Dynamin 2 (Q21116465)

P-loop containing nucleoside triphosphate hydrolase

1 reference

Dynamin-2

1 reference

auxiliary protein involved in transmembrane transport

1 reference

Transporter Classification Database ID

8.A.34.1.4

retrieved

2 October 2019

hierarchical database ID heuristic

Membrane contact site

1 reference

Transporter Classification Database ID

1.R.1.1.1

retrieved

2 October 2019

hierarchical database ID heuristic

pleckstrin homology domain, protein family

1 reference

Dynamin GTPase effector, protein family

1 reference

GTPase effector domain, protein family

1 reference

Dynamin, GTPase domain, protein family

1 reference

dynamin

1 reference

Dynamin central domain, protein family

1 reference

Dynamin, GTPase region, conserved site, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

image

DNM2 protein.png
1,920 × 975; 804 KB

0 references

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

nitric-oxide synthase binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

phosphatidylinositol 3-kinase regulatory subunit binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

D2 dopamine receptor binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

3 references

8 April 2019

Isolation of an ubiquitously expressed cDNA encoding human dynamin II, a member of the large GTP-binding protein family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

19 references

8 April 2019

Identification of novel NPRAP/δ-catenin-interacting proteins and the direct association of NPRAP with dynamin 2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

8 April 2019

Mutations in amphiphysin 2 (BIN1) disrupt interaction with dynamin 2 and cause autosomal recessive centronuclear myopathy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

8 April 2019

SNX9 regulates dynamin assembly and is required for efficient clathrin-mediated endocytosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

8 April 2019

Dynamin isoform-specific interaction with the shank/ProSAP scaffolding proteins of the postsynaptic density and actin cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

8 April 2019

A Dyn2-CIN85 complex mediates degradative traffic of the EGFR by regulation of late endosomal budding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

8 April 2019

A directed protein interaction network for investigating intracellular signal transduction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

8 April 2019

Myosin 1E interacts with synaptojanin-1 and dynamin and is involved in endocytosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

8 April 2019

Molecular and structural characterization of the SH3 domain of AHI-1 in regulation of cellular resistance of BCR-ABL(+) chronic myeloid leukemia cells to tyrosine kinase inhibitors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

8 April 2019

TTP specifically regulates the internalization of the transferrin receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

8 April 2019

Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

8 April 2019

Targeting AMAP1 and cortactin binding bearing an atypical src homology 3/proline interface for prevention of breast cancer invasion and metastasis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

8 April 2019

Complexes of syndapin II with dynamin II promote vesicle formation at the trans-Golgi network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

8 April 2019

Membrane trafficking. Nucleoside diphosphate kinases fuel dynamin superfamily proteins with GTP for membrane remodeling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

8 April 2019

Toward an understanding of the protein interaction network of the human liver

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

8 April 2019

Two mechanistically distinct forms of endocytosis in adrenal chromaffin cells: Differential effects of SH3 domains and amphiphysin antagonism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

8 April 2019

Dynamin 2 is required for the enhancement of HIV-1 infectivity by Nef.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

8 April 2019

Pooled-matrix protein interaction screens using Barcode Fusion Genetics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

8 April 2019

Charting the molecular network of the drug target Bcr-Abl

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

8 April 2019

SNX9 regulates tubular invagination of the plasma membrane through interaction with actin cytoskeleton and dynamin 2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

1 reference

8 April 2019

Dynamin isoform-specific interaction with the shank/ProSAP scaffolding proteins of the postsynaptic density and actin cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

protein kinase binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

8 April 2019

Dynamin isoform-specific interaction with the shank/ProSAP scaffolding proteins of the postsynaptic density and actin cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

endocytic vesicle membrane

cell component

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

8 April 2019

SNX9 regulates tubular invagination of the plasma membrane through interaction with actin cytoskeleton and dynamin 2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50570&geneProductId=UniProtKB:P50570

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50570&geneProductId=UniProtKB:P50570

1 reference

17 October 2017

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50570&geneProductId=UniProtKB:P50570

photoreceptor inner segment

IDA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

clathrin-coated endocytic vesicle

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50570&geneProductId=UniProtKB:P50570

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

perinuclear region of cytoplasm

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

3 references

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50570&geneProductId=UniProtKB:P50570

phagocytic vesicle membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50570&geneProductId=UniProtKB:P50570

mitochondrial membranes

1 reference

17 October 2017

3 references

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

1 reference

8 April 2019

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

protein-containing complex

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

postsynaptic membrane

3 references

8 April 2019

8 April 2019

Dynamin isoform-specific interaction with the shank/ProSAP scaffolding proteins of the postsynaptic density and actin cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

postsynaptic endocytic zone membrane

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

glutamatergic synapse

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

postsynaptic density, intracellular component

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

negative regulation of membrane tubulation

biological process

1 reference

8 April 2019

SNX9 regulates tubular invagination of the plasma membrane through interaction with actin cytoskeleton and dynamin 2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

G protein-coupled receptor internalization

IDA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

positive regulation of phagocytosis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

regulation of transcription, DNA-templated

1 reference

8 April 2019

Evidence that dynamin-2 functions as a signal-transducing GTPase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

4 references

8 April 2019

Dynamin II is involved in endocytosis but not in the formation of transport vesicles from the trans-Golgi network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

8 April 2019

Dynamin isoform-specific interaction with the shank/ProSAP scaffolding proteins of the postsynaptic density and actin cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

ventricular septum development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

antigen processing and presentation of exogenous peptide antigen via MHC class II

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

Analysis of clathrin-mediated endocytosis of epidermal growth factor receptor by RNA interference

TAS

transferrin transport

1 reference

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

response to light stimulus

IMP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

cellular response to X-ray

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

positive regulation of nitric oxide biosynthetic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

cellular response to dopamine

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

regulation of nitric-oxide synthase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

Analysis of clathrin-mediated endocytosis of epidermal growth factor receptor by RNA interference

TAS

receptor internalization

1 reference

17 October 2017

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50570&geneProductId=UniProtKB:P50570

regulation of Rac protein signal transduction

IMP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

negative regulation of transforming growth factor beta receptor signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

coronary vasculature development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

positive regulation of transcription, DNA-templated

1 reference

8 April 2019

Evidence that dynamin-2 functions as a signal-transducing GTPase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

positive regulation of P-type sodium:potassium-exchanging transporter activity

NAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

positive regulation of endocytosis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

positive regulation of substrate adhesion-dependent cell spreading

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

regulation of Golgi organization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

G2/M transition of mitotic cell cycle

1 reference

8 April 2019

Isolation of an ubiquitously expressed cDNA encoding human dynamin II, a member of the large GTP-binding protein family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

positive regulation of apoptotic process

1 reference

8 April 2019

Evidence that dynamin-2 functions as a signal-transducing GTPase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

synaptic vesicle transport

NAS

1 reference

8 April 2019

Dynamin isoform-specific interaction with the shank/ProSAP scaffolding proteins of the postsynaptic density and actin cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

cellular response to nitric oxide

NAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

positive regulation of lamellipodium assembly

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

Golgi to plasma membrane transport

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

cellular response to carbon monoxide

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

1 reference

8 April 2019

Evidence that dynamin-2 functions as a signal-transducing GTPase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50570&geneProductId=UniProtKB:P50570

mitochondrial fission

1 reference

17 October 2017

dynamin family protein polymerization involved in mitochondrial fission

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50570&geneProductId=UniProtKB:P50570

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

membrane organization

1 reference

8 April 2019

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50570&geneProductId=UniProtKB:P50570

negative regulation of non-motile cilium assembly

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

synaptic vesicle budding from presynaptic endocytic zone membrane

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

synaptic vesicle endocytosis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

regulation of synapse structure or activity

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

postsynaptic neurotransmitter receptor internalization

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

positive regulation of clathrin-dependent endocytosis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50570

has part(s)

GTPase effector domain

1 reference

pleckstrin homology domain

1 reference

Dynamin, GTPase domain

1 reference

Dynamin GTPase effector

1 reference

Dynamin central domain

1 reference

Dynamin, GTPase region, conserved site

1 reference

Dynamin-type guanine nucleotide-binding (G) domain

1 reference

Transporter Classification Database ID

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

language of work or name

English

1.R.1.1.1

1 reference