Interferon induced protein with tetratricopeptide repeats 5 (Q21131535)

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mammalian protein found in Homo sapiens

IFIT-5
IFIT5
retinoic acid- and interferon-inducible 58 kDa protein
interferon-induced 58 kDa protein
interferon-induced protein with tetratricopeptide repeats 5
P58
retinoic acid- and interferon-inducible protein (58kD)

Language	Label	Description	Also known as
English	Interferon induced protein with tetratricopeptide repeats 5	mammalian protein found in Homo sapiens	IFIT-5 IFIT5 retinoic acid- and interferon-inducible 58 kDa protein interferon-induced 58 kDa protein interferon-induced protein with tetratricopeptide repeats 5 P58 retinoic acid- and interferon-inducible protein (58kD)

Statements

1 reference

13 November 2019

UniProt protein ID

Tetratricopeptide-like helical domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q13325

Interferon-induced protein with tetratricopeptide repeat 5

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q13325

Tetratricopeptide repeat-containing domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Tetratricopeptide repeat family

1 reference

based on heuristic

inferred from protein domain or family

Tetratricopeptide repeat 2 family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

single-stranded RNA binding

determination method

3 references

8 April 2019

Crystal structure and nucleotide selectivity of human IFIT5/ISG58

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13325

determination method

8 April 2019

Broad and adaptable RNA structure recognition by the human interferon-induced tetratricopeptide repeat protein IFIT5

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13325

determination method

8 April 2019

Structural basis for viral 5'-PPP-RNA recognition by human IFIT proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13325

determination method

determination method

3 references

31 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13325&geneProductId=UniProtKB:Q13325

determination method

31 October 2017

IFIT1 is an antiviral protein that recognizes 5'-triphosphate RNA

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13325&geneProductId=UniProtKB:Q13325

determination method

31 October 2017

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13325&geneProductId=UniProtKB:Q13325

determination method

RNA cap binding

determination method

1 reference

8 April 2019

Broad and adaptable RNA structure recognition by the human interferon-induced tetratricopeptide repeat protein IFIT5

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13325

determination method

double-stranded DNA binding

determination method

1 reference

8 April 2019

Crystal structure and nucleotide selectivity of human IFIT5/ISG58

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13325

determination method

protein binding

determination method

1 reference

8 April 2019

IFIT5 positively regulates NF-κB signaling through synergizing the recruitment of IκB kinase (IKK) to TGF-β-activated kinase 1 (TAK1)

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13325

determination method

poly(U) RNA binding

determination method

1 reference

8 April 2019

Broad and adaptable RNA structure recognition by the human interferon-induced tetratricopeptide repeat protein IFIT5

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13325

determination method

determination method

4 references

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13325&geneProductId=UniProtKB:Q13325

determination method

1 January 2018

IFIT1 is an antiviral protein that recognizes 5'-triphosphate RNA

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13325&geneProductId=UniProtKB:Q13325

determination method

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13325&geneProductId=UniProtKB:Q13325

determination method

1 January 2018

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13325&geneProductId=UniProtKB:Q13325

determination method

protein binding

determination method

determination method

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13325

determination method

8 April 2019

IFIT1 is an antiviral protein that recognizes 5'-triphosphate RNA

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13325

determination method

8 April 2019

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13325

determination method

cell projection

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13325

determination method

apical part of cell

determination method

1 reference

8 April 2019

tRNA binding, structure, and localization of the human interferon-induced protein IFIT5

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13325

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13325

determination method

intracellular membrane-bounded organelle

determination method

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13325

determination method

actin cytoskeleton

determination method

1 reference

8 April 2019

tRNA binding, structure, and localization of the human interferon-induced protein IFIT5

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13325

determination method

IkappaB kinase complex

determination method

1 reference

8 April 2019

IFIT5 positively regulates NF-κB signaling through synergizing the recruitment of IκB kinase (IKK) to TGF-β-activated kinase 1 (TAK1)

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13325

determination method

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13325

determination method

biological process

innate immune response

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13325

determination method

immune system process

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13325

determination method

positive regulation of I-kappaB kinase/NF-kappaB signaling

determination method

1 reference

8 April 2019

IFIT5 positively regulates NF-κB signaling through synergizing the recruitment of IκB kinase (IKK) to TGF-β-activated kinase 1 (TAK1)

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13325

determination method

negative regulation of viral genome replication

determination method

1 reference

8 April 2019

Crystal structure and nucleotide selectivity of human IFIT5/ISG58

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13325

determination method

defense response to virus

determination method

3 references

8 April 2019

Structural basis for viral 5'-PPP-RNA recognition by human IFIT proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13325

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13325

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13325

determination method

Tetratricopeptide repeat-containing domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q13325

Tetratricopeptide repeat 2

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q13325

tetratricopeptide repeat

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q13325

Identifiers

RefSeq protein ID

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000360860

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000360860

PDB structure ID

1 reference

UniProt protein ID

20 March 2016

language of work or name

1 reference

UniProt protein ID

20 March 2016

language of work or name

1 reference

UniProt protein ID

20 March 2016

language of work or name

1 reference

UniProt protein ID

20 March 2016

language of work or name

1 reference

UniProt protein ID

20 March 2016

language of work or name

1 reference

UniProt protein ID

20 March 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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