Fli-1 proto-oncogene, ETS transcription factor (Q21114539)

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mammalian protein found in Homo sapiens

Ewing sarcoma breakpoint region 2
FLI1
Friend leukemia virus integration 1
Proto-oncogene Fli-1
transcription factor ERGB
Friend leukemia integration 1 transcription factor
Proto-Oncogene Protein c-fli-1

Language	Label	Description	Also known as
English	Fli-1 proto-oncogene, ETS transcription factor	mammalian protein found in Homo sapiens	Ewing sarcoma breakpoint region 2 FLI1 Friend leukemia virus integration 1 Proto-oncogene Fli-1 transcription factor ERGB Friend leukemia integration 1 transcription factor Proto-Oncogene Protein c-fli-1

Statements

1 reference

13 November 2019

UniProt protein ID

Winged helix DNA-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q01543

Winged helix-like DNA-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q01543

Friend leukemia integration 1 transcription factor

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q01543

Sterile alpha motif/pointed domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q01543

ETS transcription factor family

1 reference

based on heuristic

inferred from protein domain or family

Friend leukemia integration 1 transcription factor, pointed domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Pointed domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

protein binding

determination method

1 reference

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01543

determination method

RNA polymerase II cis-regulatory region sequence-specific DNA binding

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01543

determination method

chromatin binding

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01543

determination method

DNA-binding transcription factor activity, RNA polymerase II-specific

determination method

4 references

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01543

determination method

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01543

determination method

8 April 2019

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01543

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01543

determination method

determination method

6 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01543

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01543

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01543

determination method

8 April 2019

Macrothrombocytopenia and dense granule deficiency associated with FLI1 variants: ultrastructural and pathogenic features.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01543

determination method

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01543

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01543

determination method

determination method

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01543

determination method

determination method

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01543

determination method

biological process

megakaryocyte development

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01543

determination method

positive regulation of transcription by RNA polymerase II

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01543

determination method

transcription by RNA polymerase II

determination method

1 reference

27 March 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01543&geneProductId=UniProtKB:Q01543

determination method

determination method

1 reference

8 April 2019

Hemorrhage, impaired hematopoiesis, and lethality in mouse embryos carrying a targeted disruption of the Fli1 transcription factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01543

determination method

regulation of transcription by RNA polymerase II

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01543

determination method

cell differentiation

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01543

determination method

blood circulation

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01543

determination method

transcription, DNA-templated

determination method

1 reference

27 March 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01543&geneProductId=UniProtKB:Q01543

determination method

positive regulation of transcription, DNA-templated

determination method

1 reference

8 April 2019

Paris-Trousseau thrombocytopenia is phenocopied by the autosomal recessive inheritance of a DNA-binding domain mutation in FLI1.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01543

determination method

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q01543

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q01543

Friend leukemia integration 1 transcription factor, pointed domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q01543

Identifiers

MeSH descriptor ID

subject named as

Proto-Oncogene Protein c-fli-1

0 references

D12.776.260.665.400

0 references

D12.776.624.664.700.175.400

0 references

D12.776.930.720.400

0 references

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000281428

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000281428

ENSP00000339627

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000339627

ENSP00000432950

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000432950

ENSP00000433488

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000433488

ENSP00000399985

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000399985

ENSP00000476428

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000476428

ENSP00000477262

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000477262

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

25 May 2023

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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