SH3 and PX domains 2A (Q21113815)

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mammalian protein found in Homo sapiens

SH3 multiple domains protein 1
adapter protein TKS5
adaptor protein TKS5
SH3 multiple domains 1
five SH3 domain-containing protein
tyrosine kinase substrate with five SH3 domains
SH3PXD2A
SH3 and PX domain-containing protein 2A

Language	Label	Description	Also known as
English	SH3 and PX domains 2A	mammalian protein found in Homo sapiens	SH3 multiple domains protein 1 adapter protein TKS5 adaptor protein TKS5 SH3 multiple domains 1 five SH3 domain-containing protein tyrosine kinase substrate with five SH3 domains SH3PXD2A SH3 and PX domain-containing protein 2A

Statements

1 reference

13 November 2019

UniProt protein ID

SH3-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q5TCZ1

PX domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q5TCZ1

SH3 and PX domain-containing protein 2A

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q5TCZ1

Phox homologous domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

SH3PXD2A, SH3 domain 5, protein family

1 reference

based on heuristic

inferred from protein domain or family

SH3PXD2A, SH3 domain 4, protein family

1 reference

based on heuristic

inferred from protein domain or family

SH3PXD2A, SH3 domain 2, protein family

1 reference

based on heuristic

inferred from protein domain or family

SH3PXD2, PX domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

SH3PXD2A, SH3 domain 3, protein family

1 reference

based on heuristic

inferred from protein domain or family

SH3PXD2A, SH3 domain 1, protein family

1 reference

based on heuristic

inferred from protein domain or family

SH3 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

protein binding

determination method

3 references

8 April 2019

Direct interaction between Tks proteins and the N-terminal proline-rich region (PRR) of NoxA1 mediates Nox1-dependent ROS generation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TCZ1

determination method

8 April 2019

Novel p47(phox)-related organizers regulate localized NADPH oxidase 1 (Nox1) activity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TCZ1

determination method

8 April 2019

Identification of preferred protein interactions by phage-display of the human Src homology-3 proteome

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TCZ1

determination method

superoxide-generating NADPH oxidase activator activity

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TCZ1

determination method

phosphatidylinositol binding

determination method

protease binding

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TCZ1

determination method

phosphatidylinositol-4,5-bisphosphate binding

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TCZ1

determination method

phosphatidylinositol-5-phosphate binding

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TCZ1

determination method

phosphatidylinositol-3-phosphate binding

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TCZ1

determination method

phosphatidylinositol-3,4-bisphosphate binding

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TCZ1

determination method

phosphatidylinositol-4-phosphate binding

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TCZ1

determination method

determination method

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TCZ1

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TCZ1

determination method

8 April 2019

A role for the podosome/invadopodia scaffold protein Tks5 in tumor growth in vivo

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TCZ1

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TCZ1

determination method

cell projection

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TCZ1

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TCZ1

determination method

biological process

osteoclast fusion

determination method

1 reference

8 April 2019

Tks5-dependent formation of circumferential podosomes/invadopodia mediates cell-cell fusion

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TCZ1

determination method

superoxide metabolic process

determination method

reactive oxygen species metabolic process

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TCZ1

determination method

positive regulation of catalytic activity

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TCZ1

determination method

podosome assembly

determination method

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q5TCZ1&geneProductId=UniProtKB:Q5TCZ1

determination method

extracellular matrix organization

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TCZ1

determination method

superoxide metabolic process

determination method

3 references

8 April 2019

Direct interaction between Tks proteins and the N-terminal proline-rich region (PRR) of NoxA1 mediates Nox1-dependent ROS generation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TCZ1

determination method

8 April 2019

Novel p47(phox)-related organizers regulate localized NADPH oxidase 1 (Nox1) activity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TCZ1

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TCZ1

determination method

Phox homologous domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q5TCZ1

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q5TCZ1

SH3PXD2A, SH3 domain 1

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q5TCZ1

SH3PXD2A, SH3 domain 2

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q5TCZ1

SH3PXD2A, SH3 domain 3

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q5TCZ1

SH3PXD2A, SH3 domain 4

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q5TCZ1

SH3PXD2A, SH3 domain 5

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q5TCZ1

SH3PXD2, PX domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q5TCZ1

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000348215

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000348215

ENSP00000358789

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000358789

ENSP00000395781

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000395781

PDB structure ID

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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