Neuronal PAS domain protein 4 (Q21118879)

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mammalian protein found in Homo sapiens

NPAS4
neuronal PAS4
neuronal PAS domain-containing protein 4
PAS domain-containing protein 10
HLH-PAS transcription factor NXF
class E basic helix-loop-helix protein 79
bHLHe79

Language	Label	Description	Also known as
English	Neuronal PAS domain protein 4	mammalian protein found in Homo sapiens	NPAS4 neuronal PAS4 neuronal PAS domain-containing protein 4 PAS domain-containing protein 10 HLH-PAS transcription factor NXF class E basic helix-loop-helix protein 79 bHLHe79

Statements

1 reference

13 November 2019

UniProt protein ID

PAS domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8IUM7

Myc-type, basic helix-loop-helix (bHLH) domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

PAS fold-3 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

PAS domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

DNA-binding transcription activator activity, RNA polymerase II-specific

determination method or standard

2 references

10 September 2018

Identification of a novel basic helix-loop-helix-PAS factor, NXF, reveals a Sim2 competitive, positive regulatory role in dendritic-cytoskeleton modulator drebrin gene expression

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IUM7&geneProductId=UniProtKB:Q8IUM7

determination method or standard

8 April 2019

Identification of a novel basic helix-loop-helix-PAS factor, NXF, reveals a Sim2 competitive, positive regulatory role in dendritic-cytoskeleton modulator drebrin gene expression

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IUM7

determination method or standard

protein dimerization activity

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IUM7

determination method or standard

RNA polymerase II cis-regulatory region sequence-specific DNA binding

determination method or standard

2 references

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IUM7

determination method or standard

8 April 2019

Identification of a novel basic helix-loop-helix-PAS factor, NXF, reveals a Sim2 competitive, positive regulatory role in dendritic-cytoskeleton modulator drebrin gene expression

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IUM7

determination method or standard

protein binding

determination method or standard

1 reference

8 April 2019

Human variants in the neuronal basic helix-loop-helix/Per-Arnt-Sim (bHLH/PAS) transcription factor complex NPAS4/ARNT2 disrupt function

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IUM7

determination method or standard

DNA-binding transcription factor activity, RNA polymerase II-specific

determination method or standard

3 references

27 March 2018

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IUM7&geneProductId=UniProtKB:Q8IUM7

determination method or standard

27 March 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IUM7&geneProductId=UniProtKB:Q8IUM7

determination method or standard

27 March 2018

Human variants in the neuronal basic helix-loop-helix/Per-Arnt-Sim (bHLH/PAS) transcription factor complex NPAS4/ARNT2 disrupt function

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IUM7&geneProductId=UniProtKB:Q8IUM7

determination method or standard

DNA-binding transcription factor activity, RNA polymerase II-specific

determination method or standard

4 references

8 April 2019

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IUM7

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IUM7

determination method or standard

8 April 2019

Human variants in the neuronal basic helix-loop-helix/Per-Arnt-Sim (bHLH/PAS) transcription factor complex NPAS4/ARNT2 disrupt function

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IUM7

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IUM7

determination method or standard

determination method or standard

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IUM7

determination method or standard

transcription regulator complex

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IUM7

determination method or standard

determination method or standard

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IUM7

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IUM7

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IUM7

determination method or standard

biological process

positive regulation of transcription, DNA-templated

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IUM7

determination method or standard

regulation of transcription, DNA-templated

determination method or standard

1 reference

27 March 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IUM7&geneProductId=UniProtKB:Q8IUM7

determination method or standard

cellular response to corticosterone stimulus

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IUM7

determination method or standard

positive regulation of transcription by RNA polymerase II

determination method or standard

3 references

27 March 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IUM7&geneProductId=UniProtKB:Q8IUM7

determination method or standard

27 March 2018

Human variants in the neuronal basic helix-loop-helix/Per-Arnt-Sim (bHLH/PAS) transcription factor complex NPAS4/ARNT2 disrupt function

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IUM7&geneProductId=UniProtKB:Q8IUM7

determination method or standard

27 March 2018

Identification of a novel basic helix-loop-helix-PAS factor, NXF, reveals a Sim2 competitive, positive regulatory role in dendritic-cytoskeleton modulator drebrin gene expression

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IUM7&geneProductId=UniProtKB:Q8IUM7

determination method or standard

transcription, DNA-templated

determination method or standard

1 reference

27 March 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IUM7&geneProductId=UniProtKB:Q8IUM7

determination method or standard

transcription by RNA polymerase II

determination method or standard

1 reference

27 March 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IUM7&geneProductId=UniProtKB:Q8IUM7

determination method or standard

nervous system development

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IUM7

determination method or standard

cell differentiation

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IUM7

determination method or standard

regulation of transcription by RNA polymerase II

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IUM7

determination method or standard

positive regulation of transcription by RNA polymerase II

determination method or standard

4 references

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IUM7

determination method or standard

8 April 2019

Human variants in the neuronal basic helix-loop-helix/Per-Arnt-Sim (bHLH/PAS) transcription factor complex NPAS4/ARNT2 disrupt function

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IUM7

determination method or standard

8 April 2019

Identification of a novel basic helix-loop-helix-PAS factor, NXF, reveals a Sim2 competitive, positive regulatory role in dendritic-cytoskeleton modulator drebrin gene expression

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IUM7

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IUM7

determination method or standard

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8IUM7

Myc-type, basic helix-loop-helix (bHLH) domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8IUM7

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8IUM7

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000311196

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000311196

ENSP00000433135

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000433135

ENSP00000492526

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000492526

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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