G protein-coupled receptor 183 (Q21118967)

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mammalian protein found in Homo sapiens

epstein-Barr virus-induced G-protein coupled receptor 2
EBI2
GPR183
Epstein-Barr virus induced gene 2 (lymphocyte-specific G protein-coupled receptor)
EBV-induced G-protein coupled receptor 2
G-protein coupled receptor 183

Language	Label	Description	Also known as
English	G protein-coupled receptor 183	mammalian protein found in Homo sapiens	epstein-Barr virus-induced G-protein coupled receptor 2 EBI2 GPR183 Epstein-Barr virus induced gene 2 (lymphocyte-specific G protein-coupled receptor) EBV-induced G-protein coupled receptor 2 G-protein coupled receptor 183

Statements

1 reference

13 November 2019

UniProt protein ID

G protein-coupled receptor, rhodopsin-like

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P32249

GPCR, rhodopsin-like, 7TM, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

signal transducer activity

determination method

1 reference

27 February 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32249&geneProductId=UniProtKB:P32249

determination method

oxysterol binding

determination method

5 references

8 April 2019

Identification and characterization of small molecule modulators of the Epstein-Barr virus-induced gene 2 (EBI2) receptor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32249

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32249

determination method

8 April 2019

Molecular characterization of oxysterol binding to the Epstein-Barr virus-induced gene 2 (GPR183)

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32249

determination method

8 April 2019

Oxysterols direct immune cell migration via EBI2

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32249

determination method

8 April 2019

Identification of structural motifs critical for epstein-barr virus-induced molecule 2 function and homology modeling of the ligand docking site

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32249

determination method

G protein-coupled receptor activity

determination method

6 references

27 February 2018

Epstein-Barr virus-induced genes: first lymphocyte-specific G protein-coupled peptide receptors

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32249&geneProductId=UniProtKB:P32249

determination method

27 February 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32249&geneProductId=UniProtKB:P32249

determination method

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32249&geneProductId=UniProtKB:P32249

determination method

27 February 2018

Identification of structural motifs critical for epstein-barr virus-induced molecule 2 function and homology modeling of the ligand docking site

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32249&geneProductId=UniProtKB:P32249

determination method

27 February 2018

Molecular characterization of oxysterol binding to the Epstein-Barr virus-induced gene 2 (GPR183)

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32249&geneProductId=UniProtKB:P32249

determination method

27 February 2018

Structural motifs of importance for the constitutive activity of the orphan 7TM receptor EBI2: analysis of receptor activation in the absence of an agonist

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32249&geneProductId=UniProtKB:P32249

determination method

G protein-coupled receptor activity

determination method

7 references

8 April 2019

Epstein-Barr virus-induced genes: first lymphocyte-specific G protein-coupled peptide receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32249

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32249

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32249

determination method

8 April 2019

Structural motifs of importance for the constitutive activity of the orphan 7TM receptor EBI2: analysis of receptor activation in the absence of an agonist

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32249

determination method

8 April 2019

Molecular characterization of oxysterol binding to the Epstein-Barr virus-induced gene 2 (GPR183)

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32249

determination method

8 April 2019

Identification of structural motifs critical for epstein-barr virus-induced molecule 2 function and homology modeling of the ligand docking site

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32249

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32249

determination method

integral component of plasma membrane

determination method

1 reference

8 April 2019

Epstein-Barr virus-induced genes: first lymphocyte-specific G protein-coupled peptide receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32249

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32249

determination method

plasma membrane

determination method

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32249

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32249

determination method

8 April 2019

Structural motifs of importance for the constitutive activity of the orphan 7TM receptor EBI2: analysis of receptor activation in the absence of an agonist

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32249

determination method

8 April 2019

Identification of structural motifs critical for epstein-barr virus-induced molecule 2 function and homology modeling of the ligand docking site

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32249

determination method

8 April 2019

Ligand modulation of the Epstein-Barr virus-induced seven-transmembrane receptor EBI2: identification of a potent and efficacious inverse agonist

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32249

determination method

biological process

G protein-coupled receptor signaling pathway

determination method

8 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32249

determination method

8 April 2019

Epstein-Barr virus-induced genes: first lymphocyte-specific G protein-coupled peptide receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32249

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32249

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32249

determination method

8 April 2019

Identification of structural motifs critical for epstein-barr virus-induced molecule 2 function and homology modeling of the ligand docking site

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32249

determination method

8 April 2019

Structural motifs of importance for the constitutive activity of the orphan 7TM receptor EBI2: analysis of receptor activation in the absence of an agonist

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32249

determination method

8 April 2019

Molecular characterization of oxysterol binding to the Epstein-Barr virus-induced gene 2 (GPR183)

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32249

determination method

8 April 2019

Ligand modulation of the Epstein-Barr virus-induced seven-transmembrane receptor EBI2: identification of a potent and efficacious inverse agonist

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32249

determination method

B cell activation involved in immune response

determination method

1 reference

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32249&geneProductId=UniProtKB:P32249

determination method

immune response

determination method

1 reference

8 April 2019

Epstein-Barr virus-induced genes: first lymphocyte-specific G protein-coupled peptide receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32249

determination method

signal transduction

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32249

determination method

positive regulation of ERK1 and ERK2 cascade

determination method

immune system process

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32249

determination method

regulation of astrocyte chemotaxis

determination method

1 reference

8 April 2019

EBI2 regulates intracellular signaling and migration in human astrocyte

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32249

determination method

adaptive immune response

determination method

cell chemotaxis

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32249

determination method

physically interacts with

(25R)-cholest-5-ene-3β,26-diol

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

7alpha-hydroxycholesterol

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

GPCR, rhodopsin-like, 7TM

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P32249

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000365596

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000365596

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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