RAS like proto-oncogene A (Q21114964)

From Wikidata

Jump to navigation Jump to search

mammalian protein found in Homo sapiens

ras-related protein Ral-A
ras related GTP binding protein A
RALA
RALA Ras like proto-oncogene A
RAS-like protein A
Ras family small GTP binding protein RALA
v-ral simian leukemia viral oncogene homolog A (ras related)

Language	Label	Description	Also known as
English	RAS like proto-oncogene A	mammalian protein found in Homo sapiens	ras-related protein Ral-A ras related GTP binding protein A RALA RALA Ras like proto-oncogene A RAS-like protein A Ras family small GTP binding protein RALA v-ral simian leukemia viral oncogene homolog A (ras related)

Statements

1 reference

13 November 2019

UniProt protein ID

Ras-related protein Ral

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P11233

P-loop containing nucleoside triphosphate hydrolase

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P11233

Small GTP-binding protein domain family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

Edg-2 lysophosphatidic acid receptor binding

determination method

1 reference

9 May 2019

Dual regulation of lysophosphatidic acid (LPA1) receptor signalling by Ral and GRK

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

nucleotide binding

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

determination method

1 reference

8 April 2019

The deubiquitylase USP33 discriminates between RALB functions in autophagy and innate immune response

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

determination method

1 reference

9 May 2019

The deubiquitylase USP33 discriminates between RALB functions in autophagy and innate immune response

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

determination method

1 reference

9 May 2019

The deubiquitylase USP33 discriminates between RALB functions in autophagy and innate immune response

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

determination method

4 references

8 April 2019

Identification of the ral and rac1 gene products, low molecular mass GTP-binding proteins from human platelets

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

8 April 2019

The deubiquitylase USP33 discriminates between RALB functions in autophagy and innate immune response

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

protein binding

determination method

10 references

9 May 2019

CEACAM1 functionally interacts with filamin A and exerts a dual role in the regulation of cell migration

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

9 May 2019

The deubiquitylase USP33 discriminates between RALB functions in autophagy and innate immune response

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

9 May 2019

Bridging Ral GTPase to Rho pathways. RLIP76, a Ral effector with CDC42/Rac GTPase-activating protein activity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

9 May 2019

Dual regulation of lysophosphatidic acid (LPA1) receptor signalling by Ral and GRK

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

9 May 2019

Surface PD-L1, E-cadherin, CD24, and VEGFR2 as markers of epithelial cancer stem cells associated with rapid tumorigenesis

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

9 May 2019

Structural basis of the interaction between RalA and Sec5, a subunit of the sec6/8 complex

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

9 May 2019

The tumor suppressor PP2A Abeta regulates the RalA GTPase

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

9 May 2019

RalB and the exocyst mediate the cellular starvation response by direct activation of autophagosome assembly

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

9 May 2019

Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

9 May 2019

The small GTPase RalA targets filamin to induce filopodia

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

GTPase activity

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

ubiquitin protein ligase binding

determination method

1 reference

9 May 2019

The deubiquitylase USP33 discriminates between RALB functions in autophagy and innate immune response

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

determination method

5 references

9 May 2019

Identification of the ral and rac1 gene products, low molecular mass GTP-binding proteins from human platelets

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

9 May 2019

The deubiquitylase USP33 discriminates between RALB functions in autophagy and innate immune response

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

determination method

1 reference

31 October 2017

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11233&geneProductId=UniProtKB:P11233

determination method

determination method

1 reference

31 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11233&geneProductId=UniProtKB:P11233

determination method

plasma membrane

determination method

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

8 April 2019

Geranylgeranyltransferase I inhibitors target RalB to inhibit anchorage-dependent growth and induce apoptosis and RalA to inhibit anchorage-independent growth

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

endocytic vesicle

determination method

1 reference

9 May 2019

Dual regulation of lysophosphatidic acid (LPA1) receptor signalling by Ral and GRK

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

extracellular exosome

determination method

4 references

31 October 2017

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11233&geneProductId=UniProtKB:P11233

determination method

31 October 2017

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11233&geneProductId=UniProtKB:P11233

determination method

31 October 2017

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11233&geneProductId=UniProtKB:P11233

determination method

31 October 2017

Large-scale proteomics and phosphoproteomics of urinary exosomes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11233&geneProductId=UniProtKB:P11233

determination method

cytoplasmic vesicle membrane

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

determination method

1 reference

9 May 2019

Dual regulation of lysophosphatidic acid (LPA1) receptor signalling by Ral and GRK

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

determination method

1 reference

9 May 2019

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

extracellular exosome

determination method

4 references

9 May 2019

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

9 May 2019

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

9 May 2019

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

9 May 2019

Large-scale proteomics and phosphoproteomics of urinary exosomes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

plasma membrane

determination method

4 references

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

9 May 2019

Geranylgeranyltransferase I inhibitors target RalB to inhibit anchorage-dependent growth and induce apoptosis and RalA to inhibit anchorage-independent growth

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

biological process

actin cytoskeleton reorganization

determination method

1 reference

9 May 2019

The small GTPase RalA targets filamin to induce filopodia

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

determination method

1 reference

9 May 2019

Involvement of Ras and Ral in chemotactic migration of skeletal myoblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

neural tube closure

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

membrane organization

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

determination method

1 reference

31 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11233&geneProductId=UniProtKB:P11233

determination method

positive regulation of filopodium assembly

determination method

1 reference

9 May 2019

The small GTPase RalA targets filamin to induce filopodia

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

signal transduction

determination method

3 references

9 May 2019

Involvement of Ras and Ral in chemotactic migration of skeletal myoblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

9 May 2019

Identification of the ral and rac1 gene products, low molecular mass GTP-binding proteins from human platelets

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

Ras protein signal transduction

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

interleukin-12-mediated signaling pathway

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

regulation of exocytosis

determination method

3 references

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

9 May 2019

RalA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11233

determination method

physically interacts with

determination method

Affinity Capture-MS

1 reference

https://thebiogrid.org/news/227

19 April 2020

A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing

small GTP-binding protein domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P11233

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000005257

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000005257

ENSP00000388975

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000388975

ENSP00000413227

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000413227

PDB structure ID

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q21114964&oldid=2022960467"