Ubiquitin conjugating enzyme E2 D3 (Q21112096)

http://www.ebi.ac.uk/interpro/protein/P61077

Ubiquitin-conjugating enzyme E2 family

1 reference

based on heuristic

inferred from protein domain or family

Ubiquitin-conjugating enzyme, active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

13 references

31 October 2017

The UbL protein UBTD1 stably interacts with the UBE2D family of E2 ubiquitin conjugating enzymes

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

31 October 2017

Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

31 October 2017

A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

31 October 2017

E2~Ub conjugates regulate the kinase activity of Shigella effector OspG during pathogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

31 October 2017

Physical and functional interactions between ZIP kinase and UbcH5

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

31 October 2017

Towards a proteome-scale map of the human protein–protein interaction network

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

31 October 2017

Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

31 October 2017

A cancer-associated RING finger protein, RNF43, is a ubiquitin ligase that interacts with a nuclear protein, HAP95

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

31 October 2017

FIH Regulates Cellular Metabolism through Hydroxylation of the Deubiquitinase OTUB1

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

31 October 2017

Positive regulation of p53 stability and activity by the deubiquitinating enzyme Otubain 1

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

31 October 2017

Molecular Basis for the Association of Human E4B U Box Ubiquitin Ligase with E2-Conjugating Enzymes UbcH5c and Ubc4

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

31 October 2017

A proteome-scale map of the human interactome network

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

31 October 2017

Identification of an unconventional E3 binding surface on the UbcH5 ~ Ub conjugate recognized by a pathogenic bacterial E3 ligase

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

ubiquitin conjugating enzyme activity

5 references

31 October 2017

Bifunctional apoptosis regulator (BAR), an endoplasmic reticulum (ER)-associated E3 ubiquitin ligase, modulates BI-1 protein stability and function in ER Stress

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

31 October 2017

The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

31 October 2017

Structural and functional characterization of the monomeric U-box domain from E4B

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

31 October 2017

The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

31 October 2017

ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

ubiquitin-protein transferase activity

7 references

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

31 October 2017

Identification of a human ubiquitin-conjugating enzyme that mediates the E6-AP-dependent ubiquitination of p53

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

31 October 2017

Nrdp1-mediated degradation of the gigantic IAP, BRUCE, is a novel pathway for triggering apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

31 October 2017

The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

31 October 2017

MEX is a testis-specific E3 ubiquitin ligase that promotes death receptor-induced apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

31 October 2017

Priming and extending: a UbcH5/Cdc34 E2 handoff mechanism for polyubiquitination on a SCF substrate

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

31 October 2017

UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

extracellular exosome

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

positive regulation of protein targeting to mitochondrion

biological process

1 reference

31 October 2017

High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

protein polyubiquitination

IMP

negative regulation of transcription by RNA polymerase II

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

protein monoubiquitination

1 reference

31 October 2017

Priming and extending: a UbcH5/Cdc34 E2 handoff mechanism for polyubiquitination on a SCF substrate

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

BMP signaling pathway

1 reference

31 October 2017

cellular response to DNA damage stimulus

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

protein K11-linked ubiquitination

1 reference

31 October 2017

The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

TRIF-dependent toll-like receptor signaling pathway

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

protein K48-linked ubiquitination

1 reference

31 October 2017

The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

regulation of transcription from RNA polymerase II promoter in response to hypoxia

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

protein autoubiquitination

1 reference

31 October 2017

Bifunctional apoptosis regulator (BAR), an endoplasmic reticulum (ER)-associated E3 ubiquitin ligase, modulates BI-1 protein stability and function in ER Stress

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

protein ubiquitination

4 references

31 October 2017

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

31 October 2017

UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

31 October 2017

Human ubiquitin-protein ligase Nedd4: expression, subcellular localization and selective interaction with ubiquitin-conjugating enzymes

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

ubiquitin-dependent protein catabolic process

1 reference

31 October 2017

Identification of a family of closely related human ubiquitin conjugating enzymes

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

proteasome-mediated ubiquitin-dependent protein catabolic process

1 reference

31 October 2017

Priming and extending: a UbcH5/Cdc34 E2 handoff mechanism for polyubiquitination on a SCF substrate

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

MyD88-independent toll-like receptor signaling pathway

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077

http://www.uniprot.org/uniprot/P61077.txt?version=131

EC enzyme number

2.3.2.24

1 reference

14 November 2015

has part(s)

Ubiquitin-conjugating enzyme E2

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P61077

Ubiquitin-conjugating enzyme, active site

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P61077

Identifiers

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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13 November 2019

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4 August 2016

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4 August 2016

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4 August 2016

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4 August 2016

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4 August 2016

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4 August 2016

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4 August 2016

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4 August 2016

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4 August 2016