ETS transcription factor ELK1 (Q21114374)

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mammalian protein found in Homo sapiens

ELK1, member of ETS oncogene family
ELK1
ETS-like gene 1
tyrosine kinase (ELK1) oncogene
ELK1, ETS transcription factor
ETS domain-containing protein Elk-1

Language	Label	Description	Also known as
English	ETS transcription factor ELK1	mammalian protein found in Homo sapiens	ELK1, member of ETS oncogene family ELK1 ETS-like gene 1 tyrosine kinase (ELK1) oncogene ELK1, ETS transcription factor ETS domain-containing protein Elk-1

Statements

1 reference

13 November 2019

UniProt protein ID

winged helix DNA-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19419

Winged helix-like DNA-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19419

ETS transcription factor family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

sequence-specific DNA binding

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

DNA-binding transcription factor activity

determination method or standard

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

8 April 2019

Isoforms of the Ets transcription factor NERF/ELF-2 physically interact with AML1 and mediate opposing effects on AML1-mediated transcription of the B cell-specific blk gene

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

DNA-binding transcription activator activity, RNA polymerase II-specific

determination method or standard

2 references

10 September 2018

Ets transcription factors ER81 and Elk1 regulate the transcription of the human presenilin 1 gene promoter

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19419&geneProductId=UniProtKB:P19419

determination method or standard

8 April 2019

Ets transcription factors ER81 and Elk1 regulate the transcription of the human presenilin 1 gene promoter

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

chromatin binding

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

protein binding

determination method or standard

5 references

8 April 2019

Rev7/MAD2B links c-Jun N-terminal protein kinase pathway signaling to activation of the transcription factor Elk-1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

8 April 2019

Ubc9 acetylation modulates distinct SUMO target modification and hypoxia response

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

8 April 2019

The tyrosine kinase Syk regulates TPL2 activation signals

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

8 April 2019

Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

8 April 2019

An extended consensus motif enhances the specificity of substrate modification by SUMO

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

double-stranded DNA binding

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

DNA-binding transcription factor activity, RNA polymerase II-specific

determination method or standard

3 references

27 March 2018

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19419&geneProductId=UniProtKB:P19419

determination method or standard

27 March 2018

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19419&geneProductId=UniProtKB:P19419

determination method or standard

27 March 2018

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19419&geneProductId=UniProtKB:P19419

determination method or standard

DNA-binding transcription factor activity, RNA polymerase II-specific

determination method or standard

4 references

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

8 April 2019

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

determination method or standard

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

determination method or standard

4 references

27 March 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19419&geneProductId=UniProtKB:P19419

determination method or standard

27 March 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19419&geneProductId=UniProtKB:P19419

determination method or standard

27 March 2018

Phosphorylation and acetylation of histone H3 and autoregulation by early growth response 1 mediate interleukin 1beta induction of early growth response 1 transcription

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19419&geneProductId=UniProtKB:P19419

determination method or standard

27 March 2018

Isoforms of the Ets transcription factor NERF/ELF-2 physically interact with AML1 and mediate opposing effects on AML1-mediated transcription of the B cell-specific blk gene

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19419&geneProductId=UniProtKB:P19419

determination method or standard

determination method or standard

5 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

8 April 2019

Phosphorylation and acetylation of histone H3 and autoregulation by early growth response 1 mediate interleukin 1beta induction of early growth response 1 transcription

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

8 April 2019

Isoforms of the Ets transcription factor NERF/ELF-2 physically interact with AML1 and mediate opposing effects on AML1-mediated transcription of the B cell-specific blk gene

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

biological process

cell differentiation

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

response to light stimulus

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

cellular response to testosterone stimulus

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

positive regulation of neuron death

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

transcription, DNA-templated

determination method or standard

1 reference

27 March 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19419&geneProductId=UniProtKB:P19419

determination method or standard

positive regulation of transcription, DNA-templated

determination method or standard

3 references

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

8 April 2019

Rev7/MAD2B links c-Jun N-terminal protein kinase pathway signaling to activation of the transcription factor Elk-1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

8 April 2019

Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

cellular response to gamma radiation

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

cellular response to lipid

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

positive regulation of transcription by RNA polymerase II

determination method or standard

4 references

8 April 2019

Oncogenic Ras and B-Raf proteins positively regulate death receptor 5 expression through co-activation of ERK and JNK signaling

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

8 April 2019

Isoforms of the Ets transcription factor NERF/ELF-2 physically interact with AML1 and mediate opposing effects on AML1-mediated transcription of the B cell-specific blk gene

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

8 April 2019

Ets transcription factors ER81 and Elk1 regulate the transcription of the human presenilin 1 gene promoter

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

transcription by RNA polymerase II

determination method or standard

1 reference

27 March 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19419&geneProductId=UniProtKB:P19419

determination method or standard

regulation of transcription by RNA polymerase II

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19419

determination method or standard

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19419

Identifiers

MeSH descriptor ID

subject named as

ets-Domain Protein Elk-1

0 references

D12.776.260.665.600.100

0 references

D12.776.624.664.700.175.600.100

0 references

D12.776.930.720.600.100

0 references

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000247161

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000247161

ENSP00000345585

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000345585

ENSP00000366182

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000366182

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

25 May 2023

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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