UDP glucuronosyltransferase family 1 member A10 (Q21123568)

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mammalian protein found in Homo sapiens

UDP-glucuronosyltransferase 1-10
UDP-glucuronosyltransferase 1A1
UGT-1J
UDP-glucuronosyltransferase 1-1
UDP-glucuronosyltransferase 1-A
UDP-glucuronosyltransferase 1A10
UDPGT 1-1
UDP glucuronosyltransferase 1 family, polypeptide A10
UGT1J
Bilirubin-specific UDPGT isozyme 1
UDP glycosyltransferase 1 family, polypeptide A10
UGT1A10
UDPGT 1-10
UDP-glucuronosyltransferase 1-J

Language	Label	Description	Also known as
English	UDP glucuronosyltransferase family 1 member A10	mammalian protein found in Homo sapiens	UDP-glucuronosyltransferase 1-10 UDP-glucuronosyltransferase 1A1 UGT-1J UDP-glucuronosyltransferase 1-1 UDP-glucuronosyltransferase 1-A UDP-glucuronosyltransferase 1A10 UDPGT 1-1 UDP glucuronosyltransferase 1 family, polypeptide A10 UGT1J Bilirubin-specific UDPGT isozyme 1 UDP glycosyltransferase 1 family, polypeptide A10 UGT1A10 UDPGT 1-10 UDP-glucuronosyltransferase 1-J

Statements

1 reference

13 November 2019

UniProt protein ID

UDP-glucuronosyl/UDP-glucosyltransferase

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9HAW8

UDP-glycosyltransferase family, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

transferase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAW8

determination method

retinoic acid binding

determination method

1 reference

8 April 2019

Role of UDP-glucuronosyltransferase isoforms in 13-cis retinoic acid metabolism in humans

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAW8

determination method

hexosyltransferase activity

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAW8

determination method

protein homodimerization activity

determination method

1 reference

8 April 2019

Oligomerization of the UDP-glucuronosyltransferase 1A proteins: homo- and heterodimerization analysis by fluorescence resonance energy transfer and co-immunoprecipitation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAW8

determination method

glycosyltransferase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAW8

determination method

protein heterodimerization activity

determination method

2 references

27 March 2018

Alternatively spliced products of the UGT1A gene interact with the enzymatically active proteins to inhibit glucuronosyltransferase activity in vitro

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HAW8&geneProductId=UniProtKB:Q9HAW8

determination method

27 March 2018

Oligomerization of the UDP-glucuronosyltransferase 1A proteins: homo- and heterodimerization analysis by fluorescence resonance energy transfer and co-immunoprecipitation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HAW8&geneProductId=UniProtKB:Q9HAW8

determination method

determination method

1 reference

27 March 2018

Alternatively spliced products of the UGT1A gene interact with the enzymatically active proteins to inhibit glucuronosyltransferase activity in vitro

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HAW8&geneProductId=UniProtKB:Q9HAW8

determination method

protein kinase C binding

determination method

1 reference

8 April 2019

The major chemical-detoxifying system of UDP-glucuronosyltransferases requires regulated phosphorylation supported by protein kinase C

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAW8

determination method

glucuronosyltransferase activity

determination method

6 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HAW8&geneProductId=UniProtKB:Q9HAW8

determination method

27 March 2018

Alternatively spliced products of the UGT1A gene interact with the enzymatically active proteins to inhibit glucuronosyltransferase activity in vitro

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HAW8&geneProductId=UniProtKB:Q9HAW8

determination method

27 March 2018

Alternatively spliced products of the UGT1A gene interact with the enzymatically active proteins to inhibit glucuronosyltransferase activity in vitro

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HAW8&geneProductId=UniProtKB:Q9HAW8

determination method

27 March 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HAW8&geneProductId=UniProtKB:Q9HAW8

determination method

27 March 2018

Disposition of flavonoids via enteric recycling: enzyme stability affects characterization of prunetin glucuronidation across species, organs, and UGT isoforms

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HAW8&geneProductId=UniProtKB:Q9HAW8

determination method

27 March 2018

Phase II metabolism of hesperetin by individual UDP-glucuronosyltransferases and sulfotransferases and rat and human tissue samples

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HAW8&geneProductId=UniProtKB:Q9HAW8

determination method

UDP-glycosyltransferase activity

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAW8

determination method

glucuronosyltransferase activity

determination method

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAW8

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAW8

determination method

8 April 2019

Phase II metabolism of hesperetin by individual UDP-glucuronosyltransferases and sulfotransferases and rat and human tissue samples

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAW8

determination method

8 April 2019

Disposition of flavonoids via enteric recycling: enzyme stability affects characterization of prunetin glucuronidation across species, organs, and UGT isoforms

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAW8

determination method

protein heterodimerization activity

determination method

1 reference

8 April 2019

Oligomerization of the UDP-glucuronosyltransferase 1A proteins: homo- and heterodimerization analysis by fluorescence resonance energy transfer and co-immunoprecipitation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAW8

determination method

integral component of membrane

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAW8

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAW8

determination method

intracellular membrane-bounded organelle

determination method

1 reference

27 March 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HAW8&geneProductId=UniProtKB:Q9HAW8

determination method

endoplasmic reticulum

determination method

4 references

27 March 2018

Alternatively spliced products of the UGT1A gene interact with the enzymatically active proteins to inhibit glucuronosyltransferase activity in vitro

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HAW8&geneProductId=UniProtKB:Q9HAW8

determination method

27 March 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HAW8&geneProductId=UniProtKB:Q9HAW8

determination method

27 March 2018

Oligomerization of the UDP-glucuronosyltransferase 1A proteins: homo- and heterodimerization analysis by fluorescence resonance energy transfer and co-immunoprecipitation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HAW8&geneProductId=UniProtKB:Q9HAW8

determination method

27 March 2018

The major chemical-detoxifying system of UDP-glucuronosyltransferases requires regulated phosphorylation supported by protein kinase C

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HAW8&geneProductId=UniProtKB:Q9HAW8

determination method

endoplasmic reticulum membrane

determination method

4 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HAW8&geneProductId=UniProtKB:Q9HAW8

determination method

27 March 2018

Alternatively spliced products of the UGT1A gene interact with the enzymatically active proteins to inhibit glucuronosyltransferase activity in vitro

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HAW8&geneProductId=UniProtKB:Q9HAW8

determination method

27 March 2018

Alternatively spliced products of the UGT1A gene interact with the enzymatically active proteins to inhibit glucuronosyltransferase activity in vitro

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HAW8&geneProductId=UniProtKB:Q9HAW8

determination method

27 March 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HAW8&geneProductId=UniProtKB:Q9HAW8

determination method

endoplasmic reticulum

determination method

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAW8

determination method

8 April 2019

Oligomerization of the UDP-glucuronosyltransferase 1A proteins: homo- and heterodimerization analysis by fluorescence resonance energy transfer and co-immunoprecipitation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAW8

determination method

8 April 2019

The major chemical-detoxifying system of UDP-glucuronosyltransferases requires regulated phosphorylation supported by protein kinase C

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAW8

determination method

biological process

negative regulation of cellular glucuronidation

determination method

1 reference

27 March 2018

Alternatively spliced products of the UGT1A gene interact with the enzymatically active proteins to inhibit glucuronosyltransferase activity in vitro

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HAW8&geneProductId=UniProtKB:Q9HAW8

determination method

xenobiotic glucuronidation

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAW8

determination method

flavone metabolic process

determination method

1 reference

8 April 2019

Disposition of flavonoids via enteric recycling: enzyme stability affects characterization of prunetin glucuronidation across species, organs, and UGT isoforms

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAW8

determination method

determination method

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HAW8&geneProductId=UniProtKB:Q9HAW8

determination method

negative regulation of glucuronosyltransferase activity

determination method

1 reference

27 March 2018

Alternatively spliced products of the UGT1A gene interact with the enzymatically active proteins to inhibit glucuronosyltransferase activity in vitro

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HAW8&geneProductId=UniProtKB:Q9HAW8

determination method

negative regulation of fatty acid metabolic process

determination method

1 reference

27 March 2018

Alternatively spliced products of the UGT1A gene interact with the enzymatically active proteins to inhibit glucuronosyltransferase activity in vitro

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HAW8&geneProductId=UniProtKB:Q9HAW8

determination method

cellular glucuronidation

determination method

3 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HAW8&geneProductId=UniProtKB:Q9HAW8

determination method

27 March 2018

Alternatively spliced products of the UGT1A gene interact with the enzymatically active proteins to inhibit glucuronosyltransferase activity in vitro

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HAW8&geneProductId=UniProtKB:Q9HAW8

determination method

27 March 2018

Phase II metabolism of hesperetin by individual UDP-glucuronosyltransferases and sulfotransferases and rat and human tissue samples

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HAW8&geneProductId=UniProtKB:Q9HAW8

determination method

flavonoid glucuronidation

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAW8

determination method

UDP-glycosyltransferase family, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9HAW8

Identifiers

RefSeq protein ID

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000343838

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000343838

ENSP00000362544

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000362544

Sitelinks

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Multilingual sites(0 entries)

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