24-hydroxycholesterol 7alpha-hydroxylase activity (Q21117316)

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Catalysis of the reaction: (24R)-cholest-5-ene-3beta,24-diol + H(+) + NADPH + O(2) = (24R)-7alpha,24-dihydroxycholesterol + H(2)O + NADP(+).
  • (24R)-cholest-5-ene-3beta,24-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) activity
  • 24-hydroxycholesterol 7alpha-monooxygenase activity
  • CYP39A1 oxysterol 7alpha-hydroxylase activity
  • GO:0033782
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English
24-hydroxycholesterol 7alpha-hydroxylase activity
Catalysis of the reaction: (24R)-cholest-5-ene-3beta,24-diol + H(+) + NADPH + O(2) = (24R)-7alpha,24-dihydroxycholesterol + H(2)O + NADP(+).
  • (24R)-cholest-5-ene-3beta,24-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) activity
  • 24-hydroxycholesterol 7alpha-monooxygenase activity
  • CYP39A1 oxysterol 7alpha-hydroxylase activity
  • GO:0033782

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