ATP binding cassette subfamily D member 3 (Q21113663)

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mammalian protein found in Homo sapiens

70 kDa peroxisomal membrane protein
PMP70
Peroxisomal membrane protein-1 (70kD)
dJ824O18.1 (ATP-binding cassette, sub-family D (ALD), member 3 (PMP70, PXMP1))
ATP-binding cassette, sub-family D (ALD), member 3
ABCD3
ATP-binding cassette sub-family D member 3
peroxisomal membrane protein 1 (70kD, Zellweger syndrome)

Language	Label	Description	Also known as
English	ATP binding cassette subfamily D member 3	mammalian protein found in Homo sapiens	70 kDa peroxisomal membrane protein PMP70 Peroxisomal membrane protein-1 (70kD) dJ824O18.1 (ATP-binding cassette, sub-family D (ALD), member 3 (PMP70, PXMP1)) ATP-binding cassette, sub-family D (ALD), member 3 ABCD3 ATP-binding cassette sub-family D member 3 peroxisomal membrane protein 1 (70kD, Zellweger syndrome)

Statements

1 reference

13 November 2019

UniProt protein ID

ABC transporter type 1, transmembrane domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P28288

P-loop containing nucleoside triphosphate hydrolase

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P28288

Peroxysomal Fatty Acyl CoA Transporter

1 reference

Transporter Classification Database ID

2 October 2019

based on heuristic

hierarchical database ID heuristic

1 reference

based on heuristic

inferred from protein domain or family

ABC transporter-like, protein family

1 reference

based on heuristic

inferred from protein domain or family

ABC transporter type 1, transmembrane domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

ABC transporter, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

ATPase-coupled transmembrane transporter activity

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

nucleotide binding

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

protein self-association

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

protein binding

determination method

11 references

9 May 2019

Human adrenoleukodystrophy protein and related peroxisomal ABC transporters interact with the peroxisomal assembly protein PEX19p

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

9 May 2019

PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

9 May 2019

Role of Pex19p in the targeting of PMP70 to peroxisome

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

9 May 2019

Two splice variants of human PEX19 exhibit distinct functions in peroxisomal assembly

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

9 May 2019

Live cell FRET microscopy: homo- and heterodimerization of two human peroxisomal ABC transporters, the adrenoleukodystrophy protein (ALDP, ABCD1) and PMP70 (ABCD3)

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

9 May 2019

Targeting elements in the amino-terminal part direct the human 70-kDa peroxisomal integral membrane protein (PMP70) to peroxisomes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

9 May 2019

Two different targeting signals direct human peroxisomal membrane protein 22 to peroxisomes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

9 May 2019

Structural basis for docking of peroxisomal membrane protein carrier Pex19p onto its receptor Pex3p

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

9 May 2019

PEX19 is a predominantly cytosolic chaperone and import receptor for class 1 peroxisomal membrane proteins

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

9 May 2019

PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

9 May 2019

Homo- and heterodimerization of peroxisomal ATP-binding cassette half-transporters

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

determination method

4 references

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

9 May 2019

Characterization and functional analysis of the nucleotide binding fold in human peroxisomal ATP binding cassette transporters

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

long-chain fatty acid transporter activity

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

intracellular membrane-bounded organelle

determination method

1 reference

9 May 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

peroxisomal membrane

determination method

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

9 May 2019

Live cell FRET microscopy: homo- and heterodimerization of two human peroxisomal ABC transporters, the adrenoleukodystrophy protein (ALDP, ABCD1) and PMP70 (ABCD3)

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

determination method

12 references

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

9 May 2019

Adrenoleukodystrophy: subcellular localization and degradation of adrenoleukodystrophy protein (ALDP/ABCD1) with naturally occurring missense mutations

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

9 May 2019

Pex3p-dependent peroxisomal biogenesis initiates in the endoplasmic reticulum of human fibroblasts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

9 May 2019

Suppression of peroxisomal membrane protein defects by peroxisomal ATP binding cassette (ABC) proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

9 May 2019

PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

9 May 2019

Role of Pex19p in the targeting of PMP70 to peroxisome

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

9 May 2019

Targeting elements in the amino-terminal part direct the human 70-kDa peroxisomal integral membrane protein (PMP70) to peroxisomes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

9 May 2019

Multiple organelle-targeting signals in the N-terminal portion of peroxisomal membrane protein PMP70

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

9 May 2019

Peroxisome synthesis in the absence of preexisting peroxisomes

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

9 May 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

peroxisomal matrix

determination method

1 reference

9 May 2019

Restoration of PEX2 peroxisome assembly defects by overexpression of PMP70

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

mitochondrial inner membrane

determination method

1 reference

26 September 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28288&geneProductId=UniProtKB:P28288

determination method

biological process

long-chain fatty acid import into peroxisome

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

response to organic cyclic compound

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

fatty acid biosynthetic process

determination method

1 reference

9 May 2019

A novel bile acid biosynthesis defect due to a deficiency of peroxisomal ABCD3

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

very long-chain fatty acid catabolic process

determination method

1 reference

9 May 2019

Suppression of peroxisomal membrane protein defects by peroxisomal ATP binding cassette (ABC) proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

fatty acid beta-oxidation

determination method

1 reference

9 May 2019

Suppression of peroxisomal membrane protein defects by peroxisomal ATP binding cassette (ABC) proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28288

determination method

determination method

2 references

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000326880

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000326880

ENSP00000359233

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000359233

ENSP00000497921

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000497921

Transporter Classification Database ID

2 references

Transporter Classification database

13 March 2020

Transporter Classification database

29 April 2020

Sitelinks

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Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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