Serpin family B member 3 (Q21123884)

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mammalian protein found in Homo sapiens

serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3
protein T4-A
serpin peptidase inhibitor, clade B (ovalbumin), member 3
squamous cell carcinoma antigen 1
serpin B3
SCCA-1
SERPINB3

Language	Label	Description	Also known as
English	Serpin family B member 3	mammalian protein found in Homo sapiens	serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3 protein T4-A serpin peptidase inhibitor, clade B (ovalbumin), member 3 squamous cell carcinoma antigen 1 serpin B3 SCCA-1 SERPINB3

Statements

1 reference

13 November 2019

UniProt protein ID

Serpin superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P29508

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P29508

Serpin, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Serpin domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

virus receptor activity

determination method

1 reference

8 April 2019

Squamous cell carcinoma antigen 1-mediated binding of hepatitis B virus to hepatocytes does not involve the hepatic serpin clearance system

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29508

determination method

protease binding

determination method

1 reference

8 April 2019

Increased antiprotease activity of the SERPINB3 polymorphic variant SCCA-PD

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29508

determination method

cysteine-type endopeptidase inhibitor activity

determination method

1 reference

8 April 2019

Increased antiprotease activity of the SERPINB3 polymorphic variant SCCA-PD

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29508

determination method

peptidase inhibitor activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29508

determination method

serine-type endopeptidase inhibitor activity

determination method

3 references

8 April 2019

A serine proteinase inhibitor locus at 18q21.3 contains a tandem duplication of the human squamous cell carcinoma antigen gene

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29508

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29508

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29508

determination method

determination method

3 references

26 September 2017

SERPINB3 induces epithelial-mesenchymal transition

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29508&geneProductId=UniProtKB:P29508

determination method

26 September 2017

Increased antiprotease activity of the SERPINB3 polymorphic variant SCCA-PD

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29508&geneProductId=UniProtKB:P29508

determination method

26 September 2017

Proteomic characterization of the human sperm nucleus

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29508&geneProductId=UniProtKB:P29508

determination method

determination method

1 reference

26 September 2017

Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29508&geneProductId=UniProtKB:P29508

determination method

cytoplasmic vesicle

determination method

1 reference

8 April 2019

Increased antiprotease activity of the SERPINB3 polymorphic variant SCCA-PD

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29508

determination method

extracellular exosome

determination method

3 references

26 September 2017

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29508&geneProductId=UniProtKB:P29508

determination method

26 September 2017

Large-scale proteomics and phosphoproteomics of urinary exosomes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29508&geneProductId=UniProtKB:P29508

determination method

26 September 2017

Proteomic identification of exosomal LRG1: a potential urinary biomarker for detecting NSCLC

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29508&geneProductId=UniProtKB:P29508

determination method

extracellular region

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29508

determination method

azurophil granule lumen

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29508

determination method

determination method

3 references

8 April 2019

SERPINB3 induces epithelial-mesenchymal transition

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29508

determination method

8 April 2019

Increased antiprotease activity of the SERPINB3 polymorphic variant SCCA-PD

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29508

determination method

8 April 2019

Proteomic characterization of the human sperm nucleus

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29508

determination method

determination method

1 reference

8 April 2019

Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29508

determination method

extracellular exosome

determination method

1 reference

8 April 2019

Large-scale proteomics and phosphoproteomics of urinary exosomes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29508

determination method

biological process

paracrine signaling

determination method

1 reference

8 April 2019

SERPINB3 induces epithelial-mesenchymal transition

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29508

determination method

positive regulation of cell population proliferation

determination method

1 reference

8 April 2019

SERPINB3 induces epithelial-mesenchymal transition

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29508

determination method

autocrine signaling

determination method

1 reference

8 April 2019

SERPINB3 induces epithelial-mesenchymal transition

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29508

determination method

negative regulation of catalytic activity

determination method

1 reference

8 April 2019

Circulating serpin tumor markers SCCA1 and SCCA2 are not actively secreted but reside in the cytosol of squamous carcinoma cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29508

determination method

negative regulation of JUN kinase activity

determination method

1 reference

8 April 2019

Increased antiprotease activity of the SERPINB3 polymorphic variant SCCA-PD

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29508

determination method

positive regulation of endopeptidase activity

determination method

1 reference

8 April 2019

SERPINB3 induces epithelial-mesenchymal transition

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29508

determination method

positive regulation of epithelial to mesenchymal transition

determination method

1 reference

8 April 2019

SERPINB3 induces epithelial-mesenchymal transition

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29508

determination method

negative regulation of proteolysis

determination method

1 reference

8 April 2019

Squamous cell carcinoma antigen 1-mediated binding of hepatitis B virus to hepatocytes does not involve the hepatic serpin clearance system

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29508

determination method

negative regulation of endopeptidase activity

determination method

1 reference

26 September 2017

Increased antiprotease activity of the SERPINB3 polymorphic variant SCCA-PD

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29508&geneProductId=UniProtKB:P29508

determination method

positive regulation of cell migration

determination method

1 reference

8 April 2019

SERPINB3 induces epithelial-mesenchymal transition

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29508

determination method

viral entry into host cell

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29508

determination method

neutrophil degranulation

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29508

determination method

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P29508

Serpin, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P29508

Identifiers

RefSeq protein ID

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000283752

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000283752

ENSP00000329498

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000329498

PDB structure ID

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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