Poly(ADP-ribose) polymerase family member 10 (Q21121002)

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mammalian protein found in Homo sapiens

ADP-ribosyltransferase diphtheria toxin-like 10
poly [ADP-ribose] polymerase 10
ARTD10
protein mono-ADP-ribosyltransferase PARP10
PARP10

Language	Label	Description	Also known as
English	Poly(ADP-ribose) polymerase family member 10	mammalian protein found in Homo sapiens	ADP-ribosyltransferase diphtheria toxin-like 10 poly [ADP-ribose] polymerase 10 ARTD10 protein mono-ADP-ribosyltransferase PARP10 PARP10

Statements

1 reference

13 November 2019

UniProt protein ID

Nucleotide-binding alpha-beta plait domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q53GL7

PARP-10, RNA recognition motif 1 and 2, protein family

1 reference

based on heuristic

inferred from protein domain or family

Poly(ADP-ribose) polymerase, catalytic domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

transferase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

determination method

K63-linked polyubiquitin modification-dependent protein binding

determination method

1 reference

8 April 2019

Regulation of NF-κB signalling by the mono-ADP-ribosyltransferase ARTD10

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

determination method

protein binding

determination method

5 references

8 April 2019

PARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

determination method

8 April 2019

The ADP-ribosyltransferase PARP10/ARTD10 interacts with proliferating cell nuclear antigen (PCNA) and is required for DNA damage tolerance

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

determination method

8 April 2019

Recognition of mono-ADP-ribosylated ARTD10 substrates by ARTD8 macrodomains

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

determination method

8 April 2019

The interaction between the PARP10 protein and the NS1 protein of H5N1 AIV and its effect on virus replication

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

determination method

8 April 2019

Deficiency of terminal ADP-ribose protein glycohydrolase TARG1/C6orf130 in neurodegenerative disease

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

determination method

glycosyltransferase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

determination method

NAD+ ADP-ribosyltransferase activity

determination method

4 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q53GL7&geneProductId=UniProtKB:Q53GL7

determination method

1 January 2018

Recognition of mono-ADP-ribosylated ARTD10 substrates by ARTD8 macrodomains

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q53GL7&geneProductId=UniProtKB:Q53GL7

determination method

1 January 2018

Regulation of NF-κB signalling by the mono-ADP-ribosyltransferase ARTD10

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q53GL7&geneProductId=UniProtKB:Q53GL7

determination method

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q53GL7&geneProductId=UniProtKB:Q53GL7

determination method

protein ADP-ribosylase activity

determination method

3 references

8 April 2019

The ADP-ribosyltransferase PARP10/ARTD10 interacts with proliferating cell nuclear antigen (PCNA) and is required for DNA damage tolerance

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

determination method

8 April 2019

Family-wide analysis of poly(ADP-ribose) polymerase activity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

determination method

8 April 2019

Substrate-assisted catalysis by PARP10 limits its activity to mono-ADP-ribosylation.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

determination method

NAD+ ADP-ribosyltransferase activity

determination method

3 references

8 April 2019

Recognition of mono-ADP-ribosylated ARTD10 substrates by ARTD8 macrodomains

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

determination method

8 April 2019

Regulation of NF-κB signalling by the mono-ADP-ribosyltransferase ARTD10

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

determination method

determination method

4 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

determination method

8 April 2019

PARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

determination method

8 April 2019

Recognition of mono-ADP-ribosylated ARTD10 substrates by ARTD8 macrodomains

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

determination method

8 April 2019

The interaction between the PARP10 protein and the NS1 protein of H5N1 AIV and its effect on virus replication

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

determination method

determination method

4 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

determination method

8 April 2019

PARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

determination method

8 April 2019

Recognition of mono-ADP-ribosylated ARTD10 substrates by ARTD8 macrodomains

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

determination method

8 April 2019

The interaction between the PARP10 protein and the NS1 protein of H5N1 AIV and its effect on virus replication

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

determination method

determination method

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

determination method

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

determination method

intracellular membrane-bounded organelle

determination method

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

determination method

biological process

negative regulation of protein K63-linked ubiquitination

determination method

1 reference

8 April 2019

Regulation of NF-κB signalling by the mono-ADP-ribosyltransferase ARTD10

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

determination method

protein auto-ADP-ribosylation

determination method

1 reference

7 November 2018

Regulation of NF-κB signalling by the mono-ADP-ribosyltransferase ARTD10

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q53GL7&geneProductId=UniProtKB:Q53GL7

determination method

negative regulation of NF-kappaB transcription factor activity

determination method

1 reference

8 April 2019

Regulation of NF-κB signalling by the mono-ADP-ribosyltransferase ARTD10

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

determination method

protein ADP-ribosylation

determination method

1 reference

8 April 2019

Regulation of NF-κB signalling by the mono-ADP-ribosyltransferase ARTD10

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

determination method

negative regulation of fibroblast proliferation

determination method

1 reference

8 April 2019

PARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

determination method

negative regulation of gene expression

determination method

1 reference

8 April 2019

Regulation of NF-κB signalling by the mono-ADP-ribosyltransferase ARTD10

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

determination method

NAD biosynthesis via nicotinamide riboside salvage pathway

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

determination method

translesion synthesis

determination method

1 reference

8 April 2019

The ADP-ribosyltransferase PARP10/ARTD10 interacts with proliferating cell nuclear antigen (PCNA) and is required for DNA damage tolerance

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

determination method

protein auto-ADP-ribosylation

determination method

3 references

8 April 2019

Regulation of NF-κB signalling by the mono-ADP-ribosyltransferase ARTD10

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

determination method

8 April 2019

Family-wide analysis of poly(ADP-ribose) polymerase activity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

determination method

8 April 2019

Substrate-assisted catalysis by PARP10 limits its activity to mono-ADP-ribosylation.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

determination method

cellular response to DNA damage stimulus

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

determination method

poly(ADP-ribose) polymerase, catalytic domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q53GL7

PARP-10, RNA recognition motif 1 and 2

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q53GL7

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000325618

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000325618

ENSP00000314320

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000314320

ENSP00000431250

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000431250

ENSP00000431620

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000431620

ENSP00000431818

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000431818

ENSP00000432204

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000432204

ENSP00000432733

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000432733

ENSP00000433990

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000433990

ENSP00000434005

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000434005

ENSP00000434411

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000434411

ENSP00000434776

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000434776

ENSP00000435161

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000435161

ENSP00000435793

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000435793

ENSP00000436301

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000436301

ENSP00000436333

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000436333

ENSP00000436697

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000436697

PDB structure ID

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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