Fem-1 homolog B (Q21114499)

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mammalian protein found in Homo sapiens

FEM1-beta
protein fem-1 homolog B
FEM1B
fem-1-like in apoptotic pathway protein alpha
F1A-alpha
FEM-1-like death receptor binding protein
fem-1-like death receptor-binding protein alpha

Language	Label	Description	Also known as
English	Fem-1 homolog B	mammalian protein found in Homo sapiens	FEM1-beta protein fem-1 homolog B FEM1B fem-1-like in apoptotic pathway protein alpha F1A-alpha FEM-1-like death receptor binding protein fem-1-like death receptor-binding protein alpha

Statements

1 reference

13 November 2019

UniProt protein ID

Ankyrin repeat-containing domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9UK73

Ankyrin repeat-containing domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Ankyrin repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

death receptor binding

determination method

protein binding

determination method

5 references

8 April 2019

The Caenorhabditis elegans sex-determining protein FEM-2 and its human homologue, hFEM-2, are Ca2+/calmodulin-dependent protein kinase phosphatases that promote apoptosis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UK73

determination method

8 April 2019

Posttranslational hydroxylation of ankyrin repeats in IkappaB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UK73

determination method

8 April 2019

Human FEM1B is required for Rad9 recruitment and CHK1 activation in response to replication stress

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UK73

determination method

8 April 2019

The Caenorhabditis elegans sex-determining protein FEM-2 and its human homologue, hFEM-2, are Ca2+/calmodulin-dependent protein kinase phosphatases that promote apoptosis

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UK73

determination method

8 April 2019

Posttranslational hydroxylation of ankyrin repeats in IkappaB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UK73

determination method

ubiquitin-protein transferase activity

determination method

1 reference

8 April 2019

VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UK73

determination method

determination method

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UK73

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UK73

determination method

8 April 2019

Human FEM1B is required for Rad9 recruitment and CHK1 activation in response to replication stress

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UK73

determination method

determination method

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UK73

determination method

determination method

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UK73

determination method

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UK73

determination method

biological process

regulation of extrinsic apoptotic signaling pathway via death domain receptors

determination method

1 reference

8 April 2019

F1Aalpha, a death receptor-binding protein homologous to the Caenorhabditis elegans sex-determining protein, FEM-1, is a caspase substrate that mediates apoptosis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UK73

determination method

regulation of DNA damage checkpoint

determination method

1 reference

8 April 2019

Human FEM1B is required for Rad9 recruitment and CHK1 activation in response to replication stress

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UK73

determination method

branching involved in prostate gland morphogenesis

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UK73

determination method

regulation of ubiquitin-protein transferase activity

determination method

1 reference

8 April 2019

VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UK73

determination method

epithelial cell maturation

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UK73

determination method

epithelial cell maturation involved in prostate gland development

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UK73

determination method

post-translational protein modification

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UK73

determination method

ankyrin repeat-containing domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9UK73

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9UK73

Identifiers

RefSeq protein ID

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000307298

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000307298

ENSP00000456968

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000456968

ENSP00000457002

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000457002

ENSP00000457342

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000457342

Sitelinks

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Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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