Programmed cell death 5 (Q21119690)

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mammalian protein found in Homo sapiens

TFAR19 novel apoptosis-related
TF-1 cell apoptosis-related protein 19
Protein TFAR19
PDCD5
TF1 cell apoptosis-related gene 19
programmed cell death protein 5

Language	Label	Description	Also known as
English	Programmed cell death 5	mammalian protein found in Homo sapiens	TFAR19 novel apoptosis-related TF-1 cell apoptosis-related protein 19 Protein TFAR19 PDCD5 TF1 cell apoptosis-related gene 19 programmed cell death protein 5

Statements

1 reference

13 November 2019

UniProt protein ID

PDCD5-like superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O14737

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O14737

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14737

determination method

heparin binding

determination method

1 reference

8 April 2019

Studies on interactions of programmed cell death 5 (PDCD5) and its related peptides with heparin by capillary zone electrophoresis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14737

determination method

protein binding

determination method

acetyltransferase activator activity

determination method

1 reference

8 April 2019

PDCD5 negatively regulates autoimmunity by upregulating FOXP3(+) regulatory T cells and suppressing Th17 and Th1 responses

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14737

determination method

beta-tubulin binding

determination method

1 reference

8 April 2019

Programmed cell death protein 5 interacts with the cytosolic chaperonin containing tailless complex polypeptide 1 (CCT) to regulate β-tubulin folding

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14737

determination method

determination method

1 reference

26 September 2017

Dynamic proteomics in individual human cells uncovers widespread cell-cycle dependence of nuclear proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14737&geneProductId=UniProtKB:O14737

determination method

extracellular exosome

determination method

1 reference

26 September 2017

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14737&geneProductId=UniProtKB:O14737

determination method

determination method

1 reference

26 September 2017

PDCD5 negatively regulates autoimmunity by upregulating FOXP3(+) regulatory T cells and suppressing Th17 and Th1 responses

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14737&geneProductId=UniProtKB:O14737

determination method

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14737

determination method

determination method

1 reference

8 April 2019

Dynamic proteomics in individual human cells uncovers widespread cell-cycle dependence of nuclear proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14737

determination method

extracellular exosome

determination method

1 reference

8 April 2019

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14737

determination method

biological process

cellular response to transforming growth factor beta stimulus

determination method

1 reference

8 April 2019

PDCD5 negatively regulates autoimmunity by upregulating FOXP3(+) regulatory T cells and suppressing Th17 and Th1 responses

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14737

determination method

negative regulation of chaperone-mediated protein folding

determination method

1 reference

8 April 2019

Programmed cell death protein 5 interacts with the cytosolic chaperonin containing tailless complex polypeptide 1 (CCT) to regulate β-tubulin folding

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14737

determination method

positive regulation of release of cytochrome c from mitochondria

determination method

1 reference

8 April 2019

Short interfering RNA against the PDCD5 attenuates cell apoptosis and caspase-3 activity induced by Bax overexpression

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14737

determination method

apoptotic process

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14737

determination method

positive regulation of cysteine-type endopeptidase activity involved in apoptotic process

determination method

1 reference

8 April 2019

Short interfering RNA against the PDCD5 attenuates cell apoptosis and caspase-3 activity induced by Bax overexpression

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14737

determination method

positive regulation of gene expression

determination method

1 reference

8 April 2019

PDCD5 negatively regulates autoimmunity by upregulating FOXP3(+) regulatory T cells and suppressing Th17 and Th1 responses

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14737

determination method

positive regulation of protein insertion into mitochondrial outer membrane

determination method

1 reference

8 April 2019

Short interfering RNA against the PDCD5 attenuates cell apoptosis and caspase-3 activity induced by Bax overexpression

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14737

determination method

negative regulation of cell population proliferation

determination method

1 reference

8 April 2019

Short interfering RNA against the PDCD5 attenuates cell apoptosis and caspase-3 activity induced by Bax overexpression

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14737

determination method

positive regulation of apoptotic process

determination method

1 reference

8 April 2019

TFAR19, a novel apoptosis-related gene cloned from human leukemia cell line TF-1, could enhance apoptosis of some tumor cells induced by growth factor withdrawal

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14737

determination method

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000466214

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000466214

ENSP00000476525

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000476525

ENSP00000221784

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000221784

ENSP00000368620

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000368620

ENSP00000467737

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000467737

ENSP00000468741

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000468741

PDB structure ID

1 reference

UniProt protein ID

20 March 2016

language of work or name

1 reference

UniProt protein ID

20 March 2016

language of work or name

1 reference

UniProt protein ID

20 March 2016

language of work or name

Sitelinks

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Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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