Leukocyte immunoglobulin-like receptor subfamily B member 2 (Q21120800)

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human protein (annotated by UniProtKB/Swiss-Prot Q8N423)
  • ILT-4
  • Monocyte/macrophage immunoglobulin-like receptor 10
  • MIR-10
  • CD85 antigen-like family member D
  • Immunoglobulin-like transcript 4
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Language Label Description Also known as
English
Leukocyte immunoglobulin-like receptor subfamily B member 2
human protein (annotated by UniProtKB/Swiss-Prot Q8N423)
  • ILT-4
  • Monocyte/macrophage immunoglobulin-like receptor 10
  • MIR-10
  • CD85 antigen-like family member D
  • Immunoglobulin-like transcript 4

Statements

instance of
protein
0 references
molecular function
protein binding
determination method
IPI
14 references
retrieved
8 April 2019
stated in
Inhibitory immunoglobulin-like receptors LILRB and PIR-B negatively regulate osteoclast development
GOA
curator
UniProt
UniProt protein ID
Q8N423
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N423
determination method
IPI
retrieved
8 April 2019
stated in
Functional characterization of HLA-F and binding of HLA-F tetramers to ILT2 and ILT4 receptors
GOA
curator
UniProt
UniProt protein ID
Q8N423
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N423
determination method
IPI
retrieved
8 April 2019
stated in
Human inhibitory receptors Ig-like transcript 2 (ILT2) and ILT4 compete with CD8 for MHC class I binding and bind preferentially to HLA-G
GOA
curator
UniProt
UniProt protein ID
Q8N423
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N423
determination method
IPI
retrieved
8 April 2019
stated in
Multimeric structures of HLA-G isoforms function through differential binding to LILRB receptors
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N423
determination method
IPI
retrieved
8 April 2019
stated in
Inhibitory receptors bind ANGPTLs and support blood stem cells and leukaemia development
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N423
determination method
IPI
retrieved
8 April 2019
stated in
Inhibitory immunoglobulin-like receptors LILRB and PIR-B negatively regulate osteoclast development
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N423
determination method
IPI
retrieved
8 April 2019
stated in
Structural basis for recognition of the nonclassical MHC molecule HLA-G by the leukocyte Ig-like receptor B2 (LILRB2/LIR2/ILT4/CD85d)
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N423
determination method
IPI
retrieved
8 April 2019
stated in
Efficient leukocyte Ig-like receptor signaling and crystal structure of disulfide-linked HLA-G dimer.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N423
determination method
IPI
retrieved
8 April 2019
stated in
Real-Time Analysis of Binding Events between Different Aβ1-42 Species and Human Lilrb2 by Dual Polarization Interferometry.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N423
determination method
IPI
retrieved
8 April 2019
stated in
A motif in LILRB2 critical for Angptl2 binding and activation.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N423
determination method
IPI
retrieved
8 April 2019
stated in
Human LilrB2 is a β-amyloid receptor and its murine homolog PirB regulates synaptic plasticity in an Alzheimer's model
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N423
determination method
IPI
retrieved
8 April 2019
stated in
Cutting Edge: Class II-like Structural Features and Strong Receptor Binding of the Nonclassical HLA-G2 Isoform Homodimer.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N423
determination method
IPI
retrieved
8 April 2019
stated in
Angiopoietin-like proteins stimulate HSPC development through interaction with notch receptor signaling
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N423
determination method
IPI
retrieved
8 April 2019
stated in
HLA-F and MHC-I Open Conformers Bind Natural Killer Cell Ig-Like Receptor KIR3DS1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N423
determination method
IPI
MHC class I protein binding
determination method
IDA
IPI
6 references
retrieved
8 April 2019
stated in
Multimeric structures of HLA-G isoforms function through differential binding to LILRB receptors
GOA
curator
UniProt
UniProt protein ID
Q8N423
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N423
determination method
IPI
retrieved
8 April 2019
stated in
Ig-like transcript 4 inhibits lipid antigen presentation through direct CD1d interaction
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N423
determination method
IPI
retrieved
8 April 2019
stated in
Soluble HLA-G inhibits myeloid dendritic cell function in HIV-1 infection by interacting with leukocyte immunoglobulin-like receptor B2
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N423
determination method
IPI
retrieved
8 April 2019
stated in
Inhibitory immunoglobulin-like receptors LILRB and PIR-B negatively regulate osteoclast development
GOA
curator
UniProt
UniProt protein ID
Q8N423
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N423
determination method
IDA
retrieved
8 April 2019
stated in
The MHC class I binding proteins LIR-1 and LIR-2 inhibit Fc receptor-mediated signaling in monocytes
GOA
curator
UniProt
UniProt protein ID
Q8N423
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N423
determination method
IDA
retrieved
8 April 2019
stated in
Interleukin 10 regulates cell surface and soluble LIR-2 (CD85d) expression on dendritic cells resulting in T cell hyporesponsiveness in vitro
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N423
determination method
IDA
cell component
biological process

Identifiers

 
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