Complement C1q binding protein (Q21110443)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q07021

Mitochondrial glycoprotein

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q07021

Putative uncharacterized transport proteins

1 reference

Transporter Classification Database ID

9.B.103.1.1

retrieved

2 October 2019

based on heuristic

hierarchical database ID heuristic

1 reference

13 November 2019

1 reference

13 November 2019

transcription corepressor activity

1 reference

16 July 2018

Human p32, interacts with B subunit of the CCAAT-binding factor, CBF/NF-Y, and inhibits CBF-mediated transcription activation in vitro

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07021&geneProductId=UniProtKB:Q07021

transcription factor binding

1 reference

16 July 2018

Human p32, interacts with B subunit of the CCAAT-binding factor, CBF/NF-Y, and inhibits CBF-mediated transcription activation in vitro

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07021&geneProductId=UniProtKB:Q07021

19 references

8 April 2019

CDC2L5, a Cdk-like kinase with RS domain, interacts with the ASF/SF2-associated protein p32 and affects splicing in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

8 April 2019

Novel tyrosine phosphorylated and cardiolipin-binding protein CLPABP functions as mitochondrial RNA granule

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

8 April 2019

Binding of cellular p32 protein to the rubella virus P150 replicase protein via PxxPxR motifs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

8 April 2019

Identification of the zinc-dependent endothelial cell binding protein for high molecular weight kininogen and factor XII: identity with the receptor that binds to the globular "heads" of C1q (gC1q-R)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

8 April 2019

The autophagic inducer smARF interacts with and is stabilized by the mitochondrial p32 protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

8 April 2019

Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

8 April 2019

Human p32 is a novel FOXC1-interacting protein that regulates FOXC1 transcriptional activity in ocular cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

8 April 2019

Interaction between complement receptor gC1qR and hepatitis C virus core protein inhibits T-lymphocyte proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

8 April 2019

CDC2L5, a Cdk-like kinase with RS domain, interacts with the ASF/SF2-associated protein p32 and affects splicing in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

8 April 2019

Physical and functional interaction between BH3-only protein Hrk and mitochondrial pore-forming protein p32

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

8 April 2019

The binding protein for globular heads of complement C1q, gC1qR. Functional expression and characterization as a novel vitronectin binding factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

8 April 2019

The N-terminal conserved domain of rubella virus capsid interacts with the C-terminal region of cellular p32 and overexpression of p32 enhances the viral infectivity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

8 April 2019

Protein kinase C [micro] is regulated by the multifunctional chaperon protein p32

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

8 April 2019

Analysis of the Interaction between Globular Head Modules of Human C1q and Its Candidate Receptor gC1qR.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

8 April 2019

Exploration of panviral proteome: high-throughput cloning and functional implications in virus-host interactions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

8 April 2019

NONO and RALY proteins are required for YB-1 oxaliplatin induced resistance in colon adenocarcinoma cell lines

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

8 April 2019

Inhibition of RIG-I and MDA5-dependent antiviral response by gC1qR at mitochondria

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

8 April 2019

C1QBP negatively regulates the activation of oncoprotein YBX1 in the renal cell carcinoma as revealed by interactomics analysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

8 April 2019

A host YB-1 ribonucleoprotein complex is hijacked by hepatitis C virus for the control of NS3-dependent particle production

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

Molecular cloning of human fibroblast hyaluronic acid-binding protein confirms its identity with P-32, a protein co-purified with splicing factor SF2. Hyaluronic acid-binding protein as P-32 protein, co-purified with splicing factor SF2

IPI

hyaluronic acid binding

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07021&geneProductId=UniProtKB:Q07021

1 reference

16 July 2018

Isolation and characterization of the kininogen-binding protein p33 from endothelial cells. Identity with the gC1q receptor

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07021&geneProductId=UniProtKB:Q07021

mitochondrial ribosome binding

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07021&geneProductId=UniProtKB:Q07021

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07021&geneProductId=UniProtKB:Q07021

ISS

protein kinase C binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

complement component C1q complex binding

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

8 April 2019

Isolation, cDNA cloning, and overexpression of a 33-kD cell surface glycoprotein that binds to the globular "heads" of C1q

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

transcription corepressor activity

hyaluronic acid binding

transcription factor binding

2 references

translation activator activity

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

1 reference

8 April 2019

Human p32, interacts with B subunit of the CCAAT-binding factor, CBF/NF-Y, and inhibits CBF-mediated transcription activation in vitro

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

1 reference

16 July 2018

HCV core protein interaction with gC1q receptor inhibits Th1 differentiation of CD4+ T cells via suppression of dendritic cell IL-12 production

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07021&geneProductId=UniProtKB:Q07021

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

8 April 2019

Expression and colocalization of cytokeratin 1 and urokinase plasminogen activator receptor on endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

8 April 2019

Isolation and characterization of the kininogen-binding protein p33 from endothelial cells. Identity with the gC1q receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

5 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07021&geneProductId=UniProtKB:Q07021

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07021&geneProductId=UniProtKB:Q07021

16 July 2018

Inhibition of RIG-I and MDA5-dependent antiviral response by gC1qR at mitochondria

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07021&geneProductId=UniProtKB:Q07021

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07021&geneProductId=UniProtKB:Q07021

16 July 2018

Localization of P32 protein (gC1q-R) in mitochondria and at specific extramitochondrial locations in normal tissues

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07021&geneProductId=UniProtKB:Q07021

3 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07021&geneProductId=UniProtKB:Q07021

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07021&geneProductId=UniProtKB:Q07021

16 July 2018

Human p32, interacts with B subunit of the CCAAT-binding factor, CBF/NF-Y, and inhibits CBF-mediated transcription activation in vitro

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07021&geneProductId=UniProtKB:Q07021

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

4 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07021&geneProductId=UniProtKB:Q07021

16 July 2018

Isolation, cDNA cloning, and overexpression of a 33-kD cell surface glycoprotein that binds to the globular "heads" of C1q

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07021&geneProductId=UniProtKB:Q07021

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07021&geneProductId=UniProtKB:Q07021

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07021&geneProductId=UniProtKB:Q07021

presynaptic active zone

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

glutamatergic synapse

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

8 April 2019

Human p32, interacts with B subunit of the CCAAT-binding factor, CBF/NF-Y, and inhibits CBF-mediated transcription activation in vitro

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

6 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

8 April 2019

Inhibition of RIG-I and MDA5-dependent antiviral response by gC1qR at mitochondria

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

8 April 2019

Localization of P32 protein (gC1q-R) in mitochondria and at specific extramitochondrial locations in normal tissues

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

8 April 2019

Isolation, cDNA cloning, and overexpression of a 33-kD cell surface glycoprotein that binds to the globular "heads" of C1q

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

blood coagulation, intrinsic pathway

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

positive regulation of mitochondrial translation

TAS

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07021&geneProductId=UniProtKB:Q07021

negative regulation of interferon-gamma production

ISS

1 reference

8 April 2019

HCV core protein interaction with gC1q receptor inhibits Th1 differentiation of CD4+ T cells via suppression of dendritic cell IL-12 production

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

positive regulation of protein kinase B signaling

1 reference

8 April 2019

gC1q receptor ligation selectively down-regulates human IL-12 production through activation of the phosphoinositide 3-kinase pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

negative regulation of MDA-5 signaling pathway

1 reference

8 April 2019

Inhibition of RIG-I and MDA5-dependent antiviral response by gC1qR at mitochondria

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

regulation of transcription, DNA-templated

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07021&geneProductId=UniProtKB:Q07021

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

adaptive immune response

1 reference

8 April 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

negative regulation of defense response to virus

1 reference

8 April 2019

Inhibition of RIG-I and MDA5-dependent antiviral response by gC1qR at mitochondria

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

immune system process

1 reference

8 April 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

negative regulation of transcription by RNA polymerase II

1 reference

8 April 2019

Human p32, interacts with B subunit of the CCAAT-binding factor, CBF/NF-Y, and inhibits CBF-mediated transcription activation in vitro

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

transcription, DNA-templated

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07021&geneProductId=UniProtKB:Q07021

positive regulation of trophoblast cell migration

1 reference

8 April 2019

An alternative role of C1q in cell migration and tissue remodeling: contribution to trophoblast invasion and placental development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

positive regulation of substrate adhesion-dependent cell spreading

1 reference

8 April 2019

Cooperation of C1q receptors and integrins in C1q-mediated endothelial cell adhesion and spreading

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

Splicing factor 2-associated protein p32 participates in ribosome biogenesis by regulating the binding of Nop52 and fibrillarin to preribosome particles

mature ribosome assembly

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07021&geneProductId=UniProtKB:Q07021

negative regulation of mRNA splicing, via spliceosome

1 reference

16 July 2018

The splicing factor-associated protein, p32, regulates RNA splicing by inhibiting ASF/SF2 RNA binding and phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07021&geneProductId=UniProtKB:Q07021

1 reference

8 April 2019

Isolation, cDNA cloning, and overexpression of a 33-kD cell surface glycoprotein that binds to the globular "heads" of C1q

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

positive regulation of neutrophil chemotaxis

1 reference

8 April 2019

C1q-mediated chemotaxis by human neutrophils: involvement of gClqR and G-protein signalling mechanisms

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

complement activation, classical pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

positive regulation of apoptotic process

1 reference

8 April 2019

Physical and functional interaction between BH3-only protein Hrk and mitochondrial pore-forming protein p32

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

phosphatidylinositol 3-kinase signaling

1 reference

8 April 2019

gC1q receptor ligation selectively down-regulates human IL-12 production through activation of the phosphoinositide 3-kinase pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

innate immune response

1 reference

8 April 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

positive regulation of dendritic cell chemotaxis

1 reference

8 April 2019

Chemotaxis of human monocyte-derived dendritic cells to complement component C1q is mediated by the receptors gC1qR and cC1qR

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

regulation of complement activation

1 reference

16 July 2018

Isolation, cDNA cloning, and overexpression of a 33-kD cell surface glycoprotein that binds to the globular "heads" of C1q

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07021&geneProductId=UniProtKB:Q07021

negative regulation of RIG-I signaling pathway

1 reference

8 April 2019

Inhibition of RIG-I and MDA5-dependent antiviral response by gC1qR at mitochondria

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

positive regulation of cell adhesion

1 reference

8 April 2019

An alternative role of C1q in cell migration and tissue remodeling: contribution to trophoblast invasion and placental development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

negative regulation of interleukin-12 production

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07021

regulation of complement activation

mature ribosome assembly

negative regulation of mRNA splicing, via spliceosome

Transporter Classification Database ID

Identifiers

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

30 June 2016

language of work or name

1 reference

30 June 2016

language of work or name

English

9.B.103.1.1

2 references

Transporter Classification database

retrieved

13 March 2020