S100 calcium binding protein A6 (Q21115897)

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mammalian protein found in Homo sapiens

protein S100-A6
S100 calcium-binding protein A6
PRA
calcyclin
S100A6
growth factor-inducible protein 2A9
MLN 4
prolactin receptor-associated protein

Language	Label	Description	Also known as
English	S100 calcium binding protein A6	mammalian protein found in Homo sapiens	protein S100-A6 S100 calcium-binding protein A6 PRA calcyclin S100A6 growth factor-inducible protein 2A9 MLN 4 prolactin receptor-associated protein

Statements

1 reference

13 November 2019

UniProt protein ID

Protein S100-A6

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P06703

EF-hand domain pair

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P06703

EF-hand domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

S100/CaBP-9k-type, calcium binding, subdomain, protein family

1 reference

based on heuristic

inferred from protein domain or family

EF-Hand 1, calcium-binding site, protein family

1 reference

based on heuristic

inferred from protein domain or family

S100/Calbindin-D9k, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

calcium ion binding

determination method

4 references

8 April 2019

Calcyclin (S100A6) regulates pulmonary fibroblast proliferation, morphology, and cytoskeletal organization in vitro

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06703

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06703

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06703

determination method

8 April 2019

Crystal structures of S100A6 in the Ca(2+)-free and Ca(2+)-bound states: the calcium sensor mechanism of S100 proteins revealed at atomic resolution

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06703

determination method

S100 protein binding

determination method

1 reference

8 April 2019

S100A6 and S100A11 are specific targets of the calcium- and zinc-binding S100B protein in vivo

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06703

determination method

protein homodimerization activity

determination method

ion transmembrane transporter activity

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06703

determination method

zinc ion binding

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06703

determination method

metal ion binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06703

determination method

calcium-dependent protein binding

determination method

1 reference

8 April 2019

S100A6 and S100A11 are specific targets of the calcium- and zinc-binding S100B protein in vivo

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06703

determination method

protein binding

determination method

8 references

8 April 2019

S100A6 binds to annexin 2 in pancreatic cancer cells and promotes pancreatic cancer cell motility

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06703

determination method

8 April 2019

Calcyclin (S100A6) regulates pulmonary fibroblast proliferation, morphology, and cytoskeletal organization in vitro

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06703

determination method

8 April 2019

S100 proteins regulate the interaction of Hsp90 with Cyclophilin 40 and FKBP52 through their tetratricopeptide repeats

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06703

determination method

8 April 2019

Regulation of nuclear localization signal-importin α interaction by Ca2+/S100A6

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06703

determination method

8 April 2019

LuTHy: a double-readout bioluminescence-based two-hybrid technology for quantitative mapping of protein-protein interactions in mammalian cells

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06703

determination method

8 April 2019

S100A6 and S100A11 are specific targets of the calcium- and zinc-binding S100B protein in vivo

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06703

determination method

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06703

determination method

8 April 2019

S100 proteins interact with the N-terminal domain of MDM2

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06703

determination method

tropomyosin binding

determination method

1 reference

8 April 2019

S100A6 binds to annexin 2 in pancreatic cancer cells and promotes pancreatic cancer cell motility

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06703

determination method

determination method

4 references

8 April 2019

Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06703

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06703

determination method

8 April 2019

S100A6 and S100A11 are specific targets of the calcium- and zinc-binding S100B protein in vivo

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06703

determination method

8 April 2019

Calcium- and cell cycle-dependent association of annexin 11 with the nuclear envelope

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06703

determination method

nuclear envelope

determination method

4 references

8 April 2019

Calcyclin (S100A6) regulates pulmonary fibroblast proliferation, morphology, and cytoskeletal organization in vitro

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06703

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06703

determination method

8 April 2019

Calcium- and cell cycle-dependent association of annexin 11 with the nuclear envelope

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06703

determination method

8 April 2019

Dissecting the cellular functions of annexin XI using recombinant human annexin XI-specific autoantibodies cloned by phage display

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06703

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06703

determination method

determination method

1 reference

8 April 2019

S100A6 and S100A11 are specific targets of the calcium- and zinc-binding S100B protein in vivo

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06703

determination method

extrinsic component of cytoplasmic side of plasma membrane

determination method

1 reference

8 April 2019

S100A6 binds to annexin 2 in pancreatic cancer cells and promotes pancreatic cancer cell motility

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06703

determination method

plasma membrane

determination method

1 reference

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06703&geneProductId=UniProtKB:P06703

determination method

perinuclear region of cytoplasm

determination method

1 reference

8 April 2019

S100A13 and S100A6 exhibit distinct translocation pathways in endothelial cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06703

determination method

extracellular exosome

determination method

3 references

17 October 2017

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06703&geneProductId=UniProtKB:P06703

determination method

17 October 2017

Large-scale proteomics and phosphoproteomics of urinary exosomes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06703&geneProductId=UniProtKB:P06703

determination method

17 October 2017

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06703&geneProductId=UniProtKB:P06703

determination method

extracellular region

determination method

1 reference

17 October 2017

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06703&geneProductId=UniProtKB:P06703

determination method

extracellular region

determination method

1 reference

8 April 2019

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06703

determination method

biological process

determination method

1 reference

8 April 2019

S100A6 overexpression within astrocytes associated with impaired axons from both ALS mouse model and human patients

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06703

determination method

positive regulation of fibroblast proliferation

determination method

1 reference

8 April 2019

Calcyclin (S100A6) regulates pulmonary fibroblast proliferation, morphology, and cytoskeletal organization in vitro

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06703

determination method

ion transmembrane transport

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06703

determination method

signal transduction

determination method

1 reference

8 April 2019

Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06703

determination method

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000357708

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000357708

ENSP00000357709

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000357709

ENSP00000473589

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000473589

ENSP00000473547

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000473547

PDB structure ID

1 reference

UniProt protein ID

21 March 2016

language of work or name

1 reference

UniProt protein ID

21 March 2016

language of work or name

1 reference

UniProt protein ID

21 March 2016

language of work or name

1 reference

UniProt protein ID

21 March 2016

language of work or name

1 reference

UniProt protein ID

21 March 2016

language of work or name

1 reference

UniProt protein ID

21 March 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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