Angiotensin II receptor type 2 (Q21113831)

http://www.ebi.ac.uk/interpro/protein/P50052

GPCR, rhodopsin-like, 7TM, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

signal transducer activity

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50052&geneProductId=UniProtKB:P50052

receptor antagonist activity

1 reference

8 April 2019

Angiotensin type 2 receptor in resistance arteries of type 2 diabetic hypertensive patients

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

peptide hormone binding

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50052&geneProductId=UniProtKB:P50052

3 references

8 April 2019

Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

8 April 2019

Tissue inhibitor of metalloproteinases-3 interacts with angiotensin II type 2 receptor and additively inhibits angiogenesis

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

8 April 2019

Analysis of functional domains of angiotensin II type 2 receptor involved in apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

angiotensin type II receptor activity

IPI

4 references

7 November 2018

Photoaffinity labeling of subtype 2 angiotensin receptor of human myometrium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50052&geneProductId=UniProtKB:P50052

7 November 2018

Analysis of functional domains of angiotensin II type 2 receptor involved in apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50052&geneProductId=UniProtKB:P50052

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50052&geneProductId=UniProtKB:P50052

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50052&geneProductId=UniProtKB:P50052

transcription factor binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

G protein-coupled receptor activity

IBA

angiotensin type II receptor activity

5 references

8 April 2019

Photoaffinity labeling of subtype 2 angiotensin receptor of human myometrium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

8 April 2019

Analysis of functional domains of angiotensin II type 2 receptor involved in apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

perinuclear region of cytoplasm

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50052&geneProductId=UniProtKB:P50052

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

regulation of metanephros size

IBA

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

positive regulation of metanephric glomerulus development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

regulation of apoptotic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

positive regulation of branching involved in ureteric bud morphogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

dopamine biosynthetic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

positive regulation of nitric oxide biosynthetic process

1 reference

8 April 2019

Angiotensin II stimulates endothelial NO synthase phosphorylation in thoracic aorta of mice with abdominal aortic banding via type 2 receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

negative regulation of norepinephrine secretion

IC

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

cellular sodium ion homeostasis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

renin-angiotensin regulation of aldosterone production

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

cellular response to dexamethasone stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

1 reference

8 April 2019

AGTR2 mutations in X-linked mental retardation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure

NAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

brain renin-angiotensin system

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

regulation of blood pressure

1 reference

8 April 2019

Behavioural and cardiovascular effects of disrupting the angiotensin II type-2 receptor in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

negative regulation of icosanoid secretion

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

positive regulation of extrinsic apoptotic signaling pathway

1 reference

8 April 2019

Analysis of functional domains of angiotensin II type 2 receptor involved in apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

IMP

aldosterone secretion

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

positive regulation of cell population proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

positive regulation of transcription, DNA-templated

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

negative regulation of blood vessel endothelial cell migration

1 reference

8 April 2019

Angiotensin II type 2 receptor-mediated gene expression profiling in human coronary artery endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

negative regulation of neurotrophin TRK receptor signaling pathway

NAS

1 reference

8 April 2019

Analysis of functional domains of angiotensin II type 2 receptor involved in apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

response to organonitrogen compound

IMP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

cerebellar cortex development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

negative regulation of fibroblast proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

Cross-talk between angiotensin II receptor types 1 and 2: potential role in vascular remodeling in humans

blood vessel remodeling

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

cell growth involved in cardiac muscle cell development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

negative regulation of cell growth

1 reference

8 April 2019

Cross-talk between angiotensin II receptor types 1 and 2: potential role in vascular remodeling in humans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

positive regulation of phosphoprotein phosphatase activity

1 reference

8 April 2019

Analysis of functional domains of angiotensin II type 2 receptor involved in apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

positive regulation of renal sodium excretion

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

nitric oxide mediated signal transduction

IC

angiotensin-activated signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

extracellular negative regulation of signal transduction

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50052&geneProductId=UniProtKB:P50052

blood vessel diameter maintenance

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

G protein-coupled receptor signaling pathway

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

8 April 2019

Analysis of functional domains of angiotensin II type 2 receptor involved in apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

regulation of protein import into nucleus

IC

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

inflammatory response

IBA

negative regulation of signaling receptor activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50052

physically interacts with

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

8374

language of work or name

17 August 2016

1 reference

Open Targets Platform

retrieved

14 August 2023

https://platform.opentargets.org/drug/CHEMBL34124

has part(s)

GPCR, rhodopsin-like, 7TM

1 reference

stated in

InterPro Release 71.0