Vav guanine nucleotide exchange factor 1 (Q21111121)

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mammalian protein found in Homo sapiens
  • proto-oncogene vav
  • VAV1
  • vav 1 oncogene
  • vav 1 guanine nucleotide exchange factor
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Language Label Description Also known as
English
Vav guanine nucleotide exchange factor 1
mammalian protein found in Homo sapiens
  • proto-oncogene vav
  • VAV1
  • vav 1 oncogene
  • vav 1 guanine nucleotide exchange factor

Statements

part of
molecular function
protein binding
determination method
IPI
18 references
retrieved
8 April 2019
stated in
Activation of Vav by Nef induces cytoskeletal rearrangements and downstream effector functions
GOA
curator
UniProt
UniProt protein ID
P15498
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15498
determination method
IPI
retrieved
8 April 2019
stated in
Phosphorylation of the linker for activation of T-cells by Itk promotes recruitment of Vav
GOA
curator
UniProt
UniProt protein ID
P15498
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15498
determination method
IPI
retrieved
8 April 2019
stated in
Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15498
determination method
IPI
retrieved
8 April 2019
stated in
LuTHy: a double-readout bioluminescence-based two-hybrid technology for quantitative mapping of protein-protein interactions in mammalian cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15498
determination method
IPI
retrieved
8 April 2019
stated in
Recruitment and activation of PLCgamma1 in T cells: a new insight into old domains
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15498
determination method
IPI
retrieved
8 April 2019
stated in
c-Abl kinase is required for beta 2 integrin-mediated neutrophil adhesion
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15498
determination method
IPI
retrieved
8 April 2019
stated in
Regulation of NK cell-mediated cytotoxicity by the adaptor protein 3BP2
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15498
determination method
IPI
retrieved
8 April 2019
stated in
The adaptor protein 3BP2 associates with VAV guanine nucleotide exchange factors to regulate NFAT activation by the B-cell antigen receptor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15498
determination method
IPI
retrieved
8 April 2019
stated in
The association of Sam68 with Vav1 contributes to tumorigenesis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15498
determination method
IPI
retrieved
8 April 2019
stated in
Crucial structural role for the PH and C1 domains of the Vav1 exchange factor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15498
determination method
IPI
retrieved
8 April 2019
stated in
Sequential phosphorylation of SLP-76 at tyrosine 173 is required for activation of T and mast cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15498
determination method
IPI
retrieved
8 April 2019
stated in
Enhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15498
determination method
IPI
retrieved
8 April 2019
stated in
A protein domain-based interactome network for C. elegans early embryogenesis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15498
determination method
IPI
retrieved
8 April 2019
stated in
Abl-SH3 binding protein 2, 3BP2, interacts with CIN85 and HIP-55
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15498
determination method
IPI
retrieved
8 April 2019
stated in
Abi1/Hssh3bp1 pY213 links Abl kinase signaling to p85 regulatory subunit of PI-3 kinase in regulation of macropinocytosis in LNCaP cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15498
determination method
IPI
retrieved
8 April 2019
stated in
Characterization of VIK-1: a new Vav-interacting Kruppel-like protein
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15498
determination method
IPI
retrieved
8 April 2019
stated in
Regulation of Vav-SLP-76 binding by ZAP-70 and its relevance to TCR zeta/CD3 induction of interleukin-2
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15498
determination method
IPI
retrieved
8 April 2019
stated in
SLP-76 and Vav function in separate, but overlapping pathways to augment interleukin-2 promoter activity
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15498
determination method
IPI
biological process
has part(s)

Identifiers

 
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