ETS proto-oncogene 1, transcription factor (Q21116585)

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mammalian protein found in Homo sapiens
  • protein C-ets-1
  • p54
  • v-ets avian erythroblastosis virus E2 oncogene homolog 1
  • Avian erythroblastosis virus E26 (v-ets) oncogene homolog-1
  • v-ets avian erythroblastosis virus E26 oncogene homolog 1
  • ETS1
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Language Label Description Also known as
English
ETS proto-oncogene 1, transcription factor
mammalian protein found in Homo sapiens
  • protein C-ets-1
  • p54
  • v-ets avian erythroblastosis virus E2 oncogene homolog 1
  • Avian erythroblastosis virus E26 (v-ets) oncogene homolog-1
  • v-ets avian erythroblastosis virus E26 oncogene homolog 1
  • ETS1

Statements

molecular function
protein binding
determination method or standard
IPI
12 references
retrieved
8 April 2019
stated in
EAP1/Daxx interacts with ETS1 and represses transcriptional activation of ETS1 target genes
GOA
curator
UniProt
UniProt protein ID
P14921
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14921
determination method or standard
IPI
retrieved
8 April 2019
stated in
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14921
determination method or standard
IPI
retrieved
8 April 2019
stated in
ETS-dependent p16INK4a and p21waf1/cip1 gene expression upon endothelin-1 stimulation in malignant versus and non-malignant proximal tubule cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14921
determination method or standard
IPI
retrieved
8 April 2019
stated in
Mechanistic rationale for inhibition of poly(ADP-ribose) polymerase in ETS gene fusion-positive prostate cancer
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14921
determination method or standard
IPI
retrieved
8 April 2019
stated in
Differential genomic targeting of the transcription factor TAL1 in alternate haematopoietic lineages
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14921
determination method or standard
IPI
retrieved
8 April 2019
stated in
EAP1/Daxx interacts with ETS1 and represses transcriptional activation of ETS1 target genes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14921
determination method or standard
IPI
retrieved
8 April 2019
stated in
Cooperative interaction between ETS1 and GFI1 transcription factors in the repression of Bax gene expression
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14921
determination method or standard
IPI
retrieved
8 April 2019
stated in
A comprehensive resource of interacting protein regions for refining human transcription factor networks
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14921
determination method or standard
IPI
retrieved
8 April 2019
stated in
SP100 expression modulates ETS1 transcriptional activity and inhibits cell invasion
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14921
determination method or standard
IPI
retrieved
8 April 2019
stated in
Toward an understanding of the protein interaction network of the human liver
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14921
determination method or standard
IPI
retrieved
8 April 2019
stated in
Physical and functional interactions between hematopoietic cell-specific ETS transcription factors and homeodomain proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14921
determination method or standard
IPI
retrieved
8 April 2019
stated in
Sp100 interacts with ETS-1 and stimulates its transcriptional activity
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14921
determination method or standard
IPI
DNA-binding transcription factor activity, RNA polymerase II-specific
determination method or standard
IBA
IDA
ISA
ISM
NAS
5 references
retrieved
8 April 2019
stated in
A census of human transcription factors: function, expression and evolution
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14921
determination method or standard
NAS
retrieved
8 April 2019
stated in
A census of human transcription factors: function, expression and evolution
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14921
determination method or standard
ISM
retrieved
8 April 2019
stated in
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14921
determination method or standard
ISA
retrieved
8 April 2019
stated in
Constitutive activation of the ETS-1-miR-222 circuitry in metastatic melanoma
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14921
determination method or standard
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14921
determination method or standard
IBA
cell component
nucleus
determination method or standard
IDA
IEA
IMP
7 references
retrieved
24 April 2018
stated in
EAP1/Daxx interacts with ETS1 and represses transcriptional activation of ETS1 target genes
GOA
curator
UniProt
UniProt protein ID
P14921
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P14921&geneProductId=UniProtKB:P14921
determination method or standard
IMP
retrieved
24 April 2018
stated in
A variant form of ETS1 induces apoptosis in human colon cancer cells
GOA
curator
UniProt
UniProt protein ID
P14921
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P14921&geneProductId=UniProtKB:P14921
determination method or standard
IMP
retrieved
24 April 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P14921
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P14921&geneProductId=UniProtKB:P14921
determination method or standard
IEA
retrieved
24 April 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P14921&geneProductId=UniProtKB:P14921
determination method or standard
IEA
retrieved
24 April 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P14921&geneProductId=UniProtKB:P14921
determination method or standard
IEA
retrieved
24 April 2018
stated in
SP100 expression modulates ETS1 transcriptional activity and inhibits cell invasion
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P14921&geneProductId=UniProtKB:P14921
determination method or standard
IDA
retrieved
24 April 2018
stated in
Sp100 interacts with ETS-1 and stimulates its transcriptional activity
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P14921&geneProductId=UniProtKB:P14921
determination method or standard
IDA
biological process

Identifiers

MeSH descriptor ID
D050784
subject named as
Proto-Oncogene Protein c-ets-1
0 references
PDB structure ID
 
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