of translation

TAS

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZN8

regulation of transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZN8

1 reference

8 April 2019

regulation of transcription by RNA polymerase II

NAS

1 reference

8 April 2019

Isolation and characterization of human orthologs of yeast CCR4-NOT complex subunits

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZN8

negative regulation of transcription by RNA polymerase II

NAS

transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NZN8&geneProductId=UniProtKB:Q9NZN8

1 reference

17 October 2017

multicellular organism development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZN8

1 reference

8 April 2019

positive regulation of cytoplasmic mRNA processing body assembly

1 reference

8 April 2019

CNOT2 depletion disrupts and inhibits the CCR4-NOT deadenylase complex and induces apoptotic cell death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZN8

trophectodermal cell differentiation

Ensembl genome database project

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZN8

gene silencing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZN8

1 reference

8 April 2019

negative regulation of intracellular estrogen receptor signaling pathway

1 reference

8 April 2019

Human Ccr4-Not complex is a ligand-dependent repressor of nuclear receptor-mediated transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZN8

regulation of translation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZN8

1 reference

8 April 2019

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NZN8&geneProductId=UniProtKB:Q9NZN8

1 reference

17 October 2017

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZN8

1 reference

8 April 2019

RNA phosphodiester bond hydrolysis, exonucleolytic

TAS

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZN8

regulation of stem cell population maintenance

Cnot1, Cnot2, and Cnot3 maintain mouse and human ESC identity and inhibit extraembryonic differentiation

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZN8

Ensembl genome database project

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZN8

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZN8

Identifiers

1 reference

30 May 2020

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30 May 2020

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13 November 2019

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9 August 2016

1 reference

9 August 2016

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9 August 2016

1 reference

9 August 2016