Sperm associated antigen 5 (Q21112651)

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mammalian protein found in Homo sapiens

SPAG5
mitotic spindle associated protein p126
astrin
MAP126
Deepest
sperm-associated antigen 5
Mitotic spindle-associated protein p126
mitotic spindle coiled-coil related protein

Language	Label	Description	Also known as
English	Sperm associated antigen 5	mammalian protein found in Homo sapiens	SPAG5 mitotic spindle associated protein p126 astrin MAP126 Deepest sperm-associated antigen 5 Mitotic spindle-associated protein p126 mitotic spindle coiled-coil related protein

Statements

1 reference

13 November 2019

UniProt protein ID

Sperm-associated antigen 5

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q96R06

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

protein binding

determination method

9 references

8 April 2019

Nuclear Mitotic Apparatus (NuMA) Interacts with and Regulates Astrin at the Mitotic Spindle

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96R06

determination method

8 April 2019

SNM1B/Apollo interacts with astrin and is required for the prophase cell cycle checkpoint

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96R06

determination method

8 April 2019

The astrin-kinastrin/SKAP complex localizes to microtubule plus ends and facilitates chromosome alignment

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96R06

determination method

8 April 2019

Inhibition of mTORC1 by astrin and stress granules prevents apoptosis in cancer cells

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96R06

determination method

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96R06

determination method

8 April 2019

Astrin regulates Aurora-A localization.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96R06

determination method

8 April 2019

CLASP1, astrin and Kif2b form a molecular switch that regulates kinetochore-microtubule dynamics to promote mitotic progression and fidelity

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96R06

determination method

8 April 2019

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96R06

determination method

8 April 2019

Centriolar satellites assemble centrosomal microcephaly proteins to recruit CDK2 and promote centriole duplication

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96R06

determination method

microtubule binding

determination method

1 reference

8 April 2019

Nuclear Mitotic Apparatus (NuMA) Interacts with and Regulates Astrin at the Mitotic Spindle

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96R06

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96R06

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96R06

determination method

microtubule organizing center

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96R06

determination method

centriolar satellite

determination method

1 reference

8 April 2019

Centriolar satellites assemble centrosomal microcephaly proteins to recruit CDK2 and promote centriole duplication

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96R06

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96R06

determination method

chromosome, centromeric region

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96R06

determination method

microtubule plus-end

determination method

1 reference

8 April 2019

The astrin-kinastrin/SKAP complex localizes to microtubule plus ends and facilitates chromosome alignment

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96R06

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96R06

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96R06

determination method

determination method

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96R06

determination method

8 April 2019

Nuclear Mitotic Apparatus (NuMA) Interacts with and Regulates Astrin at the Mitotic Spindle

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96R06

determination method

8 April 2019

The astrin-kinastrin/SKAP complex localizes to microtubule plus ends and facilitates chromosome alignment

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96R06

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96R06

determination method

mitotic spindle pole

determination method

1 reference

8 April 2019

Nuclear Mitotic Apparatus (NuMA) Interacts with and Regulates Astrin at the Mitotic Spindle

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96R06

determination method

biological process

mitotic sister chromatid segregation

determination method

1 reference

8 April 2019

The astrin-kinastrin/SKAP complex localizes to microtubule plus ends and facilitates chromosome alignment

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96R06

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96R06

determination method

spindle organization

determination method

1 reference

8 April 2019

The astrin-kinastrin/SKAP complex localizes to microtubule plus ends and facilitates chromosome alignment

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96R06

determination method

protein localization to centrosome

determination method

1 reference

8 April 2019

Centriolar satellites assemble centrosomal microcephaly proteins to recruit CDK2 and promote centriole duplication

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96R06

determination method

chromosome segregation

determination method

1 reference

8 April 2019

The astrin-kinastrin/SKAP complex localizes to microtubule plus ends and facilitates chromosome alignment

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96R06

determination method

positive regulation of intracellular transport

determination method

1 reference

8 April 2019

Nuclear Mitotic Apparatus (NuMA) Interacts with and Regulates Astrin at the Mitotic Spindle

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96R06

determination method

regulation of metaphase plate congression

determination method

1 reference

8 April 2019

Nuclear Mitotic Apparatus (NuMA) Interacts with and Regulates Astrin at the Mitotic Spindle

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96R06

determination method

positive regulation of spindle assembly

determination method

1 reference

8 April 2019

Nuclear Mitotic Apparatus (NuMA) Interacts with and Regulates Astrin at the Mitotic Spindle

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96R06

determination method

Identifiers

RefSeq protein ID

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000323300

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000323300

ENSP00000444223

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000444223

ENSP00000462663

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000462663

ENSP00000463095

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000463095

ENSP00000464280

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000464280

ENSP00000464400

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000464400

ENSP00000464474

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000464474

ENSP00000466021

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000466021

ENSP00000466061

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000466061

Sitelinks

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Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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