Ubiquitin recognition factor in ER associated degradation 1 (Q21123565)

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mammalian protein found in Homo sapiens

UFD1
ubiquitin recognition factor in ER-associated degradation protein 1
UB fusion protein 1
UFD1L
ubiquitin fusion degradation 1 like
ubiquitin fusion degradation protein 1 homolog

Language	Label	Description	Also known as
English	Ubiquitin recognition factor in ER associated degradation 1	mammalian protein found in Homo sapiens	UFD1 ubiquitin recognition factor in ER-associated degradation protein 1 UB fusion protein 1 UFD1L ubiquitin fusion degradation 1 like ubiquitin fusion degradation protein 1 homolog

Statements

1 reference

13 November 2019

UniProt protein ID

Ubiquitin fusion degradation protein Ufd1-like

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q92890

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92890

determination method or standard

K48-linked polyubiquitin modification-dependent protein binding

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92890

determination method or standard

signaling receptor binding

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92890

determination method or standard

protein binding

determination method or standard

6 references

8 April 2019

Ufd1 is a cofactor of gp78 and plays a key role in cholesterol metabolism by regulating the stability of HMG-CoA reductase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92890

determination method or standard

8 April 2019

UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92890

determination method or standard

8 April 2019

Characterization of an Additional Binding Surface on the p97 N-Terminal Domain Involved in Bipartite Cofactor Interactions

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92890

determination method or standard

8 April 2019

Imbalances in p97 co-factor interactions in human proteinopathy

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92890

determination method or standard

8 April 2019

Hierarchical binding of cofactors to the AAA ATPase p97

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92890

determination method or standard

8 April 2019

Cloning and characterization of the gene encoding human NPL4, a protein interacting with the ubiquitin fusion-degradation protein (UFD1L)

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92890

determination method or standard

thiol-dependent deubiquitinase

determination method or standard

1 reference

8 April 2019

UFD1L, a developmentally expressed ubiquitination gene, is deleted in CATCH 22 syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92890

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92890

determination method or standard

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92890

determination method or standard

endoplasmic reticulum

determination method or standard

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92890

determination method or standard

VCP-NPL4-UFD1 AAA ATPase complex

determination method or standard

3 references

8 April 2019

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92890

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92890

determination method or standard

8 April 2019

A non-canonical role of the p97 complex in RIG-I antiviral signaling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92890

determination method or standard

biological process

error-free translesion synthesis

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92890

determination method or standard

skeletal system development

determination method or standard

1 reference

8 April 2019

A molecular pathway revealing a genetic basis for human cardiac and craniofacial defects

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92890

determination method or standard

retrograde protein transport, ER to cytosol

determination method or standard

1 reference

8 April 2019

Identification of ERAD components essential for dislocation of the null Hong Kong variant of α-1-antitrypsin (NHK)

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92890

determination method or standard

ER-associated misfolded protein catabolic process

determination method or standard

1 reference

8 April 2019

Caveolin-1 interacts with Derlin-1 and promotes ubiquitination and degradation of cyclooxygenase-2 via collaboration with p97 complex

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92890

determination method or standard

proteasome-mediated ubiquitin-dependent protein catabolic process

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92890

determination method or standard

ubiquitin-dependent protein catabolic process

determination method or standard

3 references

8 April 2019

UFD1L, a developmentally expressed ubiquitination gene, is deleted in CATCH 22 syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92890

determination method or standard

8 April 2019

A non-canonical role of the p97 complex in RIG-I antiviral signaling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92890

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92890

determination method or standard

protein deubiquitination

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92890

determination method or standard

negative regulation of type I interferon production

determination method or standard

1 reference

8 April 2019

A non-canonical role of the p97 complex in RIG-I antiviral signaling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92890

determination method or standard

negative regulation of RIG-I signaling pathway

determination method or standard

1 reference

8 April 2019

A non-canonical role of the p97 complex in RIG-I antiviral signaling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92890

determination method or standard

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000263202

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000263202

ENSP00000382439

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000382439

ENSP00000402136

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000402136

ENSP00000406680

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000406680

ENSP00000418295

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000418295

ENSP00000418390

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000418390

PDB structure ID

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

Sitelinks

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Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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