TIAM Rac1 associated GEF 1 (Q21123942)

T-lymphoma invasion and metastasis-inducing protein 1

1 reference

PDZ superfamily

1 reference

PH-like domain superfamily

1 reference

pleckstrin homology domain, protein family

1 reference

PDZ domain, protein family

1 reference

Raf-like Ras-binding domain, protein family

1 reference

Dbl homology (DH) domain, protein family

1 reference

Guanine-nucleotide dissociation stimulator, CDC24, conserved site, protein family

1 reference

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

1 reference

8 April 2019

Tiam1 regulates the Wnt/Dvl/Rac1 signaling pathway and the differentiation of midbrain dopaminergic neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

3 references

8 April 2019

Tiam1 regulates the Wnt/Dvl/Rac1 signaling pathway and the differentiation of midbrain dopaminergic neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

8 April 2019

The Structure of the Tiam1 PDZ Domain/ Phospho-Syndecan1 Complex Reveals a Ligand Conformation that Modulates Protein Dynamics

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

8 April 2019

The Rac1 guanine nucleotide exchange factor Tiam1 mediates EphB receptor-dependent dendritic spine development

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

guanyl-nucleotide exchange factor activity

4 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13009&geneProductId=UniProtKB:Q13009

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13009&geneProductId=UniProtKB:Q13009

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13009&geneProductId=UniProtKB:Q13009

16 July 2018

The Rac1-GEF Tiam1 couples the NMDA receptor to the activity-dependent development of dendritic arbors and spines

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13009&geneProductId=UniProtKB:Q13009

receptor tyrosine kinase binding

EXP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

guanyl-nucleotide exchange factor activity

3 references

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

8 April 2019

Tiam1 regulates the Wnt/Dvl/Rac1 signaling pathway and the differentiation of midbrain dopaminergic neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

1 reference

8 April 2019

CCM1 regulates vascular-lumen organization by inducing endothelial polarity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

The Tiam1 PDZ domain couples to Syndecan1 and promotes cell-matrix adhesion

cell-cell contact zone

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

extrinsic component of cytoplasmic side of plasma membrane

1 reference

8 April 2019

The Tiam1 PDZ domain couples to Syndecan1 and promotes cell-matrix adhesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

somatodendritic compartment

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

glutamatergic synapse

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

extrinsic component of postsynaptic density membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

protein localization to membrane

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

regulation of insulin secretion involved in cellular response to glucose stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

intracellular signal transduction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

activation of GTPase activity

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

8 April 2019

Tiam1 regulates the Wnt/Dvl/Rac1 signaling pathway and the differentiation of midbrain dopaminergic neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

positive regulation of JUN kinase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

ephrin receptor signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

cardiac muscle hypertrophy

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

regulation of non-canonical Wnt signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

positive regulation of axonogenesis

ISS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

neuron projection extension

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

Wnt signaling pathway, planar cell polarity pathway

1 reference

8 April 2019

Wnt signaling in midbrain dopaminergic neuron development and regenerative medicine for Parkinson's disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

regulation of dopaminergic neuron differentiation

NAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

regulation of ERK1 and ERK2 cascade

ISS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

positive regulation of neuron projection development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

positive regulation of apoptotic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

positive regulation of Schwann cell chemotaxis

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

positive regulation of protein binding

1 reference

8 April 2019

Tiam1 regulates the Wnt/Dvl/Rac1 signaling pathway and the differentiation of midbrain dopaminergic neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

1 reference

8 April 2019

The Tiam1 PDZ domain couples to Syndecan1 and promotes cell-matrix adhesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

Rac protein signal transduction

IMP

1 reference

8 April 2019

The Tiam1 PDZ domain couples to Syndecan1 and promotes cell-matrix adhesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

regulation of Rho protein signal transduction

IMP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

regulation of small GTPase mediated signal transduction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

1 reference

8 April 2019

The Tiam1 PDZ domain couples to Syndecan1 and promotes cell-matrix adhesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

positive regulation of dendritic spine morphogenesis

IMP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

positive regulation of cell population proliferation

1 reference

8 April 2019

miR-29b suppresses tumor growth and metastasis in colorectal cancer via downregulating Tiam1 expression and inhibiting epithelial-mesenchymal transition

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

NMDA selective glutamate receptor signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

regulation of modification of postsynaptic actin cytoskeleton

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

regulation of epithelial to mesenchymal transition

1 reference

8 April 2019

miR-21 and miR-31 converge on TIAM1 to regulate migration and invasion of colon carcinoma cells

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

positive regulation of epithelial to mesenchymal transition

1 reference

8 April 2019

Tiam1 regulates cell adhesion, migration and apoptosis in colon tumor cells

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

G protein-coupled receptor signaling pathway

NAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009

1 reference

Raf-like Ras-binding

1 reference

Dbl homology (DH) domain

1 reference

pleckstrin homology domain

1 reference

Guanine-nucleotide dissociation stimulator, CDC24, conserved site

1 reference

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016