DNA topoisomerase III alpha (Q21121455)

DNA topoisomerase, type IA, central region, subdomain 2

1 reference

DNA topoisomerase, type IA, core domain

1 reference

DNA topoisomerase, type IA, central region, subdomain 1

1 reference

DNA topoisomerase, type IA, central region, subdomain 3

1 reference

DNA topoisomerase, type IA, DNA-binding domain, protein family

1 reference

DNA topoisomerase, type IA, zn finger, protein family

1 reference

Zinc finger, GRF-type, protein family

1 reference

DNA topoisomerase 3-like, TOPRIM domain, protein family

1 reference

DNA topoisomerase, type IA, domain 2, protein family

1 reference

TOPRIM domain, protein family

1 reference

DNA topoisomerase, type IA, central domain, protein family

1 reference

DNA topoisomerase, type IA, active site, protein family

1 reference

1 reference

13 November 2019

1 reference

13 November 2019

zinc ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472

1 reference

8 April 2019

protein binding

8 references

8 April 2019

Association of the Bloom syndrome protein with topoisomerase IIIalpha in somatic and meiotic cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472

8 April 2019

Scaffolding protein SPIDR/KIAA0146 connects the Bloom syndrome helicase with homologous recombination repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472

8 April 2019

BLAP75, an essential component of Bloom's syndrome protein complexes that maintain genome integrity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472

8 April 2019

BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediates

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472

8 April 2019

Systematic analysis of human protein complexes identifies chromosome segregation proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472

8 April 2019

Rif1 provides a new DNA-binding interface for the Bloom syndrome complex to maintain normal replication

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472

8 April 2019

Structural and mechanistic insight into Holliday-junction dissolution by Topoisomerase IIIα and RMI1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472

8 April 2019

Crystal structures of RMI1 and RMI2, two OB-fold regulatory subunits of the BLM complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472

isomerase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472

1 reference

8 April 2019

metal ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472

1 reference

8 April 2019

DNA topoisomerase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472

8 April 2019

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472

single-stranded DNA binding

IBA

1 reference

8 April 2019

Topoisomerase 3α Is Required for Decatenation and Segregation of Human mtDNA.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472

cell component

PML body

1 reference

8 April 2019

Association of the Bloom syndrome protein with topoisomerase IIIalpha in somatic and meiotic cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472

nucleoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472

1 reference

8 April 2019

chromosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472

1 reference

8 April 2019

nucleus

1 reference

24 April 2018

Human TOP3: a single-copy gene encoding DNA topoisomerase III

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13472&geneProductId=UniProtKB:Q13472

mitochondrion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472

1 reference

8 April 2019

mitochondrial matrix

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472

1 reference

8 April 2019

biological process

DNA replication

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472

1 reference

8 April 2019

meiosis

1 reference

8 April 2019

Human TOP3: a single-copy gene encoding DNA topoisomerase III

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472

DNA topological change

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472

3 references

8 April 2019

8 April 2019

Human topoisomerase IIIalpha is a single-stranded DNA decatenase that is stimulated by BLM and RMI1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472

mitochondrial DNA metabolic process

IBA

1 reference

8 April 2019

Topoisomerase 3α Is Required for Decatenation and Segregation of Human mtDNA.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472

chromosome separation

1 reference

8 April 2019

Mutations in TOP3A Cause a Bloom Syndrome-like Disorder

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472

regulation of signal transduction by p53 class mediator

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472

1 reference

8 April 2019

DNA topoisomerase, type IA, central

has part(s)

1 reference

Zinc finger, GRF-type

1 reference

TOPRIM domain

1 reference

DNA topoisomerase, type IA, zn finger

1 reference

DNA topoisomerase, type IA, active site

1 reference

DNA topoisomerase, type IA, domain 2

1 reference

DNA topoisomerase, type IA, DNA-binding domain

1 reference

DNA topoisomerase 3-like, TOPRIM domain

1 reference