Neural retina leucine zipper (Q21112049)

Neural retina-specific leucine zipper protein

1 reference

Basic-leucine zipper domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Basic leucine zipper domain, Maf-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

Maf transcription factor, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

RNA polymerase II cis-regulatory region sequence-specific DNA binding

1 reference

27 March 2018

The basic motif-leucine zipper transcription factor Nrl can positively regulate rhodopsin gene expression

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54845&geneProductId=UniProtKB:P54845

leucine zipper domain binding

1 reference

8 April 2019

The leucine zipper of NRL interacts with the CRX homeodomain. A possible mechanism of transcriptional synergy in rhodopsin regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54845

DNA-binding transcription activator activity, RNA polymerase II-specific

IPI

2 references

27 March 2018

The basic motif-leucine zipper transcription factor Nrl can positively regulate rhodopsin gene expression

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54845&geneProductId=UniProtKB:P54845

8 April 2019

The basic motif-leucine zipper transcription factor Nrl can positively regulate rhodopsin gene expression

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54845

3 references

8 April 2019

The leucine zipper of NRL interacts with the CRX homeodomain. A possible mechanism of transcriptional synergy in rhodopsin regulation

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54845

8 April 2019

Interaction between optineurin and the bZIP transcription factor NRL

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54845

8 April 2019

QRX, a novel homeobox gene, modulates photoreceptor gene expression

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54845

promoter-specific chromatin binding

IPI

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54845

transcription coactivator activity

IEA

1 reference

8 April 2019

Retinopathy mutations in the bZIP protein NRL alter phosphorylation and transcriptional activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54845

sequence-specific DNA binding

IMP

1 reference

27 March 2018

Retinopathy mutations in the bZIP protein NRL alter phosphorylation and transcriptional activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54845&geneProductId=UniProtKB:P54845

DNA-binding transcription factor activity, RNA polymerase II-specific

IDA

3 references

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54845

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54845

8 April 2019

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54845

RNA polymerase II cis-regulatory region sequence-specific DNA binding

ISA

DNA-binding transcription activator activity, RNA polymerase II-specific

IBA

IDA

4 references

10 September 2018

The basic motif-leucine zipper transcription factor Nrl can positively regulate rhodopsin gene expression

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54845&geneProductId=UniProtKB:P54845

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54845&geneProductId=UniProtKB:P54845

7 November 2018

The basic motif-leucine zipper transcription factor Nrl can positively regulate rhodopsin gene expression

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54845&geneProductId=UniProtKB:P54845

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54845&geneProductId=UniProtKB:P54845

DNA-binding transcription factor activity

IBA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54845

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54845

5 references

27 March 2018

The bZIP transcription factor Nrl stimulates rhodopsin promoter activity in primary retinal cell cultures

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54845&geneProductId=UniProtKB:P54845

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54845&geneProductId=UniProtKB:P54845

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54845&geneProductId=UniProtKB:P54845

27 March 2018

Multiple phosphorylated isoforms of NRL are expressed in rod photoreceptors

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54845&geneProductId=UniProtKB:P54845

27 March 2018

Retinopathy mutations in the bZIP protein NRL alter phosphorylation and transcriptional activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54845&geneProductId=UniProtKB:P54845

6 references

8 April 2019

The bZIP transcription factor Nrl stimulates rhodopsin promoter activity in primary retinal cell cultures

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54845

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54845

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54845

8 April 2019

Retinopathy mutations in the bZIP protein NRL alter phosphorylation and transcriptional activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54845

8 April 2019

Multiple phosphorylated isoforms of NRL are expressed in rod photoreceptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54845

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54845

multicellular organism development

IBA

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54845

transcription by RNA polymerase II

IEA

1 reference

8 April 2019

The bZIP transcription factor Nrl stimulates rhodopsin promoter activity in primary retinal cell cultures

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54845

transcription, DNA-templated

TAS

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54845&geneProductId=UniProtKB:P54845

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54845

positive regulation of transcription by RNA polymerase II

IEA

4 references

8 April 2019

Novel p.M96T variant of NRL and shRNA-based suppression and replacement of NRL mutants associated with autosomal dominant retinitis pigmentosa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54845

8 April 2019

Retinopathy mutations in the bZIP protein NRL alter phosphorylation and transcriptional activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54845

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54845

8 April 2019

The basic motif-leucine zipper transcription factor Nrl can positively regulate rhodopsin gene expression

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54845

retinal rod cell development

IDA

Maf transcription factor, N-terminal

1 reference

Basic leucine zipper domain, Maf-type

1 reference

Basic-leucine zipper domain

1 reference