Solute carrier family 1 member 4 (Q21122755)

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mammalian protein found in Homo sapiens

solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC1A4
ASCT-1
neutral amino acid transporter A
SATT
alanine/serine/cysteine/threonine transporter 1
glutamate/neutral amino acid transporter

Language	Label	Description	Also known as
English	Solute carrier family 1 member 4	mammalian protein found in Homo sapiens	solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 SLC1A4 ASCT-1 neutral amino acid transporter A SATT alanine/serine/cysteine/threonine transporter 1 glutamate/neutral amino acid transporter

Statements

1 reference

13 November 2019

UniProt protein ID

Sodium:dicarboxylate symporter superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P43007

Sodium:dicarboxylate symporter

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P43007

dicarboxylate/amino acid:cation symporter

1 reference

Transporter Classification Database ID

2 October 2019

based on heuristic

hierarchical database ID heuristic

Sodium:dicarboxylate symporter, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

L-glutamine transmembrane transporter activity

determination method

1 reference

8 April 2019

The nuclear receptor FXR regulates hepatic transport and metabolism of glutamine and glutamate

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

L-threonine transmembrane transporter activity

determination method

1 reference

8 April 2019

Cloning and expression of a novel Na(+)-dependent neutral amino acid transporter structurally related to mammalian Na+/glutamate cotransporters

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

L-proline transmembrane transporter activity

determination method

1 reference

8 April 2019

Transport of proline and hydroxyproline by the neutral amino-acid exchanger ASCT1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

L-serine transmembrane transporter activity

determination method

4 references

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

8 April 2019

Cloning and expression of a human neutral amino acid transporter with structural similarity to the glutamate transporter gene family

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

8 April 2019

Cloning and expression of a novel Na(+)-dependent neutral amino acid transporter structurally related to mammalian Na+/glutamate cotransporters

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

8 April 2019

ASCT-1 is a neutral amino acid exchanger with chloride channel activity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

L-hydroxyproline transmembrane transporter activity

determination method

1 reference

8 April 2019

Transport of proline and hydroxyproline by the neutral amino-acid exchanger ASCT1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

L-cystine transmembrane transporter activity

determination method

3 references

8 April 2019

Cloning and expression of a human neutral amino acid transporter with structural similarity to the glutamate transporter gene family

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

8 April 2019

Cloning and expression of a novel Na(+)-dependent neutral amino acid transporter structurally related to mammalian Na+/glutamate cotransporters

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

8 April 2019

ASCT-1 is a neutral amino acid exchanger with chloride channel activity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

neutral amino acid transmembrane transporter activity

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

L-alanine transmembrane transporter activity

determination method

3 references

8 April 2019

Cloning and expression of a human neutral amino acid transporter with structural similarity to the glutamate transporter gene family

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

8 April 2019

Cloning and expression of a novel Na(+)-dependent neutral amino acid transporter structurally related to mammalian Na+/glutamate cotransporters

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

8 April 2019

ASCT-1 is a neutral amino acid exchanger with chloride channel activity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

chloride channel activity

determination method

1 reference

8 April 2019

ASCT-1 is a neutral amino acid exchanger with chloride channel activity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

amino acid transmembrane transporter activity

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

integral component of membrane

determination method

3 references

8 April 2019

Cloning and expression of a human neutral amino acid transporter with structural similarity to the glutamate transporter gene family

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

plasma membrane

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

integral component of plasma membrane

determination method

1 reference

8 April 2019

ASCT-1 is a neutral amino acid exchanger with chloride channel activity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

determination method

1 reference

26 September 2017

Quantitative proteomics identifies a Dab2/integrin module regulating cell migration

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43007&geneProductId=UniProtKB:P43007

determination method

neuronal cell body

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

extracellular exosome

determination method

1 reference

26 September 2017

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43007&geneProductId=UniProtKB:P43007

determination method

determination method

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

microtubule organizing center

determination method

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

determination method

1 reference

8 April 2019

Quantitative proteomics identifies a Dab2/integrin module regulating cell migration

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

extracellular exosome

determination method

1 reference

8 April 2019

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

biological process

synaptic transmission, glutamatergic

determination method

1 reference

8 April 2019

Changes in region- and cell type-specific expression patterns of neutral amino acid transporter 1 (ASCT-1) in the anterior cingulate cortex and hippocampus in schizophrenia, bipolar disorder and major depression

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

determination method

1 reference

8 April 2019

Changes in region- and cell type-specific expression patterns of neutral amino acid transporter 1 (ASCT-1) in the anterior cingulate cortex and hippocampus in schizophrenia, bipolar disorder and major depression

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

L-alanine transport

determination method

3 references

8 April 2019

Cloning and expression of a human neutral amino acid transporter with structural similarity to the glutamate transporter gene family

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

8 April 2019

Cloning and expression of a novel Na(+)-dependent neutral amino acid transporter structurally related to mammalian Na+/glutamate cotransporters

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

8 April 2019

ASCT-1 is a neutral amino acid exchanger with chloride channel activity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

proline transport

determination method

1 reference

8 April 2019

Transport of proline and hydroxyproline by the neutral amino-acid exchanger ASCT1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

hydroxyproline transport

determination method

1 reference

8 April 2019

Transport of proline and hydroxyproline by the neutral amino-acid exchanger ASCT1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

amino acid transport

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

L-cystine transport

determination method

3 references

8 April 2019

Cloning and expression of a human neutral amino acid transporter with structural similarity to the glutamate transporter gene family

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

8 April 2019

Cloning and expression of a novel Na(+)-dependent neutral amino acid transporter structurally related to mammalian Na+/glutamate cotransporters

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

8 April 2019

ASCT-1 is a neutral amino acid exchanger with chloride channel activity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

L-serine transport

determination method

4 references

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

8 April 2019

Cloning and expression of a human neutral amino acid transporter with structural similarity to the glutamate transporter gene family

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

8 April 2019

Cloning and expression of a novel Na(+)-dependent neutral amino acid transporter structurally related to mammalian Na+/glutamate cotransporters

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

8 April 2019

ASCT-1 is a neutral amino acid exchanger with chloride channel activity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

glutamine transport

determination method

1 reference

8 April 2019

The nuclear receptor FXR regulates hepatic transport and metabolism of glutamine and glutamate

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

threonine transport

determination method

1 reference

8 April 2019

Cloning and expression of a novel Na(+)-dependent neutral amino acid transporter structurally related to mammalian Na+/glutamate cotransporters

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

chloride transmembrane transport

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

amino acid transmembrane transport

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

proline transmembrane transport

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

transmembrane transport

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43007

determination method

chloride transport

determination method

1 reference

26 September 2017

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43007&geneProductId=UniProtKB:P43007

determination method

determination method

1 reference

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43007&geneProductId=UniProtKB:P43007

determination method

Sodium:dicarboxylate symporter, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P43007

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000234256

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000234256

ENSP00000431942

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000431942

Transporter Classification Database ID

2 references

Transporter Classification database

13 March 2020

Transporter Classification database

29 April 2020

Sitelinks

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Wikisource(0 entries)

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Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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