CD3g molecule (Q21114006)

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mammalian protein found in Homo sapiens

CD3g molecule, gamma (CD3-TCR complex)
T-cell receptor T3 gamma chain
T-cell antigen receptor complex, gamma subunit of T3
CD3G
CD3g antigen, gamma polypeptide (TiT3 complex)
CD3g molecule, epsilon (CD3-TCR complex)
T-cell surface glycoprotein CD3 gamma chain

Language	Label	Description	Also known as
English	CD3g molecule	mammalian protein found in Homo sapiens	CD3g molecule, gamma (CD3-TCR complex) T-cell receptor T3 gamma chain T-cell antigen receptor complex, gamma subunit of T3 CD3G CD3g antigen, gamma polypeptide (TiT3 complex) CD3g molecule, epsilon (CD3-TCR complex) T-cell surface glycoprotein CD3 gamma chain

Statements

1 reference

13 November 2019

UniProt protein ID

CD3 protein, epsilon/gamma/delta subunit

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P09693

Immunoglobulin-like fold

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P09693

Immunoglobulin-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P09693

Immunoglobulin subtype 2, protein family

1 reference

based on heuristic

inferred from protein domain or family

CD3 gamma/delta subunit, Ig-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Phosphorylated immunoreceptor signalling ITAM, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

signaling receptor complex adaptor activity

determination method

1 reference

8 April 2019

TCR dynamics in human mature T lymphocytes lacking CD3 gamma

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09693

determination method

T cell receptor binding

determination method

1 reference

8 April 2019

Fourteen years' follow-up of an autoimmune patient lacking the CD3 gamma subunit of the T-lymphocyte receptor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09693

determination method

protein heterodimerization activity

determination method

1 reference

8 April 2019

Assembly of the TCR/CD3 complex: CD3 epsilon/delta and CD3 epsilon/gamma dimers associate indistinctly with both TCR alpha and TCR beta chains. Evidence for a double TCR heterodimer model

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09693

determination method

protein homodimerization activity

determination method

1 reference

8 April 2019

Homooligomerization of the cytoplasmic domain of the T cell receptor zeta chain and of other proteins containing the immunoreceptor tyrosine-based activation motif

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09693

determination method

transmembrane signaling receptor activity

determination method

3 references

8 April 2019

TCR dynamics in human mature T lymphocytes lacking CD3 gamma

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09693

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09693

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09693

determination method

integral component of membrane

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09693

determination method

alpha-beta T cell receptor complex

determination method

1 reference

24 April 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09693&geneProductId=UniProtKB:P09693

determination method

integral component of plasma membrane

determination method

1 reference

8 April 2019

Assembly of the TCR/CD3 complex: CD3 epsilon/delta and CD3 epsilon/gamma dimers associate indistinctly with both TCR alpha and TCR beta chains. Evidence for a double TCR heterodimer model

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09693

determination method

T cell receptor complex

determination method

1 reference

8 April 2019

Assembly of the TCR/CD3 complex: CD3 epsilon/delta and CD3 epsilon/gamma dimers associate indistinctly with both TCR alpha and TCR beta chains. Evidence for a double TCR heterodimer model

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09693

determination method

determination method

2 references

clathrin-coated vesicle membrane

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09693

determination method

plasma membrane

determination method

2 references

external side of plasma membrane

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09693

determination method

biological process

protein transport

determination method

1 reference

8 April 2019

TCR dynamics in human mature T lymphocytes lacking CD3 gamma

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09693

determination method

establishment or maintenance of cell polarity

determination method

1 reference

8 April 2019

Contribution of CD3 gamma to TCR regulation and signaling in human mature T lymphocytes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09693

determination method

T cell receptor signaling pathway

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09693

determination method

regulation of lymphocyte apoptotic process

determination method

1 reference

8 April 2019

Contribution of CD3 gamma to TCR regulation and signaling in human mature T lymphocytes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09693

determination method

T cell activation

determination method

1 reference

8 April 2019

Contribution of CD3 gamma to TCR regulation and signaling in human mature T lymphocytes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09693

determination method

Fc-gamma receptor signaling pathway involved in phagocytosis

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09693

determination method

regulation of immune response

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09693

determination method

membrane organization

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09693

determination method

protein homooligomerization

determination method

1 reference

8 April 2019

Homooligomerization of the cytoplasmic domain of the T cell receptor zeta chain and of other proteins containing the immunoreceptor tyrosine-based activation motif

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09693

determination method

adaptive immune response

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09693

determination method

immune system process

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09693

determination method

protein-containing complex assembly

determination method

1 reference

8 April 2019

TCR dynamics in human mature T lymphocytes lacking CD3 gamma

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09693

determination method

cell surface receptor signaling pathway

determination method

3 references

8 April 2019

Contribution of CD3 gamma to TCR regulation and signaling in human mature T lymphocytes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09693

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09693

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09693

determination method

T cell differentiation

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09693

determination method

positive thymic T cell selection

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09693

determination method

positive regulation of signal transduction

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09693

determination method

CD3 gamma/delta subunit, Ig-like domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P09693

immunoglobulin subtype 2

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P09693

Phosphorylated immunoreceptor signalling ITAM

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P09693

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000431445

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000431445

ENSP00000292144

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000292144

ENSP00000376621

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000376621

ENSP00000498162

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000498162

PDB structure ID

1 reference

5 January 2016

http://www.uniprot.org/uniprot/P09693.txt?version=154

Sitelinks

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Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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