HPS4 biogenesis of lysosomal organelles complex 3 subunit 2 (Q21119770)

http://www.ebi.ac.uk/interpro/protein/Q9NQG7

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

31 October 2017

BLOC-3, a protein complex containing the Hermansky-Pudlak syndrome gene products HPS1 and HPS4

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG7&geneProductId=UniProtKB:Q9NQG7

protein homodimerization activity

IPI

1 reference

31 October 2017

The Hermansky-Pudlak syndrome 1 (HPS1) and HPS4 proteins are components of two complexes, BLOC-3 and BLOC-4, involved in the biogenesis of lysosome-related organelles

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG7&geneProductId=UniProtKB:Q9NQG7

protein dimerization activity

IPI

1 reference

31 October 2017

The Hermansky-Pudlak syndrome 1 (HPS1) and HPS4 proteins are components of two complexes, BLOC-3 and BLOC-4, involved in the biogenesis of lysosome-related organelles

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG7&geneProductId=UniProtKB:Q9NQG7

1 reference

31 October 2017

BLOC-3, a protein complex containing the Hermansky-Pudlak syndrome gene products HPS1 and HPS4

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG7&geneProductId=UniProtKB:Q9NQG7

1 reference

31 October 2017

The Hermansky-Pudlak syndrome 1 (HPS1) and HPS4 proteins are components of two complexes, BLOC-3 and BLOC-4, involved in the biogenesis of lysosome-related organelles

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG7&geneProductId=UniProtKB:Q9NQG7

BLOC-3, a protein complex containing the Hermansky-Pudlak syndrome gene products HPS1 and HPS4

IDA

platelet dense granule

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG7&geneProductId=UniProtKB:Q9NQG7

1 reference

31 October 2017

The Hermansky-Pudlak syndrome 1 (HPS1) and HPS4 proteins are components of two complexes, BLOC-3 and BLOC-4, involved in the biogenesis of lysosome-related organelles

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG7&geneProductId=UniProtKB:Q9NQG7

3 references

31 October 2017

Assembly of the biogenesis of lysosome-related organelles complex-3 (BLOC-3) and its interaction with Rab9

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG7&geneProductId=UniProtKB:Q9NQG7

31 October 2017

BLOC-3 mutated in Hermansky-Pudlak syndrome is a Rab32/38 guanine nucleotide exchange factor

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG7&geneProductId=UniProtKB:Q9NQG7

31 October 2017

BLOC-3, a protein complex containing the Hermansky-Pudlak syndrome gene products HPS1 and HPS4

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG7&geneProductId=UniProtKB:Q9NQG7

1 reference

31 October 2017

BLOC-3, a protein complex containing the Hermansky-Pudlak syndrome gene products HPS1 and HPS4

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG7&geneProductId=UniProtKB:Q9NQG7

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG7&geneProductId=UniProtKB:Q9NQG7

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG7&geneProductId=UniProtKB:Q9NQG7

1 reference

31 October 2017

Hermansky-Pudlak syndrome is caused by mutations in HPS4, the human homolog of the mouse light-ear gene

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG7&geneProductId=UniProtKB:Q9NQG7

1 reference

31 October 2017

The Hermansky-Pudlak syndrome 1 (HPS1) and HPS4 proteins are components of two complexes, BLOC-3 and BLOC-4, involved in the biogenesis of lysosome-related organelles

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG7&geneProductId=UniProtKB:Q9NQG7

The Hermansky-Pudlak syndrome 1 (HPS1) and HPS4 proteins are components of two complexes, BLOC-3 and BLOC-4, involved in the biogenesis of lysosome-related organelles

IDA

protein stabilization

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG7&geneProductId=UniProtKB:Q9NQG7

The Hermansky-Pudlak syndrome 1 (HPS1) and HPS4 proteins are components of two complexes, BLOC-3 and BLOC-4, involved in the biogenesis of lysosome-related organelles

IPI

lysosome organization

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG7&geneProductId=UniProtKB:Q9NQG7

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG7&geneProductId=UniProtKB:Q9NQG7

melanocyte differentiation

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG7&geneProductId=UniProtKB:Q9NQG7

organelle organization

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG7&geneProductId=UniProtKB:Q9NQG7

positive regulation of eye pigmentation

1 reference

31 October 2017

Hermansky-Pudlak syndrome is caused by mutations in HPS4, the human homolog of the mouse light-ear gene

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG7&geneProductId=UniProtKB:Q9NQG7

positive regulation of protein targeting to mitochondrion

TAS

1 reference

31 October 2017

High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy

GOA

curator

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG7&geneProductId=UniProtKB:Q9NQG7

1 reference

31 October 2017

BLOC-3 mutated in Hermansky-Pudlak syndrome is a Rab32/38 guanine nucleotide exchange factor

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG7&geneProductId=UniProtKB:Q9NQG7

regulation of molecular function

IDA

1 reference

31 October 2017

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG7&geneProductId=UniProtKB:Q9NQG7