Centrosomal protein 250 (Q21115402)

mammalian protein found in Homo sapiens

250 kDa centrosomal protein
C-Nap1
centrosomal Nek2-associated protein 1
CEP250
Centrosomal protein 2
centrosome-associated protein CEP250

Language	Label	Description	Also known as
English	Centrosomal protein 250	mammalian protein found in Homo sapiens	250 kDa centrosomal protein C-Nap1 centrosomal Nek2-associated protein 1 CEP250 Centrosomal protein 2 centrosome-associated protein CEP250

Statements

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

13 November 2019

protein domain specific binding

1 reference

8 April 2019

Centlein mediates an interaction between C-Nap1 and Cep68 to maintain centrosome cohesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BV73

determination method

IPI

protein C-terminus binding

1 reference

8 April 2019

A novel function of CEP135 as a platform protein of C-NAP1 for its centriolar localization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BV73

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BV73

8 April 2019

SIK2 is a centrosome kinase required for bipolar mitotic spindle formation that provides a potential target for therapy in ovarian cancer

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BV73

8 April 2019

Conductin/axin2 and Wnt signalling regulates centrosome cohesion

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BV73

determination method

IPI

protein kinase binding

1 reference

8 April 2019

C-Nap1, a novel centrosomal coiled-coil protein and candidate substrate of the cell cycle-regulated protein kinase Nek2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BV73

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BV73

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BV73

3 references

8 April 2019

Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BV73

8 April 2019

C-Nap1, a novel centrosomal coiled-coil protein and candidate substrate of the cell cycle-regulated protein kinase Nek2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BV73

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BV73

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BV73

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BV73

determination method

IEA

microtubule organizing center

1 reference

31 October 2017

C-Nap1, a novel centrosomal coiled-coil protein and candidate substrate of the cell cycle-regulated protein kinase Nek2

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BV73&geneProductId=UniProtKB:Q9BV73

determination method

NAS

perinuclear region of cytoplasm

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BV73

7 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BV73

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BV73

8 April 2019

MDM1 is a microtubule-binding protein that negatively regulates centriole duplication

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BV73

8 April 2019

The centrosomal protein C-Nap1 is required for cell cycle-regulated centrosome cohesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BV73

8 April 2019

A Conserved Role for Girdin in Basal Body Positioning and Ciliogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BV73

8 April 2019

A novel function of CEP135 as a platform protein of C-NAP1 for its centriolar localization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BV73

8 April 2019

The CP110-interacting proteins Talpid3 and Cep290 play overlapping and distinct roles in cilia assembly

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BV73

determination method

IDA

extracellular exosome

1 reference

31 October 2017

Large-scale proteomics and phosphoproteomics of urinary exosomes

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BV73&geneProductId=UniProtKB:Q9BV73

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BV73

determination method

IEA

protein-containing complex

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BV73

determination method

IMP

extracellular exosome

1 reference

8 April 2019

Large-scale proteomics and phosphoproteomics of urinary exosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BV73

determination method

HDA

biological process

protein localization to organelle

1 reference

8 April 2019

Centlein mediates an interaction between C-Nap1 and Cep68 to maintain centrosome cohesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BV73

determination method

IMP

regulation of centriole-centriole cohesion

1 reference

8 April 2019

C-Nap1, a novel centrosomal coiled-coil protein and candidate substrate of the cell cycle-regulated protein kinase Nek2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BV73

determination method

IDA

centriole-centriole cohesion

4 references

8 April 2019

The centrosomal protein C-Nap1 is required for cell cycle-regulated centrosome cohesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BV73

8 April 2019

Centlein mediates an interaction between C-Nap1 and Cep68 to maintain centrosome cohesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BV73

8 April 2019

A novel function of CEP135 as a platform protein of C-NAP1 for its centriolar localization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BV73

8 April 2019

3D-structured illumination microscopy provides novel insight into architecture of human centrosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BV73

determination method

IMP

G2/M transition of mitotic cell cycle

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BV73

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BV73

1 reference

8 April 2019

The mechanism regulating the dissociation of the centrosomal protein C-Nap1 from mitotic spindle poles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BV73

determination method

IDA

ciliary basal body-plasma membrane docking

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BV73

determination method

TAS

positive regulation of protein localization to centrosome

1 reference

8 April 2019

A Conserved Role for Girdin in Basal Body Positioning and Ciliogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BV73

determination method

IMP

non-motile cilium assembly

1 reference

8 April 2019

Primary ciliogenesis requires the distal appendage component Cep123.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BV73

determination method

IMP

regulation of G2/M transition of mitotic cell cycle

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BV73

determination method

TAS

physically interacts with

1 reference

https://thebiogrid.org/news/227

retrieved

19 April 2020

stated in

BioGRID

A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

Centrosomal protein 250 (Q21115402)

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Centrosomal protein 250 (Q21115402)

Statements

Identifiers

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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