Atlastin GTPase 1 (Q21116759)

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mammalian protein found in Homo sapiens

ATL1
spastic paraplegia 3 protein A
guanylate-binding protein 3
GTP-binding protein 3
atlastin-1
guanine nucleotide-binding protein 3
hGBP3
brain-specific GTP-binding protein
GBP-3

Language	Label	Description	Also known as
English	Atlastin GTPase 1	mammalian protein found in Homo sapiens	ATL1 spastic paraplegia 3 protein A guanylate-binding protein 3 GTP-binding protein 3 atlastin-1 guanine nucleotide-binding protein 3 hGBP3 brain-specific GTP-binding protein GBP-3

Statements

1 reference

13 November 2019

UniProt protein ID

Guanylate-binding protein, C-terminal domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8WXF7

P-loop containing nucleoside triphosphate hydrolase

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8WXF7

membrane fusion pore

1 reference

Transporter Classification Database ID

2 October 2019

based on heuristic

hierarchical database ID heuristic

Guanylate-binding protein, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

GB1/RHD3-type guanine nucleotide-binding (G) domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

nucleotide binding

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF7

determination method

determination method

4 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF7

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF7

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF7

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF7

determination method

protein binding

determination method

6 references

9 May 2019

Interaction of two hereditary spastic paraplegia gene products, spastin and atlastin, suggests a common pathway for axonal maintenance

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF7

determination method

9 May 2019

Hereditary spastic paraplegia proteins REEP1, spastin, and atlastin-1 coordinate microtubule interactions with the tubular ER network

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF7

determination method

9 May 2019

A class of dynamin-like GTPases involved in the generation of the tubular ER network

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF7

determination method

9 May 2019

Mutation in CPT1C Associated With Pure Autosomal Dominant Spastic Paraplegia

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF7

determination method

9 May 2019

Protrudin binds atlastins and endoplasmic reticulum-shaping proteins and regulates network formation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF7

determination method

9 May 2019

A class of dynamin-like GTPases involved in the generation of the tubular ER network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF7

determination method

hydrolase activity

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF7

determination method

GTPase activity

determination method

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF7

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF7

determination method

8 April 2019

Cellular Localization, Oligomerization, and Membrane Association of the Hereditary Spastic Paraplegia 3A (SPG3A) Protein Atlastin

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF7

determination method

identical protein binding

determination method

4 references

9 May 2019

Structural basis for the nucleotide-dependent dimerization of the large G protein atlastin-1/SPG3A

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF7

determination method

9 May 2019

Structures of the atlastin GTPase provide insight into homotypic fusion of endoplasmic reticulum membranes

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF7

determination method

9 May 2019

Structural basis for conformational switching and GTP loading of the large G protein atlastin

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF7

determination method

9 May 2019

Cellular Localization, Oligomerization, and Membrane Association of the Hereditary Spastic Paraplegia 3A (SPG3A) Protein Atlastin

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF7

determination method

GTPase activity

determination method

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF7

determination method

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF7

determination method

9 May 2019

Cellular Localization, Oligomerization, and Membrane Association of the Hereditary Spastic Paraplegia 3A (SPG3A) Protein Atlastin

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF7

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF7

determination method

determination method

5 references

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF7

determination method

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF7

determination method

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF7

determination method

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF7

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF7

determination method

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF7

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF7

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF7

determination method

Golgi apparatus

determination method

cell projection

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF7

determination method

endoplasmic reticulum membrane

determination method

endoplasmic reticulum

determination method

3 references

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF7

determination method

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF7

determination method

9 May 2019

A class of dynamin-like GTPases involved in the generation of the tubular ER network

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF7

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF7

determination method

endoplasmic reticulum tubular network membrane

determination method

1 reference

9 May 2019

Cooperation of the ER-shaping proteins atlastin, lunapark, and reticulons to generate a tubular membrane network

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF7

determination method

biological process

protein homooligomerization

determination method

1 reference

8 April 2019

Cellular Localization, Oligomerization, and Membrane Association of the Hereditary Spastic Paraplegia 3A (SPG3A) Protein Atlastin

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF7

determination method

endoplasmic reticulum organization

determination method

1 reference

8 April 2019

A class of dynamin-like GTPases involved in the generation of the tubular ER network

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF7

determination method

endoplasmic reticulum tubular network membrane organization

determination method

1 reference

9 May 2019

Cooperation of the ER-shaping proteins atlastin, lunapark, and reticulons to generate a tubular membrane network

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF7

determination method

GB1/RHD3-type guanine nucleotide-binding (G) domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8WXF7

Guanylate-binding protein, N-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8WXF7

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000351155

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000351155

ENSP00000413675

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000413675

ENSP00000450897

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000450897

ENSP00000450989

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000450989

ENSP00000451015

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000451015

ENSP00000451100

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000451100

ENSP00000452074

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000452074

ENSP00000452506

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000452506

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Transporter Classification Database ID

2 references

Transporter Classification database

13 March 2020

Transporter Classification database

29 April 2020

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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