Histidine rich calcium binding protein (Q21125125)

http://www.ebi.ac.uk/interpro/protein/P23327

Histidine-rich calcium-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

Histidine-rich Ca-binding protein interacts with sarcoplasmic reticulum Ca-ATPase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23327

transmembrane transporter binding

IPI

1 reference

8 April 2019

Histidine-rich Ca-binding protein interacts with sarcoplasmic reticulum Ca-ATPase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23327

3 references

8 April 2019

The arrhythmogenic human HRC point mutation S96A leads to spontaneous Ca(2+) release due to an impaired ability to buffer store Ca(2+)

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23327

8 April 2019

Abnormal calcium cycling and cardiac arrhythmias associated with the human Ser96Ala genetic variant of histidine-rich calcium-binding protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23327

8 April 2019

Histidine-rich Ca-binding protein interacts with sarcoplasmic reticulum Ca-ATPase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23327

3 references

8 April 2019

cDNA and genomic cloning of HRC, a human sarcoplasmic reticulum protein, and localization of the gene to human chromosome 19 and mouse chromosome 7

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23327

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23327

8 April 2019

Abnormal calcium cycling and cardiac arrhythmias associated with the human Ser96Ala genetic variant of histidine-rich calcium-binding protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23327

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23327

IDA

cell component

sarcoplasmic reticulum

1 reference

8 April 2019

1 reference

8 April 2019

Abnormal calcium cycling and cardiac arrhythmias associated with the human Ser96Ala genetic variant of histidine-rich calcium-binding protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23327

sarcoplasmic reticulum membrane

IDA

1 reference

16 July 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23327&geneProductId=UniProtKB:P23327

endoplasmic reticulum lumen

IEA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23327

1 reference

8 April 2019

cDNA and genomic cloning of HRC, a human sarcoplasmic reticulum protein, and localization of the gene to human chromosome 19 and mouse chromosome 7

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23327

regulation of ryanodine-sensitive calcium-release channel activity

TAS

1 reference

8 April 2019

Abnormal calcium cycling and cardiac arrhythmias associated with the human Ser96Ala genetic variant of histidine-rich calcium-binding protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23327

regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum

1 reference

8 April 2019

Abnormal calcium cycling and cardiac arrhythmias associated with the human Ser96Ala genetic variant of histidine-rich calcium-binding protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23327

positive regulation of relaxation of cardiac muscle

1 reference

8 April 2019

Abnormal calcium cycling and cardiac arrhythmias associated with the human Ser96Ala genetic variant of histidine-rich calcium-binding protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23327

The Ser96Ala variant in histidine-rich calcium-binding protein is associated with life-threatening ventricular arrhythmias in idiopathic dilated cardiomyopathy

regulation of heart rate

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23327

regulation of calcium ion transmembrane transport

IMP

1 reference

8 April 2019

Abnormal calcium cycling and cardiac arrhythmias associated with the human Ser96Ala genetic variant of histidine-rich calcium-binding protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23327

positive regulation of heart rate

1 reference

8 April 2019

Abnormal calcium cycling and cardiac arrhythmias associated with the human Ser96Ala genetic variant of histidine-rich calcium-binding protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23327

Ensembl genome database project

calcium ion homeostasis

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23327&geneProductId=UniProtKB:P23327

regulation of peptidyl-serine phosphorylation

IEA

1 reference

8 April 2019

Abnormal calcium cycling and cardiac arrhythmias associated with the human Ser96Ala genetic variant of histidine-rich calcium-binding protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23327

regulation of heart contraction

1 reference

16 July 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23327&geneProductId=UniProtKB:P23327

regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion

IEA

1 reference

8 April 2019

Histidine-rich Ca-binding protein interacts with sarcoplasmic reticulum Ca-ATPase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23327

regulation of cytosolic calcium ion concentration

TAS

1 reference

8 April 2019

Abnormal calcium cycling and cardiac arrhythmias associated with the human Ser96Ala genetic variant of histidine-rich calcium-binding protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23327

positive regulation of heart contraction

1 reference

8 April 2019

Abnormal calcium cycling and cardiac arrhythmias associated with the human Ser96Ala genetic variant of histidine-rich calcium-binding protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23327

regulation of cell communication by electrical coupling involved in cardiac conduction

1 reference

8 April 2019

Abnormal calcium cycling and cardiac arrhythmias associated with the human Ser96Ala genetic variant of histidine-rich calcium-binding protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23327

post-translational protein modification

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23327

negative regulation of cytosolic calcium ion concentration

TAS

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23327&geneProductId=UniProtKB:P23327

Histidine-rich calcium-binding

IBA

has part(s)

1 reference

stated in

InterPro Release 71.0