Autophagy related 14 (Q21115454)

From Wikidata

Jump to navigation Jump to search

mammalian protein found in Homo sapiens

Beclin 1-Interacting protein
Atg14L
autophagy-related protein 14-like protein
ATG14 autophagy related 14 homolog
ATG14
beclin 1-associated autophagy-related key regulator

Language	Label	Description	Also known as
English	Autophagy related 14	mammalian protein found in Homo sapiens	Beclin 1-Interacting protein Atg14L autophagy-related protein 14-like protein ATG14 autophagy related 14 homolog ATG14 beclin 1-associated autophagy-related key regulator

Statements

1 reference

13 November 2019

UniProt protein ID

UV radiation resistance protein/autophagy-related protein 14

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q6ZNE5

Autophagy-related Phagophore-formation Transporter

1 reference

Transporter Classification Database ID

2 October 2019

based on heuristic

hierarchical database ID heuristic

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

protein binding

determination method

17 references

8 April 2019

Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZNE5

determination method

8 April 2019

Beclin 2 functions in autophagy, degradation of G protein-coupled receptors, and metabolism

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZNE5

determination method

8 April 2019

TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZNE5

determination method

8 April 2019

Network organization of the human autophagy system

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZNE5

determination method

8 April 2019

NRBF2 regulates macroautophagy as a component of Vps34 Complex I

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZNE5

determination method

8 April 2019

The RUN domain of rubicon is important for hVps34 binding, lipid kinase inhibition, and autophagy suppression

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZNE5

determination method

8 April 2019

A kinase-independent role for EGF receptor in autophagy initiation

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZNE5

determination method

8 April 2019

Architecture and dynamics of the autophagic phosphatidylinositol 3-kinase complex

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZNE5

determination method

8 April 2019

EGFR-mediated Beclin 1 phosphorylation in autophagy suppression, tumor progression, and tumor chemoresistance

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZNE5

determination method

8 April 2019

A human interactome in three quantitative dimensions organized by stoichiometries and abundances

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZNE5

determination method

8 April 2019

Beclin 2 functions in autophagy, degradation of G protein-coupled receptors, and metabolism

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZNE5

determination method

8 April 2019

Akt-mediated regulation of autophagy and tumorigenesis through Beclin 1 phosphorylation

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZNE5

determination method

8 April 2019

Receptor signaling lymphocyte-activation molecule family 1 (Slamf1) regulates membrane fusion and NADPH oxidase 2 (NOX2) activity by recruiting a Beclin-1/Vps34/ultraviolet radiation resistance-associated gene (UVRAG) complex

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZNE5

determination method

8 April 2019

Identification of Barkor as a mammalian autophagy-specific factor for Beclin 1 and class III phosphatidylinositol 3-kinase

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZNE5

determination method

8 April 2019

Inhibition of autophagy by TAB2 and TAB3

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZNE5

determination method

8 April 2019

Differential regulation of distinct Vps34 complexes by AMPK in nutrient stress and autophagy

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZNE5

determination method

8 April 2019

ATG14 promotes membrane tethering and fusion of autophagosomes to endolysosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZNE5

determination method

determination method

1 reference

8 April 2019

IRGM Governs the Core Autophagy Machinery to Conduct Antimicrobial Defense

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZNE5

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZNE5

determination method

phagophore assembly site membrane

determination method

3 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6ZNE5&geneProductId=UniProtKB:Q6ZNE5

determination method

21 June 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6ZNE5&geneProductId=UniProtKB:Q6ZNE5

determination method

21 June 2018

Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6ZNE5&geneProductId=UniProtKB:Q6ZNE5

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZNE5

determination method

extrinsic component of omegasome membrane

determination method

1 reference

21 June 2018

Autophagosome targeting and membrane curvature sensing by Barkor/Atg14(L).

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6ZNE5&geneProductId=UniProtKB:Q6ZNE5

determination method

extrinsic component of phagophore assembly site membrane

determination method

1 reference

21 June 2018

Autophagosome targeting and membrane curvature sensing by Barkor/Atg14(L).

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6ZNE5&geneProductId=UniProtKB:Q6ZNE5

determination method

autophagosome membrane

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZNE5

determination method

endoplasmic reticulum

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZNE5

determination method

cytoplasmic vesicle

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZNE5

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZNE5

determination method

determination method

1 reference

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6ZNE5&geneProductId=UniProtKB:Q6ZNE5

determination method

phosphatidylinositol 3-kinase complex, class III

determination method

1 reference

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6ZNE5&geneProductId=UniProtKB:Q6ZNE5

determination method

mitochondria-associated endoplasmic reticulum membrane

determination method

1 reference

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6ZNE5&geneProductId=UniProtKB:Q6ZNE5

determination method

phagocytic vesicle

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZNE5

determination method

determination method

3 references

8 April 2019

Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZNE5

determination method

8 April 2019

ATG14 promotes membrane tethering and fusion of autophagosomes to endolysosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZNE5

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZNE5

determination method

phagophore assembly site membrane

determination method

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZNE5

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZNE5

determination method

8 April 2019

Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZNE5

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZNE5

determination method

phosphatidylinositol 3-kinase complex, class III

determination method

3 references

biological process

regulation of protein phosphorylation

determination method

1 reference

8 April 2019

Role of membrane association and Atg14-dependent phosphorylation in beclin-1-mediated autophagy

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZNE5

determination method

endosome to lysosome transport

determination method

1 reference

8 April 2019

Beclin-1-interacting autophagy protein Atg14L targets the SNARE-associated protein Snapin to coordinate endocytic trafficking

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZNE5

determination method

cellular response to starvation

determination method

1 reference

21 June 2018

Role of membrane association and Atg14-dependent phosphorylation in beclin-1-mediated autophagy

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6ZNE5&geneProductId=UniProtKB:Q6ZNE5

determination method

autophagosome assembly

determination method

1 reference

21 June 2018

Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6ZNE5&geneProductId=UniProtKB:Q6ZNE5

determination method

positive regulation of phosphatidylinositol 3-kinase activity

determination method

1 reference

21 June 2018

The RUN domain of rubicon is important for hVps34 binding, lipid kinase inhibition, and autophagy suppression

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6ZNE5&geneProductId=UniProtKB:Q6ZNE5

determination method

regulation of protein complex stability

determination method

1 reference

8 April 2019

Role of membrane association and Atg14-dependent phosphorylation in beclin-1-mediated autophagy

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZNE5

determination method

posttranscriptional regulation of gene expression

determination method

1 reference

8 April 2019

Role of membrane association and Atg14-dependent phosphorylation in beclin-1-mediated autophagy

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZNE5

determination method

autophagosome membrane docking

determination method

1 reference

8 April 2019

ATG14 promotes membrane tethering and fusion of autophagosomes to endolysosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZNE5

determination method

determination method

1 reference

21 June 2018

Role of membrane association and Atg14-dependent phosphorylation in beclin-1-mediated autophagy

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6ZNE5&geneProductId=UniProtKB:Q6ZNE5

determination method

response to mitochondrial depolarisation

determination method

1 reference

8 April 2019

Role of membrane association and Atg14-dependent phosphorylation in beclin-1-mediated autophagy

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZNE5

determination method

negative regulation of protein phosphorylation

determination method

1 reference

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6ZNE5&geneProductId=UniProtKB:Q6ZNE5

determination method

positive regulation of protein phosphorylation

determination method

1 reference

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6ZNE5&geneProductId=UniProtKB:Q6ZNE5

determination method

cellular response to glucose starvation

determination method

1 reference

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6ZNE5&geneProductId=UniProtKB:Q6ZNE5

determination method

regulation of triglyceride metabolic process

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZNE5

determination method

positive regulation of phosphatidylinositol 3-kinase activity

determination method

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000247178

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000247178

Transporter Classification Database ID

2 references

Transporter Classification database

13 March 2020

Transporter Classification database

29 April 2020

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q21115454&oldid=2022962108"