BTB domain and CNC homolog 1 (Q21115419)

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mammalian protein found in Homo sapiens

BTB and CNC homolog 1
transcription regulator protein BACH1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
basic region leucine zipper transcriptional regulator BACH1
HA2303

Language	Label	Description	Also known as
English	BTB domain and CNC homolog 1	mammalian protein found in Homo sapiens	BTB and CNC homolog 1 transcription regulator protein BACH1 BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 basic region leucine zipper transcriptional regulator BACH1 HA2303

Statements

1 reference

13 November 2019

UniProt protein ID

SKP1/BTB/POZ domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O14867

Transcription factor, Skn-1-like, DNA-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O14867

Basic-leucine zipper domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Basic leucine zipper domain, Maf-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

BTB/POZ domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

determination method or standard

DNA-binding transcription factor activity

determination method or standard

ubiquitin-protein transferase activity

determination method or standard

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14867&geneProductId=UniProtKB:O14867

determination method or standard

DNA-binding transcription repressor activity, RNA polymerase II-specific

determination method or standard

1 reference

26 September 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14867&geneProductId=UniProtKB:O14867

determination method or standard

DNA-binding transcription repressor activity, RNA polymerase II-specific

determination method or standard

protein binding

determination method or standard

determination method or standard

1 reference

8 April 2019

The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14867

determination method or standard

RNA polymerase II cis-regulatory region sequence-specific DNA binding

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14867

determination method or standard

DNA-binding transcription factor activity, RNA polymerase II-specific

determination method or standard

3 references

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14867

determination method or standard

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14867

determination method or standard

8 April 2019

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14867

determination method or standard

DNA-binding transcription repressor activity, RNA polymerase II-specific

determination method or standard

4 references

8 April 2019

The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14867

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14867

determination method or standard

8 April 2019

Parallel SCF adaptor capture proteomics reveals a role for SCFFBXL17 in NRF2 activation via BACH1 repressor turnover.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14867

determination method or standard

8 April 2019

Bach1 functions as a hypoxia-inducible repressor for the heme oxygenase-1 gene in human cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14867

determination method or standard

determination method or standard

1 reference

26 September 2017

Dynamic proteomics in individual human cells uncovers widespread cell-cycle dependence of nuclear proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14867&geneProductId=UniProtKB:O14867

determination method or standard

determination method or standard

1 reference

26 September 2017

Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14867&geneProductId=UniProtKB:O14867

determination method or standard

Cul3-RING ubiquitin ligase complex

determination method or standard

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14867&geneProductId=UniProtKB:O14867

determination method or standard

determination method or standard

6 references

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14867&geneProductId=UniProtKB:O14867

determination method or standard

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14867&geneProductId=UniProtKB:O14867

determination method or standard

26 September 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14867&geneProductId=UniProtKB:O14867

determination method or standard

26 September 2017

Bach1 functions as a hypoxia-inducible repressor for the heme oxygenase-1 gene in human cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14867&geneProductId=UniProtKB:O14867

determination method or standard

26 September 2017

Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14867&geneProductId=UniProtKB:O14867

determination method or standard

26 September 2017

Dynamic proteomics in individual human cells uncovers widespread cell-cycle dependence of nuclear proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14867&geneProductId=UniProtKB:O14867

determination method or standard

determination method or standard

7 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14867

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14867

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14867

determination method or standard

8 April 2019

Parallel SCF adaptor capture proteomics reveals a role for SCFFBXL17 in NRF2 activation via BACH1 repressor turnover.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14867

determination method or standard

8 April 2019

Bach1 functions as a hypoxia-inducible repressor for the heme oxygenase-1 gene in human cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14867

determination method or standard

8 April 2019

Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14867

determination method or standard

8 April 2019

Dynamic proteomics in individual human cells uncovers widespread cell-cycle dependence of nuclear proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14867

determination method or standard

determination method or standard

1 reference

8 April 2019

Dynamic proteomics in individual human cells uncovers widespread cell-cycle dependence of nuclear proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14867

determination method or standard

determination method or standard

1 reference

8 April 2019

Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14867

determination method or standard

biological process

regulation of transcription, DNA-templated

determination method or standard

negative regulation of transcription by RNA polymerase II

determination method or standard

regulation of transcription involved in G1/S transition of mitotic cell cycle

determination method or standard

1 reference

8 April 2019

The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14867

determination method or standard

transcription, DNA-templated

determination method or standard

1 reference

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14867&geneProductId=UniProtKB:O14867

determination method or standard

regulation of transcription from RNA polymerase II promoter in response to hypoxia

determination method or standard

1 reference

8 April 2019

Bach1 functions as a hypoxia-inducible repressor for the heme oxygenase-1 gene in human cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14867

determination method or standard

determination method or standard

1 reference

8 April 2019

BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14867

determination method or standard

positive regulation of transcription by RNA polymerase II

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14867

determination method or standard

regulation of transcription involved in G2/M transition of mitotic cell cycle

determination method or standard

1 reference

8 April 2019

The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14867

determination method or standard

protein ubiquitination

determination method or standard

1 reference

26 September 2017

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14867&geneProductId=UniProtKB:O14867

determination method or standard

transcription by RNA polymerase II

determination method or standard

1 reference

26 September 2017

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14867&geneProductId=UniProtKB:O14867

determination method or standard

negative regulation of transcription by RNA polymerase II

determination method or standard

3 references

8 April 2019

The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14867

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14867

determination method or standard

8 April 2019

Parallel SCF adaptor capture proteomics reveals a role for SCFFBXL17 in NRF2 activation via BACH1 repressor turnover.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14867

determination method or standard

Basic leucine zipper domain, Maf-type

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O14867

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O14867

Basic-leucine zipper domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O14867

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000286800

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000286800

ENSP00000382805

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000382805

ENSP00000392202

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000392202

ENSP00000400576

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000400576

ENSP00000408605

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000408605

ENSP00000416569

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000416569

ENSP00000447332

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000447332

ENSP00000448663

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000448663

ENSP00000448982

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000448982

ENSP00000449316

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000449316

ENSP00000449383

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000449383

ENSP00000470673

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000470673

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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