Mastermind like transcriptional coactivator 1 (Q21119393)

transcription coactivator activity

IPI

3 references

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92585&geneProductId=UniProtKB:Q92585

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92585&geneProductId=UniProtKB:Q92585

31 January 2018

MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92585&geneProductId=UniProtKB:Q92585

10 references

8 April 2019

A human protein with sequence similarity to Drosophila mastermind coordinates the nuclear form of notch and a CSL protein to build a transcriptional activator complex on target promoters

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92585

8 April 2019

Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92585

8 April 2019

MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92585

8 April 2019

The Notch coactivator, MAML1, functions as a novel coactivator for MEF2C-mediated transcription and is required for normal myogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92585

8 April 2019

Notch signaling mediates hypoxia-induced tumor cell migration and invasion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92585

8 April 2019

Direct inhibition of the NOTCH transcription factor complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92585

8 April 2019

Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92585

8 April 2019

NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92585

8 April 2019

Structural and mechanistic insights into cooperative assembly of dimeric Notch transcription complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92585

8 April 2019

Conformational Locking upon Cooperative Assembly of Notch Transcription Complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92585

Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover

IPI

protein kinase binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92585

transcription coactivator activity

IPI

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92585

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92585

8 April 2019

MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92585

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92585

intracellular membrane-bounded organelle

IBA

cell component

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92585

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92585

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92585

8 April 2019

MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92585

8 April 2019

CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92585

8 April 2019

The Notch coactivator, MAML1, functions as a novel coactivator for MEF2C-mediated transcription and is required for normal myogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92585

MAML1-RBP-Jkappa- ICN1 complex

1 reference

8 April 2019

The Notch coactivator, MAML1, functions as a novel coactivator for MEF2C-mediated transcription and is required for normal myogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92585

Notch signaling pathway

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92585

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92585

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92585

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92585

8 April 2019

MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92585

atrioventricular node development

1 reference

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92585

regulation of transcription, DNA-templated

ISS

1 reference

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92585&geneProductId=UniProtKB:Q92585

positive regulation of muscle cell differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92585

transcription, DNA-templated

1 reference

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92585&geneProductId=UniProtKB:Q92585

The Notch coactivator, MAML1, functions as a novel coactivator for MEF2C-mediated transcription and is required for normal myogenesis

protein phosphorylation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92585

myoblast differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92585

transcription initiation from RNA polymerase II promoter

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92585

positive regulation of transcription by RNA polymerase II

TAS

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92585

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92585

8 April 2019

MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92585

8 April 2019

The Notch coactivator, MAML1, functions as a novel coactivator for MEF2C-mediated transcription and is required for normal myogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92585

positive regulation of transcription of Notch receptor target

positive regulation of Notch signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92585

Neurogenic mastermind-like, N-terminal

TAS

has part(s)

1 reference

stated in

InterPro Release 71.0