Hydroxysteroid 17-beta dehydrogenase 1 (Q21117480)

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mammalian protein found in Homo sapiens

short chain dehydrogenase/reductase family 28CE, member 1
17-beta-HSD 1
placental 17-beta-hydroxysteroid dehydrogenase
17-beta-hydroxysteroid dehydrogenase type 1
estradiol 17-beta-dehydrogenase 1
20 alpha-hydroxysteroid dehydrogenase
short chain dehydrogenase/reductase family 28C member 1
HSD17B1
20-alpha-HSD
E2DH

Language	Label	Description	Also known as
English	Hydroxysteroid 17-beta dehydrogenase 1	mammalian protein found in Homo sapiens	short chain dehydrogenase/reductase family 28CE, member 1 17-beta-HSD 1 placental 17-beta-hydroxysteroid dehydrogenase 17-beta-hydroxysteroid dehydrogenase type 1 estradiol 17-beta-dehydrogenase 1 20 alpha-hydroxysteroid dehydrogenase short chain dehydrogenase/reductase family 28C member 1 HSD17B1 20-alpha-HSD E2DH

Statements

1 reference

13 November 2019

UniProt protein ID

NAD(P)-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P14061

17beta-dehydrogenase, subgroup

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P14061

Short-chain dehydrogenase/reductase, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

catalytic activity

determination method or standard

1 reference

8 April 2019

Kinetic analysis of enzymic activities: prediction of multiple forms of 17 beta-hydroxysteroid dehydrogenase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14061

determination method or standard

estradiol 17-beta-dehydrogenase activity

determination method or standard

6 references

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P14061&geneProductId=UniProtKB:P14061

determination method or standard

7 November 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P14061&geneProductId=UniProtKB:P14061

determination method or standard

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P14061&geneProductId=UniProtKB:P14061

determination method or standard

7 November 2018

Reaction mechanism of 17-beta-estradiol dehydrogenase determined by equilibrium rate exchange

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P14061&geneProductId=UniProtKB:P14061

determination method or standard

7 November 2018

Dehydroepiandrosterone and dihydrotestosterone recognition by human estrogenic 17beta-hydroxysteroid dehydrogenase. C-18/c-19 steroid discrimination and enzyme-induced strain

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P14061&geneProductId=UniProtKB:P14061

determination method or standard

7 November 2018

Unusual charge stabilization of NADP+ in 17beta-hydroxysteroid dehydrogenase

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P14061&geneProductId=UniProtKB:P14061

determination method or standard

steroid binding

determination method or standard

1 reference

8 April 2019

Reaction mechanism of 17-beta-estradiol dehydrogenase determined by equilibrium rate exchange

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14061

determination method or standard

determination method or standard

1 reference

8 April 2019

Unusual charge stabilization of NADP+ in 17beta-hydroxysteroid dehydrogenase

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14061

determination method or standard

estradiol binding

determination method or standard

1 reference

8 April 2019

Dehydroepiandrosterone and dihydrotestosterone recognition by human estrogenic 17beta-hydroxysteroid dehydrogenase. C-18/c-19 steroid discrimination and enzyme-induced strain

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14061

determination method or standard

estradiol 17-beta-dehydrogenase activity

determination method or standard

5 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14061

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14061

determination method or standard

8 April 2019

Reaction mechanism of 17-beta-estradiol dehydrogenase determined by equilibrium rate exchange

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14061

determination method or standard

8 April 2019

Dehydroepiandrosterone and dihydrotestosterone recognition by human estrogenic 17beta-hydroxysteroid dehydrogenase. C-18/c-19 steroid discrimination and enzyme-induced strain

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14061

determination method or standard

8 April 2019

Unusual charge stabilization of NADP+ in 17beta-hydroxysteroid dehydrogenase

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14061

determination method or standard

determination method or standard

3 references

8 April 2019

Kinetic analysis of enzymic activities: prediction of multiple forms of 17 beta-hydroxysteroid dehydrogenase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14061

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14061

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14061

determination method or standard

biological process

estrogen biosynthetic process

determination method or standard

estrogen metabolic process

determination method or standard

1 reference

8 April 2019

Regulation of the gene for estrogenic 17-ketosteroid reductase lying on chromosome 17cen----q25

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14061

determination method or standard

lipid metabolism

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14061

determination method or standard

Short-chain dehydrogenase/reductase, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P14061

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000466799

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000466799

ENSP00000225929

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000225929

ENSP00000465128

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000465128

PDB structure ID

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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