INSM transcriptional repressor 1 (Q21111107)

http://www.ebi.ac.uk/interpro/protein/Q01101

Zinc finger C2H2-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

DNA-binding transcription factor activity

3 references

9 May 2019

Identification of an INSM1-binding site in the insulin promoter: negative regulation of the insulin gene transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

9 May 2019

Neuroendocrine differentiation factor, IA-1, is a transcriptional repressor and contains a specific DNA-binding domain: identification of consensus IA-1 binding sequence

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

9 May 2019

INSM1 functions as a transcriptional repressor of the neuroD/beta2 gene through the recruitment of cyclin D1 and histone deacetylases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

histone deacetylase binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

RNA polymerase II cis-regulatory region sequence-specific DNA binding

3 references

9 May 2019

Identification of an INSM1-binding site in the insulin promoter: negative regulation of the insulin gene transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

9 May 2019

Neuroendocrine differentiation factor, IA-1, is a transcriptional repressor and contains a specific DNA-binding domain: identification of consensus IA-1 binding sequence

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

9 May 2019

INSM1 functions as a transcriptional repressor of the neuroD/beta2 gene through the recruitment of cyclin D1 and histone deacetylases

GOA

curator

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

DNA-binding transcription repressor activity, RNA polymerase II-specific

2 references

5 June 2018

INSM1 functions as a transcriptional repressor of the neuroD/beta2 gene through the recruitment of cyclin D1 and histone deacetylases

GOA

curator

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01101&geneProductId=UniProtKB:Q01101

8 April 2019

INSM1 functions as a transcriptional repressor of the neuroD/beta2 gene through the recruitment of cyclin D1 and histone deacetylases

GOA

curator

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

Zinc finger transcription factor INSM1 interrupts cyclin D1 and CDK4 binding and induces cell cycle arrest

chromatin DNA binding

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

9 May 2019

Identification of an INSM1-binding site in the insulin promoter: negative regulation of the insulin gene transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

9 May 2019

INSM1 functions as a transcriptional repressor of the neuroD/beta2 gene through the recruitment of cyclin D1 and histone deacetylases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

DNA-binding transcription repressor activity, RNA polymerase II-specific

IPI

transcription repressor complex

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

transcription repressor complex

3 references

9 May 2019

Identification of an INSM1-binding site in the insulin promoter: negative regulation of the insulin gene transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

9 May 2019

INSM1 functions as a transcriptional repressor of the neuroD/beta2 gene through the recruitment of cyclin D1 and histone deacetylases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

negative regulation of protein phosphorylation

biological process

1 reference

9 May 2019

Zinc finger transcription factor INSM1 interrupts cyclin D1 and CDK4 binding and induces cell cycle arrest

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

regulation of transcription, DNA-templated

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01101&geneProductId=UniProtKB:Q01101

positive regulation of cell migration

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

negative regulation of transcription by RNA polymerase II

4 references

8 April 2019

Identification of an INSM1-binding site in the insulin promoter: negative regulation of the insulin gene transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

8 April 2019

Zinc finger transcription factor INSM1 interrupts cyclin D1 and CDK4 binding and induces cell cycle arrest

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

8 April 2019

INSM1 functions as a transcriptional repressor of the neuroD/beta2 gene through the recruitment of cyclin D1 and histone deacetylases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

8 April 2019

Neuroendocrine differentiation factor, IA-1, is a transcriptional repressor and contains a specific DNA-binding domain: identification of consensus IA-1 binding sequence

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

nervous system development

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

transcription, DNA-templated

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01101&geneProductId=UniProtKB:Q01101

multicellular organism development

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

endocrine system development

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

positive regulation of cell population proliferation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

type B pancreatic cell development

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

regulation of protein-containing complex assembly

1 reference

9 May 2019

Zinc finger transcription factor INSM1 interrupts cyclin D1 and CDK4 binding and induces cell cycle arrest

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

negative regulation of cell population proliferation

1 reference

9 May 2019

Zinc finger transcription factor INSM1 interrupts cyclin D1 and CDK4 binding and induces cell cycle arrest

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

1 reference

9 May 2019

IA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

negative regulation of transcription by RNA polymerase II

5 references

9 May 2019

Identification of an INSM1-binding site in the insulin promoter: negative regulation of the insulin gene transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

9 May 2019

Zinc finger transcription factor INSM1 interrupts cyclin D1 and CDK4 binding and induces cell cycle arrest

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

9 May 2019

Neuroendocrine differentiation factor, IA-1, is a transcriptional repressor and contains a specific DNA-binding domain: identification of consensus IA-1 binding sequence

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

9 May 2019

INSM1 functions as a transcriptional repressor of the neuroD/beta2 gene through the recruitment of cyclin D1 and histone deacetylases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

regulation of cell cycle process

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

neuron differentiation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01101

has part(s)

Zinc finger C2H2-type

1 reference

stated in

InterPro Release 71.0